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siomycin A

Product Name
siomycin A
CAS No.
12656-09-6
Chemical Name
siomycin A
Synonyms
siomycin A;Salomycin A;Mutabilycin;Mutabillicin;Antibiotic 6741-21;AKFVOKPQHFBYCA-OFENGFFDSA-N;Mutabilycin, SporangioMycin, 6741-21, Mutabillicin;Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...
CBNumber
CB91371285
Molecular Formula
C71H81N19O18S5
Formula Weight
1648.84
MOL File
12656-09-6.mol
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siomycin A Property

Density 
1.65±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: complete10 mg/ml, clear, colorless to faintly yellow
form 
White solid.
pka
10.43±0.46(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15378
Product name
Siomycin A
Purity
≥95%
Packaging
500μg
Price
$396
Updated
2024/03/01
TRC
Product number
S497053
Product name
Siomycin A
Packaging
1000μg
Price
$545
Updated
2021/12/16
Usbiological
Product number
S1013-86W
Product name
Siomycin A
Packaging
500ug
Price
$582
Updated
2021/12/16
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siomycin A Chemical Properties,Usage,Production

Uses

Siomycin A is an antibiotic that inhibits FoxM1.

Uses

Siomycin is a macrocyclic antibiotic with potent and selective antibacterial activity discovered in 1969. Siomycin is a potent inhibitor of the oncogenic transcription factor, FoxM1. The reduced transcription activity is reflected in the down regulation of protein and mRNA levels of FoxM1 and effects on down stream genes, Cdc25B, survivin and CENPB. In vitro, siomycin inhibits FoxM1-induced cell growth on soft agar and selectively kill transformed but not normal cells.

siomycin A Preparation Products And Raw materials

Raw materials

Preparation Products

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siomycin A Suppliers

BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

12656-09-6, siomycin ARelated Search:


  • Antibiotic 6741-21
  • Mutabillicin
  • Mutabilycin
  • AKFVOKPQHFBYCA-OFENGFFDSA-N
  • siomycin A
  • Mutabilycin, SporangioMycin, 6741-21, Mutabillicin
  • Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...
  • Salomycin A
  • 12656-09-6
  • C71H81N19O18S5