Platelet Activating Factor-16

Product Name: Platelet Activating Factor-16
CAS No.: 74389-68-7
Chemical Name: Platelet Activating Factor-16
Synonyms: PAF;C16PAF;ACGEPC;PAF (C16);C16-02:0 PC;PAF (C16),99%;C16-PAF-acether;C16-PAF(PAF (C16));C16 ENANTIOMERIC PAF;Rabbit Anti-PAF antibody
CBNumber: CB9143348
Molecular Formula: C26H54NO7P
Formula Weight: 523.68
MOL File: 74389-68-7.mol

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Platelet Activating Factor-16 Property

Melting point:: 247 °C
storage temp.: -20°C
solubility: Soluble in H2O or ethanol
form: lyophilized powder
color: White to off-white
Water Solubility: Soluble to 100 mM in water
BRN: 3574588

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Safety

Hazard Codes: Xn
Risk Statements: 22-38-40-48/20/22
Safety Statements: 36/37-24/25-22
RIDADR: UN 1888 6.1/PG 3
WGK Germany: 3
RTECS: EC6060000
F: 10-21

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 511075
Product name: Platelet Activating Factor-16
Packaging: 1mg
Price: $54.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 511075
Product name: Platelet Activating Factor-16
Packaging: 5mg
Price: $125
Updated: 2024/03/01

Cayman Chemical

Product number: 60900
Product name: PAF C-16
Purity: ≥98%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 60900
Product name: PAF C-16
Purity: ≥98%
Packaging: 10mg
Price: $120
Updated: 2024/03/01

Sigma-Aldrich

Product number: P4904
Product name: β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate
Purity: ≥98%
Packaging: 1mg
Price: $58.2
Updated: 2024/03/01

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Platelet Activating Factor-16 Chemical Properties,Usage,Production

Uses

PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line.

Uses

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.

Definition

ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.

General Description

C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

Biological Activity

Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.

Biochem/physiol Actions

Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.

storage

Store at -20°C

Platelet Activating Factor-16 Preparation Products And Raw materials

Raw materials

Preparation Products

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Platelet Activating Factor-16 Suppliers

Belgium 1 China 51 Germany 2 Switzerland 2 United Kingdom 1 United States 13 Global 70

3B Pharmachem (Wuhan) International Co.,Ltd.

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Sigma-Aldrich

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74389-68-7, Platelet Activating Factor-16Related Search:

N-ACETYLLACTOSAMINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3 phosphorylcholine 3-O-HEXADECYL-2-ACETYL-SN-GLYCERO-1-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-HEXADECYL

L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-ALKYL

C16-02:0 PC

C16PAF

C16 ENANTIOMERIC PAF

1-O-AKYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-PALMITYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE

1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE

1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

ACGEPC

3-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

PLATELET ACTIVATING FACTOR (C16)

PLATELET ACTIVATING FACTOR

PAF

PAF (C16)

1-HEXADECYL-2-ACETYL-SN-GLYCERO-3- &

L-A-PHOSPHATIDYLCHOLINE, B-ACETYL-*GAMMA -O-HEXADECY

PAF[C16] (PLATELET ACTIVATING FACTOR [C1 6])

L-alpha-phosphatidylcholine-beta-acetyl-gamma-o-hexadecylhygroscopic

1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine

β-acetyl-γ-o-hexadecyl-l-α-phosphatidylcholine

1-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

(R)-2-Acetoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

PLATELET ACTIVATING FACTOR-16

1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl, PAF(C16), Platelet activating factor, 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate

Blood platelet-activating factor acether

C16-PAF-acether

PAF (C16),99%

PAF (C16)1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine

(7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide

1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate

2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine

3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl

2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-02:0 PC

β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate

Platelet Activating Factor-16 - CAS 74389-68-7 - Calbiochem

Rabbit Anti-PAF antibody

C16-PAF(PAF (C16))

74389-68-7

Biochemicals and Reagents

BioChemical

Phosphoglycerides

Glycerophosphocholines

Glycerides

Lipids