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4-bromo-2,5-difluorobenzoic acid

Product Name
4-bromo-2,5-difluorobenzoic acid
CAS No.
28314-82-1
Chemical Name
4-bromo-2,5-difluorobenzoic acid
Synonyms
4-bromo-2,5-difluorobenzoic acid;2,5-Difluoro-4-broMobenzoic acid;Benzoic acid, 4-broMo-2,5-difluoro-;2-Propenoicacid,2-cyano-3-phenyl-,methylester,(5E)-;4-bromo-2,5-difluorobenzoic acid ISO 9001：2015 REACH
CBNumber
CB91559384
Molecular Formula
C7H3BrF2O2
Formula Weight
237
MOL File
28314-82-1.mol
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4-bromo-2,5-difluorobenzoic acid Property

Boiling point:
285.0±40.0 °C(Predicted)
Density 
1.872±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.70±0.10(Predicted)
form 
wooly powder
color 
Creamy peach
InChI
InChI=1S/C7H3BrF2O2/c8-4-2-5(9)3(7(11)12)1-6(4)10/h1-2H,(H,11,12)
InChIKey
YWZSTHLOAZTDFJ-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(F)=C(Br)C=C1F
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
B689698
Product name
4-Bromo-2,5-difluorobenzoicacid
Packaging
1g
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC501855
Product name
4-Bromo-2,5-difluorobenzoicacid
Packaging
1g
Price
$29
Updated
2021/12/16
SynQuest Laboratories
Product number
2621-B-50
Product name
4-Bromo-2,5-difluorobenzoic acid
Packaging
1g
Price
$32
Updated
2021/12/16
Apolloscientific
Product number
PC501855
Product name
4-Bromo-2,5-difluorobenzoicacid
Packaging
5g
Price
$95
Updated
2021/12/16
SynQuest Laboratories
Product number
2621-B-50
Product name
4-Bromo-2,5-difluorobenzoic acid
Packaging
5G
Price
$104
Updated
2021/12/16
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4-bromo-2,5-difluorobenzoic acid Chemical Properties,Usage,Production

Uses

4-Bromo-2,5-difluorobenzoic acid is a synthetic chemical compound that is widely used in scientific research. It is a versatile compound that can be used in many different laboratory experiments. It is also a fluorinated benzoic acid derivative and can be used as a reagent in a variety of organic and inorganic reactions.

Synthesis

Freshly titrated n-butyl lithium (27.0 ml, 1.39 M in hexanes) is added slowly (over about 30 minutes) to a -78°C solution of diethyl ether (90 ml) containing 1,4-dibromo-2,5-difluorobenzene (10.22 g, 0.038 mol). The resulting yellow solution is stirred at -78°C for 2 hours to give a yellow suspension. Several pellets (~10) of dry ice are added to the suspension, which is then allowed to warm slowly to room temperature as it degasses (approximately 40 minutes). The resulting suspension is acidified with a 1 M aqueous solution of hydrochloric acid (500 ml), and the product extracted with diethyl ether (5 x 200 ml). The combined organics are washed with water (4 x 100 ml) and filtered. The ether solution is concentrated to approximately 200 ml under reduced pressure, and the product extracted into a saturated aqueous solution of sodium bicarbonate (3 x 200 ml). The combined aqueous extracts are washed with methylene chloride (3 x 100 ml) and acidified with hydrochloric acid. The product is extracted with diethyl ether (3 x 200 ml), and the combined organic extracts washed with water (2 x 200 ml), dried over magnesium sulfate, and concentrated under reduced pressure to give 4-Bromo-2,5-difluorobenzoic acid as a pale yellow solid.Figure Synthesis of 4-Bromo-2,5-difluorobenzoic acid

4-bromo-2,5-difluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-bromo-2,5-difluorobenzoic acid Suppliers

China 131 India 2 United Kingdom 2 United States 8 Global 143
Accela ChemBio Inc.
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SynQuest Laboratories, Inc.
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Matrix Scientific
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View Lastest Price from 4-bromo-2,5-difluorobenzoic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Bromo-2-fluoro-6-nitrophenol 28314-82-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-05-10
Career Henan Chemical Co
Product
4-bromo-2,5-difluorobenzoic acid 28314-82-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

28314-82-1, 4-bromo-2,5-difluorobenzoic acidRelated Search:

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  • Benzoic acid, 4-broMo-2,5-difluoro-
  • 2,5-Difluoro-4-broMobenzoic acid
  • 4-bromo-2,5-difluorobenzoic acid ISO 9001：2015 REACH
  • 2-Propenoicacid,2-cyano-3-phenyl-,methylester,(5E)-
  • 28314-82-1