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Benzene, 1-bromo-4-(1,1-difluoroethyl)-

Product Name
Benzene, 1-bromo-4-(1,1-difluoroethyl)-
CAS No.
1000994-95-5
Chemical Name
Benzene, 1-bromo-4-(1,1-difluoroethyl)-
Synonyms
1-Bromo-4-(1,1-difluoroethyl);4-(1,1-Difluoroethyl)bromobenzene;Bromo-4-(1,1-difluoroethyl)benzene;4-(1,1-Difluoroethyl)phenyl bromide;Benzene, 1-bromo-4-(1,1-difluoroethyl)-;1-Bromo-4-(1,1-difluoroethyl)benzene 95%;4-Bromo-alpha,alpha-difluoroethylbenzene
CBNumber
CB91465658
Molecular Formula
C8H7BrF2
Formula Weight
221.04
MOL File
1000994-95-5.mol
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Benzene, 1-bromo-4-(1,1-difluoroethyl)- Property

Boiling point:
219.0±30.0 °C(Predicted)
Density 
1.495 g/mL at 25 °C
refractive index 
n20/D1.503
Flash point:
82℃
storage temp. 
Sealed in dry,Room Temperature
form 
Powder or Crystalline Powder
color 
Brown
InChI
InChI=1S/C8H7BrF2/c1-8(10,11)6-2-4-7(9)5-3-6/h2-5H,1H3
InChIKey
QXIBKCFAFRHORF-UHFFFAOYSA-N
SMILES
C1(Br)=CC=C(C(F)(F)C)C=C1
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Safety

RIDADR 
UN 2810 6.1 / PGIII
WGK Germany 
3
HazardClass 
6.1
HS Code 
29036990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
729949
Product name
1-Bromo-4-(1,1-difluoroethyl)benzene
Purity
95%
Packaging
1g
Price
$54.46
Updated
2025/07/31
TRC
Product number
B997180
Product name
1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B997180
Product name
1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging
500mg
Price
$155
Updated
2021/12/16
Matrix Scientific
Product number
054391
Product name
1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging
500mg
Price
$47
Updated
2021/12/16
SynQuest Laboratories
Product number
1700-B-21
Product name
1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging
1g
Price
$68
Updated
2021/12/16
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Benzene, 1-bromo-4-(1,1-difluoroethyl)- Chemical Properties,Usage,Production

Synthesis

99-90-1

1000994-95-5

Example 63A Synthesis of 1-bromo-4-(1,1-difluoroethyl)benzene: Under argon protection, 3.0 g (15.07 mmol) of 1-(4-bromophenyl)ethanone was dissolved in 30 mL of dichloromethane, followed by the slow addition of 15.9 mL (120.57 mmol) of [ethyl (trifluoro-lambda4-thioalkyl)amino]ethane (DAST). The reaction mixture was slowly warmed to 50 °C and stirred at this temperature overnight. Upon completion of the reaction, the reaction mixture was slowly poured into ice water. The organic phase was separated and the aqueous phase was extracted three times with dichloromethane. The organic phases were combined and dried with magnesium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/dichloromethane=4:1) to afford 2.56 g (11.58 mmol, 77% yield) of 1-bromo-4-(1,1-difluoroethyl)benzene as a pale yellow liquid. gC-MS (Method 1): rt = 2.84 min; m/z = 220/222 (M)+.

References

[1] Patent: US2012/172448, 2012, A1. Location in patent: Page/Page column 34
[2] Patent: US2010/305111, 2010, A1. Location in patent: Page/Page column 26
[3] Patent: US2011/21489, 2011, A1. Location in patent: Page/Page column 34-35
[4] Patent: EP2921489, 2015, A1. Location in patent: Paragraph 0110; 0111
[5] Patent: WO2015/160665, 2015, A1. Location in patent: Paragraph 00211

Benzene, 1-bromo-4-(1,1-difluoroethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Benzene, 1-bromo-4-(1,1-difluoroethyl)- manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-11
WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-bromo-4-(1,1-difluoroethyl)benzene 1000994-95-5
Price
US $0.00/G
Min. Order
1G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-03
Henan Fengda Chemical Co., Ltd
Product
Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
Price
US $80.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-27

1000994-95-5, Benzene, 1-bromo-4-(1,1-difluoroethyl)-Related Search:

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