ChemicalBook > CAS DataBase List > viridicatumtoxin

viridicatumtoxin

Product Name
viridicatumtoxin
CAS No.
39277-41-3
Chemical Name
viridicatumtoxin
Synonyms
NSC 159628;viridicatumtoxin;Spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide, 7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-, (1R,7'aR,11'aR,12'R)-rel-(-)-
CBNumber
CB91382922
Molecular Formula
C30H31NO10
Formula Weight
565.57
MOL File
39277-41-3.mol
More
Less

viridicatumtoxin Property

Melting point:
235°C (rough estimate)
Boiling point:
630.75°C (rough estimate)
Density 
1.3203 (rough estimate)
refractive index 
1.6310 (estimate)
storage temp. 
Store at -20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
25480
Product name
Viridicatumtoxin
Purity
≥98%
Packaging
1mg
Price
$227
Updated
2024/03/01
Cayman Chemical
Product number
25480
Product name
Viridicatumtoxin
Purity
≥98%
Packaging
5mg
Price
$954
Updated
2024/03/01
TRC
Product number
V673905
Product name
Viridicatumtoxin
Packaging
1mg
Price
$230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BIO0000728
Product name
VIRIDICATUMTOXIN
Purity
95.00%
Packaging
5MG
Price
$504.9
Updated
2021/12/16
AK Scientific
Product number
2060DM
Product name
Viridicatumtoxin
Packaging
5mg
Price
$1161
Updated
2021/12/16
More
Less

viridicatumtoxin Chemical Properties,Usage,Production

Description

Viridicatumtoxin in a mycotoxin originally isolated from Penicillium that has diverse biological activities, including antimicrobial, cytotoxic, and toxic properties. It inhibits the growth of B. subtilis, M. luteus, C. perfringens, B. fragilis, and methicillin-resistant S. aureus (MRSA; MICs = 0.39-1.56 μg/ml), as well as C. albicans, S. cerevisiae, M. racemosus, A. niger, and P. chrysogenum (MICs = 6.2-25 μg/ml), but has no activity against M. smegmatis, E. coli, K. pneumoniae, P. aeruginosa, or S. marcescens (MICs = >100 μg/ml). Viridicatumtoxin inhibits the production of polyprenyl alcohols by S. aureus undecaprenyl pyrophosphate (UPP) synthase, E. coli octaprenyl pyrophosphate synthase (OPS), and S. cerevisiae dehydrodolichyl pyrophosphate (DedoIPP) synthase in vitro (IC50s = 3.1, 21, and 71 μM, respectively). It has cytotoxic effects against human Jurkat T (IC50 = 4.92 μM), chronic lymphocytic leukemia (CLL; LC50 = 0.7-3.5 nM), and bone marrow-derived HS-5 stromal cells. Viridicatumtoxin is toxic to rats and mice when administered intraperitoneally (LD50s = 80 and 90 mg/kg, respectively) and to rats when administered via gastric intubation (LD50 = 122.4 mg/kg), but not to rats or mice when administered orally or through subcutaneous injection.

Uses

Viridicatumtoxin is a tetracycline-like metabolite produced by several species of Penicillium, first isolated in 1976 as a mycotoxin. Initial testing revealed that viridicatumtoxin caused myocardial deterioration, renal tubule necrosis and spleen atrophy. Analogous to the related tetracyclines, viridicatumtoxin was found to be a potent antibacterial, with activity against S. aureus including MRSA and QRSA strains. Little has been published on the mode of action of viridicatumtoxin.

Uses

Viridicatumtoxin is a tetracycline-like metabolite produced by several species of Penicillium.

Definition

ChEBI: A tetracycline-like polyketide antibiotic that is produced by several species of Penicillium and Aspergillus.

viridicatumtoxin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

viridicatumtoxin Suppliers

China 10 India 1 United Kingdom 1 United States 4 Global 16
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
Email
info@scrbio.com
Country
China
ProdList
10329
Advantage
58

39277-41-3, viridicatumtoxinRelated Search:

2-ACETYL-1-TETRALONE 1,6-DIMETHYLNAPHTHALENE 6'-Methoxy-2'-propiononaphthone Nabumetone 1,6-Dihydroxynaphthalene 5-METHOXY-1-TETRALONE 2-Acetyl-6-methoxynaphthalene 2-Methyl-1-tetralone 1,3-DIHYDROXYNAPHTHALENE 2,3,5-TRIMETHYLNAPHTHALENE 1'-HYDROXY-2'-ACETONAPHTHONE 8-METHYL-2-NAPHTHOL viridicatumtoxin cis-5,6,7,8-tetrahydronaphthalene-1,6,7-triol (S)-(-)-ALPHA-METHYL-2-NAPHTHALENEMETHANOL 1,3-Butanedione, 1-(6-methoxy-2-naphthalenyl)- 2-(2,6-DIMETHYLPHENYL)ETHANOL 2,4,5-TRIMETHYLNAPHTHALENE

  • viridicatumtoxin
  • NSC 159628
  • Spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide, 7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-, (1R,7'aR,11'aR,12'R)-rel-(-)-
  • 39277-41-3
  • C30H31NO10