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PACAP 1-27

Product Name
PACAP 1-27
CAS No.
127317-03-7
Chemical Name
PACAP 1-27
Synonyms
ovine;M-PACAP;PACAP-27;PACAP 1-27;PACAP-27 (human;PACAP (1-27) AMIDE;Human PACAP-(1-27);PACAP (1-27) (human;PACAP 27 AMIDE, OVINE;neurohypophysical hormone
CBNumber
CB7101106
Molecular Formula
C142H224N40O39S
Formula Weight
3147.61
MOL File
127317-03-7.mol
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PACAP 1-27 Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
solid
color 
white
Water Solubility 
Soluble to 1 mg/ml in water
InChI
InChI=1/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/s3
InChIKey
RZGBUJXSKLDAFE-XVTUQGJWNA-N
SMILES
[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@@H](C)CC)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC1N=CNC=1)CC1=CC=CC=C1)CC1C=CC(O)=CC=1)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)N)CC(C)C)CC1C=CC(O)=CC=1)CC1=CC=C(O)C=C1 |&1:0,4,15,21,25,31,39,40,46,50,51,62,70,76,102,113,122,131,139,144,151,160,169,173,181,186,191,198,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
05-23-2151
Product name
PACAP 27 Amide, Ovine
Purity
Increases cAMP levels in a dose-dependent manner (EC?? = 4.7 nM).
Packaging
0.5MG
Price
$405
Updated
2024/03/01
Sigma-Aldrich
Product number
05-23-2151
Product name
PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem
Purity
Increases cAMP levels in a dose-dependent manner (EC?? = 4.7 nM).
Packaging
.5mg
Price
$390
Updated
2023/01/07
Alfa Aesar
Product number
J66752
Product name
PACAP (1-27), human, ovine, rat
Packaging
1mg
Price
$428
Updated
2023/06/20
Alfa Aesar
Product number
J66752
Product name
PACAP (1-27), human, ovine, rat
Packaging
0.5mg
Price
$200
Updated
2021/12/16
Tocris
Product number
1183
Product name
PACAP1-27
Packaging
100U
Price
$161
Updated
2021/12/16
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PACAP 1-27 Chemical Properties,Usage,Production

Uses

Pituitary Adenylate Cyclase-Activating Polypeptide 1-27 (PACAP 1-27) is a neuropeptide that stimulates adenylyl cyclase.

Biological Functions

PACAP 1-27 is an endogenous neuropeptide and is the C-terminally truncated form of PACAP 38. PACAP 27 has considerable homology with vasoactive intestinal peptide (VIP) but is >100 fold more potent than VIP as an agonist of the PAC1 receptor. PACAP 27 functions in the control of anterior pituitary hormone secretion, vasodilation, adrenaline secretion, insulin secretion and immunosuppression.

Biological Activity

PACAP 1-27, also known as PACAP 27 Amide, is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase.

storage

Store at -20°C

PACAP 1-27 Preparation Products And Raw materials

Raw materials

Oxytocin Nisin Α-protein

Preparation Products

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PACAP 1-27 Suppliers

China 90 Europe 1 France 1 Germany 4 Japan 1 Switzerland 2 United Kingdom 2 United States 17 Global 118
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
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View Lastest Price from PACAP 1-27 manufacturers

Shanghai Getian Industrial Co., LTD
Product
PACAP 1-27 127317-03-7
Price
US $23.00-17.00/box
Min. Order
1box
Purity
99%
Supply Ability
100000box
Release date
2024-05-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
127317-03-7 127317-03-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
127317-03-7 127317-03-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

127317-03-7, PACAP 1-27Related Search:

PACAP 6-38 PACAP38 PITUITARY ADENYLATE CYCLASE ACTIVATING DL-THYROXINE HLH Pregnant mare serum gonadotropin Follicle stimulating hormone Follicle-stimulating hormone TSH Corticotropin Testosterone Parathyroid CORTISONE Hydrocortisone Inositol Calcitonin Vasopressin H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-LYS(BIOTIN)-NH2

  • HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2
  • HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2
  • H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2
  • [ARG14,20,21, LEU16] PACAP (1-27), HUMAN, OVINE, RAT
  • [ARG14,20,21, LEU16] PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (1-27), HUMAN, OVINE, RAT
  • ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE-27 OVINE
  • ADENYLATE CYCLASE ACTIVATING PEPTIDE-27
  • pituitary adenylate cyclase activating*polypeptid
  • pituitary adenylate cyclase activating polypeptide-27 ovine
  • powdered posterior pitultary
  • HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-ARG-GLN-LEU-ALA-VAL-ARG-ARG-TYR-LEU-ALA-ALA-VAL-LEU-NH2
  • HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-GLY-LYS-ARG-TYR-LYS-GLN-ARG-VAL-LYS-ASN-LYS-NH2: HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
  • PACAP-38 (1-27) aMide (huMan, Mouse, ovine, porcine, rat), Pituitary Adenylate Cyclase Activating Polypeptide-27 (huMan, Mouse, ovine, porcine, rat)
  • PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27 AMIDE, OVINE
  • PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE-27 (HUMAN, MOUSE, OVINE, PORCINE, RAT)
  • PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE
  • PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE 1-27
  • PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (1-27) AMIDE (HUMAN, OVINE, RAT)
  • PITUARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27 (HUMAN, 1-27 AMIDE) OVINE, RAT
  • PITUITARY ADENYLATE CYCLASE-ACTIVATING PEPTIDE (1-27)
  • PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (1-27), HUMAN, OVINE, RAT
  • PACAP-27
  • PACAP-38 (1-27) AMIDE (HUMAN, MOUSE, OVINE, PORCINE, RAT)
  • PACAP 27 AMIDE, OVINE
  • PACAP27 (HUMAN, 1-27 AMIDE) (OVINE, RAT)
  • PACAP-27 (HUMAN, MOUSE, OVINE, PORCINE, RAT)
  • PACAP-27 (HUMAN, OVINE, RAT)
  • PACAP 1-27
  • PACAP (1-27) AMIDE
  • PACAP (1-27), AMIDE, HUMAN, OVINE, RAT
  • PACAP (1-27), HUMAN, OVINE, RAT
  • PACAP (1-27) (HUMAN, SHEEP, RAT)
  • PACAP-PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (HUMAN, OVINE, RAT)
  • M-PACAP
  • PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem
  • L-Leucinamide, L-histidyl-L-seryl-L-α-aspartylglycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-
  • Pituitary adenylatecyclase-activating peptide-27 (human) (9CI)
  • H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2 USP/EP/BP
  • ovine
  • PACAP-27 (human
  • porcine rat) trifluoroacetate salt
  • Human PACAP-(1-27)
  • H-HIS-SER-ASP-GLY-ILE-PHE-THR-ASP-SER-TYR-SER-ARG-TYR-ARG-LYS-GLN-MET-ALA-VAL-LYS-LYS-TYR-LEU-ALA-ALA-VAL-LEU-NH2
  • neurohypophysical hormone
  • PACAP (1-27) (human
  • Pacpa-27 (human, mouse, ovine, porcine, rat)
  • 127317-03-7
  • C43H66O12N12S2
  • C142H224N40O39S
  • Cyclic Nucleotide Metabolism
  • G Proteins and Cyclic Nucleotides
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Adenylyl Cyclase Activators
  • Peptide
  • VIP and PACAP receptor