ChemicalBook > CAS DataBase List > PACAP 1-27
PACAP 1-27
- Product Name
- PACAP 1-27
- CAS No.
- 127317-03-7
- Chemical Name
- PACAP 1-27
- Synonyms
- ovine;M-PACAP;PACAP-27;PACAP 1-27;PACAP-27 (human;PACAP (1-27) AMIDE;Human PACAP-(1-27);PACAP (1-27) (human;PACAP 27 AMIDE, OVINE;neurohypophysical hormone
- CBNumber
- CB7101106
- Molecular Formula
- C142H224N40O39S
- Formula Weight
- 3147.61
- MOL File
- 127317-03-7.mol
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PACAP 1-27 Property
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- form
- solid
- color
- white
- Water Solubility
- Soluble to 1 mg/ml in water
- InChI
- InChI=1/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/s3
- InChIKey
- RZGBUJXSKLDAFE-XVTUQGJWNA-N
- SMILES
- [C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@@H](C)CC)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC1N=CNC=1)CC1=CC=CC=C1)CC1C=CC(O)=CC=1)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)N)CC(C)C)CC1C=CC(O)=CC=1)CC1=CC=C(O)C=C1 |&1:0,4,15,21,25,31,39,40,46,50,51,62,70,76,102,113,122,131,139,144,151,160,169,173,181,186,191,198,r|
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 05-23-2151
- Product name
- PACAP 27 Amide, Ovine
- Purity
- Increases cAMP levels in a dose-dependent manner (EC?? = 4.7 nM).
- Packaging
- 0.5MG
- Price
- $405
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 05-23-2151
- Product name
- PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem
- Purity
- Increases cAMP levels in a dose-dependent manner (EC?? = 4.7 nM).
- Packaging
- .5mg
- Price
- $390
- Updated
- 2023/01/07
Alfa Aesar
- Product number
- J66752
- Product name
- PACAP (1-27), human, ovine, rat
- Packaging
- 1mg
- Price
- $428
- Updated
- 2023/06/20
Alfa Aesar
- Product number
- J66752
- Product name
- PACAP (1-27), human, ovine, rat
- Packaging
- 0.5mg
- Price
- $200
- Updated
- 2021/12/16
Tocris
- Product number
- 1183
- Product name
- PACAP1-27
- Packaging
- 100U
- Price
- $161
- Updated
- 2021/12/16
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PACAP 1-27 Chemical Properties,Usage,Production
Uses
Pituitary Adenylate Cyclase-Activating Polypeptide 1-27 (PACAP 1-27) is a neuropeptide that stimulates adenylyl cyclase.
Biological Functions
PACAP 1-27 is an endogenous neuropeptide and is the C-terminally truncated form of PACAP 38. PACAP 27 has considerable homology with vasoactive intestinal peptide (VIP) but is >100 fold more potent than VIP as an agonist of the PAC1 receptor. PACAP 27 functions in the control of anterior pituitary hormone secretion, vasodilation, adrenaline secretion, insulin secretion and immunosuppression.
Biological Activity
PACAP 1-27, also known as PACAP 27 Amide, is an endogenous neuropeptide showing considerable homology with vasoactive intestinal peptide (VIP). Potently stimulates adenylyl cyclase.
storage
Store at -20°C
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View Lastest Price from PACAP 1-27 manufacturers
Shanghai Getian Industrial Co., LTD
- Product
- PACAP 1-27 127317-03-7
- Price
- US $23.00-17.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 100000box
- Release date
- 2024-05-07
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 127317-03-7 127317-03-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 127317-03-7 127317-03-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
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