5-BROMO-1-METHYL-2(1H)-PYRIDINONE

Product Name: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE
CAS No.: 81971-39-3
Chemical Name: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE
Synonyms: 5-bromo-1-methylpyridone;5-BroMo-1-Methylpyridin-2...;5-Bromo-1-methyl-pyridin-2-one;5-Bromo-1-methyl-2(1H)-pyridone;5-BroMo-1-Methyl-1H-pyridin-2-one;5-BROMO-1-METHYL-2(1H)-PYRIDINONE;2(1H)-Pyridinone, 5-bromo-1-methyl-;5-Bromo-1-methylpyridin-2(1H)-one;5-bromo-1-methyl-1,2-dihydropyridin-2-one;3-Bromo-1-methyl-6-oxo-1,6-dihydropyridine
CBNumber: CB91502436
Molecular Formula: C6H6BrNO
Formula Weight: 188.02
MOL File: 81971-39-3.mol

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5-BROMO-1-METHYL-2(1H)-PYRIDINONE Property

Melting point:: 62-63℃
Boiling point:: 258℃
Density: 1.664
Flash point:: 110℃
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: -0.41±0.62(Predicted)
color: White to Yellow to Orange
InChI: InChI=1S/C6H6BrNO/c1-8-4-5(7)2-3-6(8)9/h2-4H,1H3
InChIKey: HHVFVHIUOMMWRN-UHFFFAOYSA-N
SMILES: C1(=O)N(C)C=C(Br)C=C1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5482
Product name: 5-Bromo-1-methylpyridin-2(1H)-one
Purity: >98.0%(GC)
Packaging: 1g
Price: $103
Updated: 2025/07/31

TRC

Product number: B697615
Product name: 5-Bromo-1-methylpyridin-2(1H)-one
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B697615
Product name: 5-Bromo-1-methylpyridin-2(1H)-one
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB43007
Product name: 5-Bromo-1-methylpyridin-2(1H)-one
Packaging: 1g
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0046811
Product name: 5-Bromo-1-methyl-1,2-dihydropyridin-2-one
Purity: 98.67%
Packaging: 5g
Price: $90
Updated: 2021/12/16

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5-BROMO-1-METHYL-2(1H)-PYRIDINONE Chemical Properties,Usage,Production

Synthesis

13466-38-1

74-88-4

81971-39-3

5-Bromopyridin-2(1H)-one (8.6 g, 0.05 mol) was dissolved in THF (120 mL) at 0 °C and slowly added to a suspension of NaH (4.8 g, 0.2 mol) in THF (10 mL). The reaction mixture was stirred at 0 °C for 1 hour. Subsequently, iodomethane (35.5 g, 0.25 mol) was added dropwise to the mixture and stirring was continued for 3 hours at room temperature. After completion of the reaction, the reaction was quenched with saturated aqueous NH4Cl solution. The organic phase was separated and concentrated to give the crude product. The crude product was purified by column chromatography to afford 5-bromo-1-methylpyridin-2(1H)-one (8.9 g, 96.78% yield).1H NMR (CDCl3): δ= 3.5 (s, 3H), 6.52 (m, 1H), 7.32 (m, 1H), 7.45 (m, 1H).

References

[1] Patent: US2010/331320, 2010, A1. Location in patent: Page/Page column 56
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3649 - 3657
[3] Synlett, 2015, vol. 26, # 11, p. 1557 - 1562
[4] Patent: WO2013/49559, 2013, A1. Location in patent: Page/Page column 68
[5] Patent: WO2005/44195, 2005, A2. Location in patent: Page/Page column 40

5-BROMO-1-METHYL-2(1H)-PYRIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-1-METHYL-2(1H)-PYRIDINONE Suppliers

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View Lastest Price from 5-BROMO-1-METHYL-2(1H)-PYRIDINONE manufacturers

Career Henan Chemical Co

Product: 5-BROMO-1-METHYL-2(1H)-PYRIDINONE 81971-39-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-30

81971-39-3, 5-BROMO-1-METHYL-2(1H)-PYRIDINONERelated Search:

5-BROMO-1-(3-FLUOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 5-BROMO-2-OXO-1-[3-(TRIFLUOROMETHYL)BENZYL]-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 1-BENZYL-5-BROMO-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 3,5-DIBROMO-1,6-DIMETHYL-1H-PYRIDIN-2-ONE 5-BROMO-1-(2,4-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLIC ACID 3,5-DIBROMO-1-METHYL-1H-PYRIDIN-2-ONE 1-[(3-aminophenyl)methyl]-5-bromo-1,2-dihydropyridin-2-one 3-(5-bromo-2-oxo-1,2-dihydropyridin-1-yl)propanoic acid AURORA KA-4870 5-bromo-1-[(6-chloropyridin-3-yl)methyl]-1,2-dihydropyridin-2-one 4-(5-bromo-2-oxo-1,2-dihydropyridin-1-yl)butanoic acid AURORA KA-5587 (5-bromo-2-oxopyridin-1(2H)-yl)acetic acid AURORA KA-3484 5-bromo-1-(2-bromoethyl)pyridin-2(1H)-one 1-BENZYL-3,5-DIBROMO-6-METHYL-1H-PYRIDIN-2-ONE 5-BROMO-1-(2-HYDROXYETHYL)PYRIDIN-2(1H)-ONE ethyl 2-(5-bromo-2-oxo-1,2-dihydropyridin-1-yl)acetate

5-bromo-1-methyl-1,2-dihydropyridin-2-one

5-Bromo-1-methylpyridin-2(1<i>H</i>)-one

5-BROMO-1-METHYL-2(1H)-PYRIDINONE

5-BroMo-1-Methyl-1H-pyridin-2-one

5-BroMo-1-Methylpyridin-2...

3-Bromo-1-methyl-6-oxo-1,6-dihydropyridine

5-Bromo-1-methyl-2(1H)-pyridone

5-Bromo-1-methyl-pyridin-2-one

5-bromo-1-methylpyridone

2(1H)-Pyridinone, 5-bromo-1-methyl-

81971-39-3