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glycyl-glycyl-cysteine

Product Name
glycyl-glycyl-cysteine
CAS No.
95416-30-1
Chemical Name
glycyl-glycyl-cysteine
Synonyms
Gly-Gly-Cys;Gly-Gly-L-Cys;glycyl-glycyl-cysteine;L-Cysteine, glycylglycyl-;(2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid
CBNumber
CB91378284
Molecular Formula
C7H13N3O4S
Formula Weight
235.26
MOL File
95416-30-1.mol
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glycyl-glycyl-cysteine Property

pka
pK1:2.71;pK2:2.71;pK3:7.94;pK4:7.94 (35°C)
Sequence
H-Gly-Gly-Cys-OH
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Hazard and Precautionary Statements (GHS)

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glycyl-glycyl-cysteine Chemical Properties,Usage,Production

Uses

Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin[1].

Definition

ChEBI: Gly-Gly-Cys is an oligopeptide.

References

[1] Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71. DOI:10.1016/j.thromres.2004.12.023

glycyl-glycyl-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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glycyl-glycyl-cysteine Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
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12952
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95416-30-1, glycyl-glycyl-cysteineRelated Search:


  • glycyl-glycyl-cysteine
  • Gly-Gly-L-Cys
  • L-Cysteine, glycylglycyl-
  • (2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid
  • Gly-Gly-Cys
  • 95416-30-1