H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2

Product Name: H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2
CAS No.: 138764-85-9
Chemical Name: H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2
Synonyms: PACAP 1-38;GKRYKQRVKNKYKQRVKNK-NH2;PACAP (31-38) (HUMAN, OVINE, RAT);TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2;PACAP-38?(31-38),?human,?mouse,?rat;H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2;PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE 1-38;PACAP-38 (31-38) (HUMAN, CHICKEN, MOUSE, OVINE, PORCINE, RAT);PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (31-38), HUMAN, OVINE, RAT;PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (31-38) (HUMAN, OVINE, RAT)
CBNumber: CB9169513
Molecular Formula: C47H83N17O11
Formula Weight: 1062.27
MOL File: 138764-85-9.mol

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H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 Property

Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: -15°C
form: Solid
pka: 9.96±0.15(Predicted)
color: White to off-white
Sequence: Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1186
Product name: PACAP1-38
Purity: ≥95%(HPLC)
Packaging: 100U
Price: $208
Updated: 2021/12/16

Usbiological

Product number: 256148
Product name: PACAP 1-38
Packaging: 100ug
Price: $460
Updated: 2021/12/16

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H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 Chemical Properties,Usage,Production

Uses

PACAP-38 (31-38), human, mouse, rat is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat elevates cytosolic Ca2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat can be used for neurotrophic and neuroprotective research[1][2][3].

Biological Activity

Endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP) but with a greater potency for stimulation of adenylyl cyclase.

References

[1] Moody TW, et, al. PAC1 regulates receptor tyrosine kinase transactivation in a reactive oxygen species-dependent manner. Peptides. 2019 Oct;120:170017. DOI:10.1016/j.peptides.2018.09.005
[2] Kojro E, et, al. The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. FASEB J. 2006 Mar;20(3):512-4. DOI:10.1096/fj.05-4812fje
[3] Braas KM, et, al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 De DOI:10.1111/j.1749-6632.1996.tb17484.x

H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 Suppliers

China 72 United Kingdom 2 United States 9 Global 83

3B Pharmachem (Wuhan) International Co.,Ltd.

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View Lastest Price from H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 manufacturers

Career Henan Chemical Co

Product: H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 138764-85-9
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

138764-85-9, H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2Related Search:

H-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 H-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2 PACAP 1-27 PACAP38 DVAHEILNEAYRKVLDQLSARKYLQSMVA H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-LYS(BIOTIN)-NH2 PACAP (1-38), frog PACAP 6-38 H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 L(+)-Arginine Argon H-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2 ([125I]-TYR)-PACAP-38 (31-38) (HUMAN, CHICKEN, MOUSE, OVINE, PORCINE, RAT) H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2

PACAP 1-38

PACAP (31-38) (HUMAN, OVINE, RAT)

PACAP-38 (31-38) (HUMAN, CHICKEN, MOUSE, OVINE, PORCINE, RAT)

PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (31-38), HUMAN, OVINE, RAT

PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (31-38) (HUMAN, OVINE, RAT)

PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE 1-38

PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE-38 (31-38) (HUMAN, CHICKEN, MOUSE, OVINE, PORCINE, RAT)

TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2

PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2: FTDSYSRYRKQMAVKKYLAAVL0NH2

Pituitary Adenylate Cyclase Activating Polypeptide-38 (31-38) (huMan, chicken, Mouse, ovine, porcine, rat) , Pituitary Adenylate Cyclase Activating Polypeptide-38 (31-38) (huMan, chicken, Mouse, ovine, porcine, rat)

H-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2

PACAP-38?(31-38),?human,?mouse,?rat

L-Lysinamide, L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparaginyl- (9CI)

L-Lysinamide,L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparaginyl-

GKRYKQRVKNKYKQRVKNK-NH2

138764-85-9

C47H83N17O11