Benzene, 1-bromo-4-(1,1-difluoroethyl)-

Product Name: Benzene, 1-bromo-4-(1,1-difluoroethyl)-
CAS No.: 1000994-95-5
Chemical Name: Benzene, 1-bromo-4-(1,1-difluoroethyl)-
Synonyms: 1-Bromo-4-(1,1-difluoroethyl);4-(1,1-Difluoroethyl)bromobenzene;Bromo-4-(1,1-difluoroethyl)benzene;4-(1,1-Difluoroethyl)phenyl bromide;Benzene, 1-bromo-4-(1,1-difluoroethyl)-;1-Bromo-4-(1,1-difluoroethyl)benzene 95%;4-Bromo-alpha,alpha-difluoroethylbenzene
CBNumber: CB91465658
Molecular Formula: C8H7BrF2
Formula Weight: 221.04
MOL File: 1000994-95-5.mol

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Benzene, 1-bromo-4-(1,1-difluoroethyl)- Property

Boiling point:: 219.0±30.0 °C(Predicted)
Density: 1.495 g/mL at 25 °C
refractive index: n20/D1.503
Flash point:: 82℃
storage temp.: Sealed in dry,Room Temperature
form: Powder or Crystalline Powder
color: Brown
InChI: InChI=1S/C8H7BrF2/c1-8(10,11)6-2-4-7(9)5-3-6/h2-5H,1H3
InChIKey: QXIBKCFAFRHORF-UHFFFAOYSA-N
SMILES: C1(Br)=CC=C(C(F)(F)C)C=C1

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Safety

RIDADR: UN 2810 6.1 / PGIII
WGK Germany: 3
HazardClass: 6.1
HS Code: 29036990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 729949
Product name: 1-Bromo-4-(1,1-difluoroethyl)benzene
Purity: 95%
Packaging: 1g
Price: $54.46
Updated: 2025/07/31

TRC

Product number: B997180
Product name: 1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B997180
Product name: 1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 054391
Product name: 1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging: 500mg
Price: $47
Updated: 2021/12/16

SynQuest Laboratories

Product number: 1700-B-21
Product name: 1-Bromo-4-(1,1-difluoroethyl)benzene
Packaging: 1g
Price: $68
Updated: 2021/12/16

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Benzene, 1-bromo-4-(1,1-difluoroethyl)- Chemical Properties,Usage,Production

Synthesis

99-90-1

1000994-95-5

Example 63A Synthesis of 1-bromo-4-(1,1-difluoroethyl)benzene: Under argon protection, 3.0 g (15.07 mmol) of 1-(4-bromophenyl)ethanone was dissolved in 30 mL of dichloromethane, followed by the slow addition of 15.9 mL (120.57 mmol) of [ethyl (trifluoro-lambda4-thioalkyl)amino]ethane (DAST). The reaction mixture was slowly warmed to 50 °C and stirred at this temperature overnight. Upon completion of the reaction, the reaction mixture was slowly poured into ice water. The organic phase was separated and the aqueous phase was extracted three times with dichloromethane. The organic phases were combined and dried with magnesium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/dichloromethane=4:1) to afford 2.56 g (11.58 mmol, 77% yield) of 1-bromo-4-(1,1-difluoroethyl)benzene as a pale yellow liquid. gC-MS (Method 1): rt = 2.84 min; m/z = 220/222 (M)+.

References

[1] Patent: US2012/172448, 2012, A1. Location in patent: Page/Page column 34
[2] Patent: US2010/305111, 2010, A1. Location in patent: Page/Page column 26
[3] Patent: US2011/21489, 2011, A1. Location in patent: Page/Page column 34-35
[4] Patent: EP2921489, 2015, A1. Location in patent: Paragraph 0110; 0111
[5] Patent: WO2015/160665, 2015, A1. Location in patent: Paragraph 00211

Benzene, 1-bromo-4-(1,1-difluoroethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzene, 1-bromo-4-(1,1-difluoroethyl)- Suppliers

China 81 India 3 United Kingdom 3 United States 13 Global 100

Alfa Aesar

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Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

Reax Chemicals

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Country: India
ProdList: 4217
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A.J Chemicals

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Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

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View Lastest Price from Benzene, 1-bromo-4-(1,1-difluoroethyl)- manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-06-11

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1-bromo-4-(1,1-difluoroethyl)benzene 1000994-95-5
Price: US $0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-03

Henan Fengda Chemical Co., Ltd

Product: Benzene, 1-bromo-4-(1,1-difluoroethyl)- 1000994-95-5
Price: US $80.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-27

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1000994-95-5