Platelet Activating Factor-16
- Product Name
- Platelet Activating Factor-16
- CAS No.
- 74389-68-7
- Chemical Name
- Platelet Activating Factor-16
- Synonyms
- PAF;C16PAF;ACGEPC;PAF (C16);C16-02:0 PC;PAF (C16),99%;C16-PAF-acether;C16 ENANTIOMERIC PAF;Rabbit Anti-PAF antibody;PLATELET ACTIVATING FACTOR
- CBNumber
- CB9143348
- Molecular Formula
- C26H54NO7P
- Formula Weight
- 523.68
- MOL File
- 74389-68-7.mol
Platelet Activating Factor-16 Property
- Melting point:
- 247 °C
- storage temp.
- -20°C
- solubility
- Soluble in H2O or ethanol
- form
- lyophilized powder
- Water Solubility
- Soluble to 100 mM in water
- BRN
- 3574588
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-38-40-48/20/22
- Safety Statements
- 36/37-24/25-22
- RIDADR
- UN 1888 6.1/PG 3
- WGK Germany
- 3
- RTECS
- EC6060000
- F
- 10-21
N-Bromosuccinimide Price
- Product number
- 511075
- Product name
- Platelet Activating Factor-16
- Packaging
- 1mg
- Price
- $54.7
- Updated
- 2024/03/01
- Product number
- 511075
- Product name
- Platelet Activating Factor-16
- Packaging
- 5mg
- Price
- $125
- Updated
- 2024/03/01
- Product number
- 60900
- Product name
- PAF C-16
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 60900
- Product name
- PAF C-16
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- P4904
- Product name
- β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $58.2
- Updated
- 2024/03/01
Platelet Activating Factor-16 Chemical Properties,Usage,Production
Uses
PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line.
Uses
C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.
Definition
ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
General Description
C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.
Biological Activity
Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
Biochem/physiol Actions
Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.
storage
Store at -20°C
Platelet Activating Factor-16 Preparation Products And Raw materials
Raw materials
Preparation Products
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