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6 beta-hydroxycortisol

Product Name
6 beta-hydroxycortisol
CAS No.
53-35-0
Chemical Name
6 beta-hydroxycortisol
Synonyms
NSC 76163;(6β,11β)-;Hydrocortisone IMpurity D;6-β-Hydroxy Hydrocortisone;Hydrocortisone EP Impurity D;6,17-Dihydroxycorticosterone;Hydrocortisone impurity D (EP);6beta,11beta,17,21-Tetrahydroxypreg;6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione;(6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
CBNumber
CB91379726
Molecular Formula
C21H30O6
Formula Weight
378.46
MOL File
53-35-0.mol
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6 beta-hydroxycortisol Property

Melting point:
182-190?C
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
H922300
Product name
6β-HydroxyCortisol
Packaging
25mg
Price
$1295
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0000599
Product name
6-BETA-HYDROXYCORTISOL
Purity
95.00%
Packaging
5MG
Price
$501.02
Updated
2021/12/16
Labseeker
Product number
SC-65652
Product name
6beta,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione(6beta-Hydroxyhydrocortisone)
Purity
95
Packaging
10g
Price
$1666
Updated
2021/12/16
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6 beta-hydroxycortisol Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A metabolite of Cortisol

Definition

ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol.

6 beta-hydroxycortisol Preparation Products And Raw materials

Raw materials

Preparation Products

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6 beta-hydroxycortisol Suppliers

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53-35-0, 6 beta-hydroxycortisolRelated Search:


  • (6β,11β)-
  • Hydrocortisone IMpurity D
  • (6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-diMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • Hydrocortisone impurity D (EP)
  • (6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
  • 6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione
  • 6,17-Dihydroxycorticosterone
  • NSC 76163
  • Hydrocortisone EP Impurity D
  • Hydrocortisone Impurity 4(Hydrocortisone EP Impurity D)
  • 6beta,11beta,17,21-Tetrahydroxypreg
  • Pregn-4-ene-3,20-dione, 6,11,17,21-tetrahydroxy-, (6β,11β)-
  • Hydrocortisone EP Impurity D (6β-Hydroxycortisol/ 6β-Hydroxyhydrocortisone)
  • 6-β-Hydroxy Hydrocortisone
  • (6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity)
  • 53-35-0
  • Metabolites & Impurities
  • Steroids
  • Intermediates & Fine Chemicals
  • Pharmaceuticals