5-bromo-6-fluoropyridin-2-amine

Product Name: 5-bromo-6-fluoropyridin-2-amine
CAS No.: 944401-65-4
Chemical Name: 5-bromo-6-fluoropyridin-2-amine
Synonyms: 126033;5-bromo-6-fluoropyridin-2-amine;2-Amine-5-Bromo-6-Fluoropyridin;5-BROMO-6-FLUORO-2-PYRIDINAMINE;2-Amino-5-bromo-6-fluoropyridine;5-bromo-6-fluoropyridine-2-amine;6-AMino-3-broMo-2-fluoropyridine;2-Amine-5-Bromo-6-Fluoropyridine;2-Pyridinamine, 5-bromo-6-fluoro-;5-Bromo-6-fluoropyridin-2-ylamine
CBNumber: CB91559935
Molecular Formula: C5H4BrFN2
Formula Weight: 191
MOL File: 944401-65-4.mol

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5-bromo-6-fluoropyridin-2-amine Property

Boiling point:: 245℃
Density: 1.813
Flash point:: 102℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 1.25±0.10(Predicted)
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C5H4BrFN2/c6-3-1-2-4(8)9-5(3)7/h1-2H,(H2,8,9)
InChIKey: SJXWFNBZBXZDCL-UHFFFAOYSA-N
SMILES: C1(N)=NC(F)=C(Br)C=C1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B804205
Product name: 5-bromo-6-fluoropyridin-2-amine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B804205
Product name: 5-bromo-6-fluoropyridin-2-amine
Packaging: 500mg
Price: $265
Updated: 2021/12/16

Apolloscientific

Product number: PC910727
Product name: 6-Amino-3-bromo-2-fluoropyridine
Purity: 98%
Packaging: 250mg
Price: $218
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-B-0G
Product name: 6-Amino-3-bromo-2-fluoropyridine
Purity: 98%
Packaging: 250mg
Price: $240
Updated: 2021/12/16

Apolloscientific

Product number: PC910727
Product name: 6-Amino-3-bromo-2-fluoropyridine
Purity: 98%
Packaging: 1g
Price: $435
Updated: 2021/12/16

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5-bromo-6-fluoropyridin-2-amine Chemical Properties,Usage,Production

Uses

2-Amino-5-bromo-6-fluoropyridine is an organic intermediate, which can be prepared by bromination of 6-fluoropyridin-2-amine.

Synthesis

A solution of 6-fluoropyridin-2-amine (AlfaAesar, WardH, MA, 5.16 g, 46.0 mmol) in CAN (230 mL) was stirred at 0 ??C, then NBS (8.19 g, 46.0 mmol) was added as solvent. It was dissolved in CAN (100 mL) through the addition funnel within 30 min. After addition, the resulting green solution was stirred for another 30 min. The reaction mixture was then concentrated under reduced pressure and the residue was dissolved in DCM (20 mL) and adsorbed onto silica. Chromatographic purification (silica gel, 0-75% EtOAc in hexane solution) afforded 2-amino-5-bromo-6-fluoropyridine. White foam, yield 7.6 g, 39.8 mmol, 86%. 1HNMR (400 MHz, MeOH-d4) δ ppm 7.59 (1H, t, J=8.9 Hz), 6.32 (1H, dd, J=8.5, 1.5 Hz). m/z (ESI+) 191.0 (M+H)+.

5-bromo-6-fluoropyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-bromo-6-fluoropyridin-2-amine Suppliers

China 101 India 1 Ukraine 1 United States 11 Global 114

Zhengzhou HSH Science & Technology Co., Ltd.

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Energy Chemical

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
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9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
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View Lastest Price from 5-bromo-6-fluoropyridin-2-amine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-bromo-6-fluoropyridin-2-amine 944401-65-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

Career Henan Chemical Co

Product: 5-bromo-6-fluoropyridin-2-amine 944401-65-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

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5-bromo-6-fluoropyridine-2-amine

944401-65-4