Monomethyl succinate

Product Name: Monomethyl succinate
CAS No.: 77341-67-4
Chemical Name: Monomethyl succinate
Synonyms: Monomethyl succinate;Mononmethyl succinate;MONO-MENTHYLSUCCINATE;(-)-Menthyl Succinate;(-)-MenthylSuccinate>Succinic Acid (-)-Menthyl Ester;Succinic acid menthol monoester;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Succinate;Butanedioic acid mono-(5-methyl-2-isopropyl-cyclohexyl) ester;Succinic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester
CBNumber: CB91424891
Molecular Formula: C14H24O4
Formula Weight: 256.34
MOL File: 77341-67-4.mol

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Monomethyl succinate Property

Melting point:: 62.0 to 66.0 °C
Boiling point:: 374.3±25.0 °C(Predicted)
Density: 1.06±0.1 g/cm3(Predicted)
FEMA: 3810 | MONO-MENTHYL SUCCINATE
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.42±0.17(Predicted)
color: White to Almost white
Odor: at 100.00 %. odorless
Odor Type: odorless
JECFA Number: 447
LogP: 4.35
EPA Substance Registry System: Butanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester (77341-67-4)

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Safety

HS Code: 2917.19.7050

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H318Causes serious eye damage
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2482
Product name: (-)-Menthyl Succinate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $101
Updated: 2025/07/31

Matrix Scientific

Product number: 096892
Product name: 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)-oxy)-4-oxobutanoic acid
Purity: 95+%
Packaging: 1g
Price: $19
Updated: 2021/12/16

AK Scientific

Product number: J56326
Product name: (-)-Menthyl Succinate
Packaging: 5g
Price: $27
Updated: 2021/12/16

Matrix Scientific

Product number: 096892
Product name: 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)-oxy)-4-oxobutanoic acid
Purity: 95+%
Packaging: 5g
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 39229
Product name: (-)-Menthylsuccinate,98%(Assaybytitration,GC)
Purity: 98%(Assaybytitration,GC)
Packaging: 25G
Price: $98.56
Updated: 2021/12/16

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Monomethyl succinate Chemical Properties,Usage,Production

Chemical Properties

mono-Menthyl succinate has a mint, cooling taste.

Uses

Mono-methyl Succinate is one of the substances used in the study of lactobacillus plantarum culture supernatants with potential pro-heating and anti-pathogenic properties in skin chronic wounds

Aroma threshold values

Aroma characteristics at 1.0%: little or no apparent aroma.

Taste threshold values

Threshold in water: 40 ppm. Taste characteristics at 100 ppm: lingering cooling with a slightly oily mouthfeel.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 2039, 1986 DOI: 10.1021/jo00361a019

Synthesis

108-30-5

2216-51-5

77341-67-4

Synthesis Example 1: Synthesis of 1-menthyl-(1-menthoxyethyl) succinate Synthesis of Compound 1: To a 100 mL autoclave, 10.00 g (63.99 mmol) of L-menthol and 6.40 g (63.96 mmol) of succinic anhydride were added, and the air in the autoclave was replaced with nitrogen. Subsequently, the mixture was stirred at 110°C for 8 hours. After completion of the reaction, it was cooled to room temperature and 100 mL of hexane was added to the reaction mixture. The precipitated crystals were filtered and the hexane phase of the filtrate was concentrated to give 16.61 g of 1-menthylsuccinic acid with purity >99.9%.

References

[1] Patent: US2011/81393, 2011, A1. Location in patent: Page/Page column 10
[2] Molecules, 2005, vol. 10, # 1, p. 81 - 97
[3] Molecular Crystals and Liquid Crystals, 2015, vol. 609, # 1, p. 31 - 39
[4] Patent: US2009/28803, 2009, A1

Monomethyl succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Monomethyl succinate Suppliers

Americas 2 China 101 Europe 1 India 3 Japan 1 United States 15 Global 123

Anhui Yunhefei Spice Co., Ltd.

Tel: 15755158983
Email: yunhefei@foxmail.com
Country: China
ProdList: 36
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5001
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View Lastest Price from Monomethyl succinate manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: Monomethyl succinate 77341-67-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.00%
Supply Ability: 20tons
Release date: 2023-09-14

JINING XINHE CHEMICAL CO., LTD

Product: Monomethyl succinate 77341-67-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-07-22

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid 77341-67-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

77341-67-4, Monomethyl succinateRelated Search:

Cyclohexylmethyl bromide Metroprolol succinate (2-Methoxyethyl)benzene Disodium succinate Methyl 2-hydroxyethyl cellulose Methanol Ethylcyclohexane (-)-Menthyl lactate Methylparaben ISOPROPYL LAURATE 6alpha-Methylprednisolone sodium succinate Tribenuron methyl iron succinate Isopropyl alcohol Methylcyclohexane Succinic acid Dioctyl sulfosuccinate sodium salt Methyl salicylate

MONO-MENTHYLSUCCINATE

4-(((1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl)oxy)-4-oxobutanoic acid

Butanedioic acid mono-(5-methyl-2-isopropyl-cyclohexyl) ester

Monomethyl succinate

Mononmethyl succinate

4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid

(-)-MenthylSuccinate&gt

Butanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester

(-)-Menthyl Succinate

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Succinate

Succinic Acid (-)-Menthyl Ester

Succinic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester

Succinic acid menthol monoester

4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoicaci

[1R-(1-α,2β,5α)]-mono[5-methyl-2-(1-methylethyl)cyclohexyl]butanedioate

77341-67-4