5-Chloro-1H-pyrazole-3-carboxylic acid
- Product Name
- 5-Chloro-1H-pyrazole-3-carboxylic acid
- CAS No.
- 881668-70-8
- Chemical Name
- 5-Chloro-1H-pyrazole-3-carboxylic acid
- Synonyms
- 5-Chloropyrazole-3-carboxylic Acid;5-Chloro-1H-pyrazole-3-carboxylic acid;1H-Pyrazole-3-carboxylicacid, 5-chloro-
- CBNumber
- CB91501525
- Molecular Formula
- C4H3ClN2O2
- Formula Weight
- 146.53
- MOL File
- 881668-70-8.mol
5-Chloro-1H-pyrazole-3-carboxylic acid Property
- Boiling point:
- 445.6±25.0 °C(Predicted)
- Density
- 1.714±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.61±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B426005
- Product name
- 5-chloro-1H-pyrazole-3-carboxylicacid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W003620
- Product name
- 5-Chloro-1H-pyrazole-3-carboxylicacid
- Purity
- ≥98.0%
- Packaging
- 250mg
- Price
- $68
- Updated
- 2021/12/16
- Product number
- FC142689
- Product name
- 5-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 50mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FC142689
- Product name
- 5-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 100mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FC142689
- Product name
- 5-Chloro-1H-pyrazole-3-carboxylic acid
- Packaging
- 500mg
- Price
- $325
- Updated
- 2021/12/16
5-Chloro-1H-pyrazole-3-carboxylic acid Chemical Properties,Usage,Production
Synthesis
15953-45-4
881668-70-8
General procedure for the synthesis of 5-chloro-pyrazole-3-carboxylic acid: a solution of potassium permanganate (3.5 g, 22 mmol) in water (120 mL) was added to a solution of 5-chloro-3-methylpyrazole (1.0 g, 8.8 mmol; see Intermediate (III) above) in water (50 mL) and tertiary butyl alcohol (1 mL) in batches over a period of 5 hours at 70 °C. The reaction mixture was stirred at 70 °C overnight and subsequently filtered through diatomaceous earth (Celite). The colorless filtrate was concentrated and acidified with 2 M aqueous hydrochloric acid. After filtration, 5-chloro-pyrazole-3-carboxylic acid was obtained as a white powder, which could be used directly without further purification (yield: 913 mg, 80%).1H-NMR (DMSO-d6) data: δ 6.80 (s, 1H), δ 4.40 (br s, 1H).
References
[1] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 43
[2] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 48; 49
[3] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 50-51
[4] Patent: WO2006/32851, 2006, A1. Location in patent: Page/Page column 41; 42
[5] Patent: WO2008/129280, 2008, A1. Location in patent: Page/Page column 46-47
5-Chloro-1H-pyrazole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-1H-pyrazole-3-carboxylic acid manufacturers
- Product
- 5-Chloro-1H-pyrazole-3-carboxylic acid 881668-70-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-11