1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE
- Product Name
- 1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE
- CAS No.
- 4869-46-9
- Chemical Name
- 1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE
- Synonyms
- 1,3-Dimethyl-5-formyluracil;1,3-Dimethyluracil-5-carboxaldehyde;1,3-dimethyl-2,4-dioxopyrimidine-5-carbaldehyde;1,3-dimethyl-2,4-dioxo-pyrimidine-5-carbaldehyde;2,4-diketo-1,3-dimethyl-pyrimidine-5-carbaldehyde;1,2,3,4-tetrahydro-1,3-diMethyl-2,4-dioxopyriMidine-5-carbaldehyde;1,2,3,4-Tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinecarboxaldehyde;5-Pyrimidinecarboxaldehyde, 1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-;1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde(1,?3-?Dimethyluracil-?5-?carboxaldehyde)
- CBNumber
- CB91475565
- Molecular Formula
- C7H8N2O3
- Formula Weight
- 168.15
- MOL File
- 4869-46-9.mol
1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE Property
- Melting point:
- 122-124 °C(Solv: ligroine (8032-32-4))
- Boiling point:
- 274.1±50.0 °C(Predicted)
- Density
- 1.408±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- -3.06±0.40(Predicted)
- Appearance
- Light yellow to brown Solid
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C7H8N2O3/c1-8-3-5(4-10)6(11)9(2)7(8)12/h3-4H,1-2H3
- InChIKey
- KGJFRZOATIXYPW-UHFFFAOYSA-N
- SMILES
- C1(=O)N(C)C=C(C=O)C(=O)N1C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D462058
- Product name
- 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
- Packaging
- 50mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- D462058
- Product name
- 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 6636AB
- Product name
- 1,3-Dimethyluracil-5-carboxaldehyde
- Packaging
- 100mg
- Price
- $96
- Updated
- 2021/12/16
- Product number
- FD147434
- Product name
- 1,3-Dimethyluracil-5-carboxaldehyde
- Packaging
- 100mg
- Price
- $61
- Updated
- 2021/12/16
- Product number
- FD147434
- Product name
- 1,3-Dimethyluracil-5-carboxaldehyde
- Packaging
- 500mg
- Price
- $210
- Updated
- 2021/12/16
1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE Chemical Properties,Usage,Production
Synthesis
1195-08-0
74-88-4
4869-46-9
A slurry was formed by suspending 400 mg of 5-formyluracil (2.8 mM) in 10 mL of DMF at room temperature. Subsequently, 280 mg of sodium hydride (7 mM, 60% oil solution) was added to this slurry. After stirring the reaction mixture for 30 minutes, 1.013 g of iodomethane (7.2 mM) was added. After the reaction mixture was transformed from turbid to a homogeneous yellow solution and complete consumption of 5-formyluracil was confirmed by thin layer chromatography (TLC), the reaction was quenched with methanol and water. The reaction mixture was concentrated on a rotary evaporator and the residue partitioned between methanol and hexane. The methanol phase was concentrated and the residue was again partitioned between chloroform and water. The organic phase was dried over anhydrous magnesium sulfate, filtered and concentrated to give 420 mg (89% yield) of 1,3-dimethyl-5-formyluracil as an off-white waxy solid. The structure of the product was confirmed by 1H-NMR (DMSO-d6, δ= 9.82 (s, 1H), 8.52 (s, 1H), 3.43 (s, 3H), 3.2 (s, 3H) and LC/MS (retention time = 0.34 min, m/z = 169, [M+H]+).
References
[1] Patent: US2006/19965, 2006, A1. Location in patent: Page/Page column 22
[2] European Journal of Organic Chemistry, 2015, vol. 2015, # 30, p. 6624 - 6630
1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-DIMETHYLURACIL-5-CARBOXALDEHYDE manufacturers
- Product
- 1,3-DiMethyluracil-5-carboxaldehyde 4869-46-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-14