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1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride

Product Name
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
CAS No.
2031-23-4
Chemical Name
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride
Synonyms
N-CHLOROPROPYL-N-METHYLPIPERAZINE;1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE HCL;1-(3-Chloropropyl)-4-methylpiperazine DiHCl;N-(3-Chloropropyl)-N'-methylpiperazine2hydrochloride;1-Methyl-4-(3-chloropropyl)piperazine dihydrochloride;1-(3-CHLORO-PROPYL)-4-METHYL-PIPERAZINE, HYDROCHLORIDE;1-(3-CHLOROPROPYL)-4-METHYL PIPERAZINE DIHYDROCHLORIDE;N-(3-CHLOROPROPYL)-N'-METHYL PIPERAZINE DIHYDROCHLORIDE;1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride ,98%;1-(3-chloropropyl)-4-methyl-Piperazine hydrochloride (1:2)
CBNumber
CB9156281
Molecular Formula
C8H19Cl3N2
Formula Weight
249.61
MOL File
2031-23-4.mol
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1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Property

Melting point:
255-257 °C (decomp)(Solv: ethanol (64-17-5))
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO, Methanol
form 
Solid
color 
White
CAS DataBase Reference
2031-23-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C379745
Product name
1-(3-Chloropropyl)-4-methylpiperazineDihydrochloride
Packaging
25g
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0015067
Product name
1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE DIHYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$162.75
Updated
2021/12/16
Apolloscientific
Product number
OR14748
Product name
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride
Packaging
5g
Price
$190
Updated
2021/12/16
Apolloscientific
Product number
OR14748
Product name
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride
Packaging
1g
Price
$48
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-P0
Product name
1-(3-Chloropropyl)-4-methylpiperazinedihydrochloride
Packaging
1g
Price
$53
Updated
2021/12/16
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1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Chemical Properties,Usage,Production

Uses

1-(3-Chloropropyl)-4-methylpiperazine Dihydrochloride

Synthesis

109-01-3

109-70-6

2031-23-4

N-methylpiperazine (30 mmol, 3.3 mL), 4 mL of 25% NaOH solution, and 40 mL of acetone were added to a 100 mL round-bottomed flask under ice bath cooling conditions. Subsequently, 1-bromo-3-chloropropane (30 mmol, 3 mL) was added and stirred in an ice bath until the reaction was complete, ensuring that all insoluble material was completely dissolved. The reaction mixture was allowed to stand at room temperature for 24 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. 20 mL of water was added to the residue, which was subsequently extracted with dichloromethane. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give a clarified oil. The reaction flask was placed in an ice bath and 50 mL of ethyl acetate was added. 2.5 mL of concentrated hydrochloric acid was added slowly and dropwise until a large amount of white solid was observed to be produced. During this process, the pH of the reaction system needed to be controlled to be about 2. The solvent was again removed by distillation under reduced pressure and the resulting solid was recrystallized with 100 mL of anhydrous ethanol. Finally, after filtration and drying, 3.3 g of white solid product was obtained as 1-(3-chloropropyl)-4-methylpiperazine dihydrochloride.

References

[1] Patent: CN105884699, 2016, A. Location in patent: Paragraph 0044; 0045
[2] Patent: WO2011/73092, 2011, A1. Location in patent: Page/Page column 29; 30

1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride Suppliers

China 105 Germany 3 India 4 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 10 United States 19 Global 145
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Koei Chemical Company, Ltd.
Tel
--
Fax
--
Country
Japan
ProdList
497
Advantage
65
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View Lastest Price from 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride manufacturers

Henan Fengda Chemical Co., Ltd
Product
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride 2031-23-4
Price
US $32.00-1.40/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-07
LY Global chemicals co.,ltd .
Product
1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride 2031-23-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%Min
Supply Ability
1000kg
Release date
2023-03-14
Shaanxi Dideu Medichem Co. Ltd
Product
1-(3-Chloropropyl)-4-Methylpiperazine dihydrochloride 2031-23-4
Price
US $0.00-0.00/KG
Min. Order
10g
Purity
99.0%+
Supply Ability
100 tons
Release date
2019-12-25

2031-23-4, 1-(3-Chloropropyl)-4-methylpiperazine dihydrochlorideRelated Search:

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  • 1-Methyl-4-(3-chloropropyl)piperazine dihydrochloride
  • 1-(3-Chloropropyl)-4-methylpiperazine DiHCl
  • 1-(3-CHLOROPROPYL)-4-METHYL PIPERAZINE DIHYDROCHLORIDE
  • 1-(3-CHLOROPROPYL)-4-METHYLPIPERAZINE HCL
  • 1-(3-CHLORO-PROPYL)-4-METHYL-PIPERAZINE, HYDROCHLORIDE
  • N-(3-Chloropropyl)-N'-methylpiperazine2hydrochloride
  • N-CHLOROPROPYL-N-METHYLPIPERAZINE
  • N-(3-CHLOROPROPYL)-N'-METHYL PIPERAZINE DIHYDROCHLORIDE
  • 1-(3-Chloropropyl)-4-methylpiperazine dihydrochloride ISO 9001：2015 REACH
  • 1-(3-chloropropyl)-4-methyl-Piperazine hydrochloride (1:2)
  • 2031-23-4
  • C8H17ClN22HCl
  • C8H19Cl3N2
  • C8H17ClN22ClH
  • C8H17ClN22HCI