(R)-(+)-1-(2-DIPHENYLPHOSPHINO-1-NAPHTHYL)ISOQUINOLINE Property

Melting point:

220-230 °C

Boiling point:

588.1±38.0 °C(Predicted)

storage temp. 

2-8°C

pka

4.45±0.30(Predicted)

form 

Crystalline Powder

color 

White to off-white

BRN 

6664856

Safety

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

37/39-26

WGK Germany 

3

HS Code 

29334990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(R)-(+)-1-(2-DIPHENYLPHOSPHINO-1-NAPHTHYL)ISOQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

(S)-QUINAP can be used as a ligand:

• In the asymmetric hydrosilylation of alkyl and α, β-unsaturated ketones in the presence of Fe(OAc)₂.??????
• For the synthesis of chiral organoboron compounds by copper-catalyzed β-borylation of α,β-unsaturated esters.

[Ir(cod)Cl]₂ treated with ligand (S)-QUINAP forms an iridium complex. This complex is used as a catalyst for the enantioselective hydrogenation of olefins. (S)-QUINAP–Rh complex can be employed as a catalyst in enantioselective hydroboration/oxidation of perfluoroalkenes.

General Description

(S)-QUINAP is a bidentate ligand used in catalytic asymmetric hydroboration, hydrogenation, oxidation, and allylic alkylation reactions.