4ALPHA-PHORBOL 12,13-DIDECANOATE

Product Name: 4ALPHA-PHORBOL 12,13-DIDECANOATE
CAS No.: 27536-56-7
Chemical Name: 4ALPHA-PHORBOL 12,13-DIDECANOATE
Synonyms: 4a-PDD;4ALPHA-PDD;4α-Phorbol 12;13-didecanoate;4alphaPDD,4alpha PDD;-Phorbol12,13-didecanoate;4α-phorbol 12-13-dicaprinate;4a-Phorbol-12,13-didecanoate;4α-Phorbol 12,13-didecanoate;4alpha-Phorbol 12,13-dideconate
CBNumber: CB9171479
Molecular Formula: C40H64O8
Formula Weight: 672.93
MOL File: 27536-56-7.mol

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4ALPHA-PHORBOL 12,13-DIDECANOATE Property

storage temp.: -20°C
solubility: DMSO: soluble
form: solid
color: white
BRN: 2514324

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Safety

Hazard Codes: T+
Risk Statements: 26/27/28-40-43
Safety Statements: 36/37/39-45
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
F: 8-10
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 524394
Product name: 4α-Phorbol-12,13-didecanoate
Packaging: 1mg
Price: $125
Updated: 2024/03/01

Sigma-Aldrich

Product number: 524394
Product name: 4α-Phorbol-12,13-didecanoate
Packaging: 5mg
Price: $476
Updated: 2024/03/01

Cayman Chemical

Product number: 20446
Product name: 4α-Phorbol 12,13-didecanoate
Purity: ≥99%
Packaging: 1mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 20446
Product name: 4α-Phorbol 12,13-didecanoate
Purity: ≥99%
Packaging: 5mg
Price: $425
Updated: 2024/03/01

Sigma-Aldrich

Product number: P8014
Product name: 4α-Phorbol 12,13-didecanoate
Purity: solid
Packaging: 1mg
Price: $204
Updated: 2024/03/01

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4ALPHA-PHORBOL 12,13-DIDECANOATE Chemical Properties,Usage,Production

Uses

4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist:

to study its effects on Madin-Darby canine kidney (MDCK) cells
to study its effects on Ca²⁺ influx in mice fallopian tubal cells
to study its effects on hind paw swelling in mice

Definition

ChEBI: 4alpha-phorbol 12,13-didecanoate is a phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted to the corresponding decanoate esters. A Trpv4-specific ligand. It has a role as a TRPV4 agonist. It is a phorbol ester, a decanoate ester, a tertiary alpha-hydroxy ketone, a diester and a primary allylic alcohol.

Biochem/physiol Actions

4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.

4ALPHA-PHORBOL 12,13-DIDECANOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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4ALPHA-PHORBOL 12,13-DIDECANOATE Suppliers

China 26 Germany 1 South Korea 1 Switzerland 2 United Kingdom 2 United States 7 Global 39

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27536-56-7, 4ALPHA-PHORBOL 12,13-DIDECANOATERelated Search:

Citronellol (R)-(+)-BETA-CITRONELLOL Dihydromyrcene 1-Methylcyclohexanol CYCLOHEPTENE (-)-CITRONELLAL Isoamyl butyrate (R)-(+)-1,2-OCTANEDIOL 2,4-DIMETHYL-4-PENTEN-2-OL CIS-4-DECEN-1-OL 2-ETHYLHEXYL BUTYRATE N-CAPRIC ACID N-HEPTYL ESTER N-CAPRYLIC ACID ISOBUTYL ESTER CYCLODODECENE 2-METHYLCARBAZOLE 2-ETHYLHEXYL PELARGONATE RHODINYL ACETATE 2,4-dimethylnonan-4-ol

4ALPHA-PDD

4ALPHA-PHORBOL 12-13-DICAPRINATE

4ALPHA-PHORBOL 12,13-DIDECANOATE

4a-Phorbol-12,13-didecanoate

4A-PHORBOL 12,13-DIDECANOATE WEAK PROTEI N KINASE C

4α-phorbol 12-13-dicaprinate

4A-PHORBOL 12,13-DIDECANOATE, 99+%

phorbol (4alpha-) 12,13-didecanoate

4α-Phorbol 12-13-dicaprinate, 4αPDD

4alpha-Phorbol 12,13-dideconate

Decanoic acid, 1,1A,1B,4,4A,5,7A,7B,8,9-decahydro-4A,7B-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-E)azulene-9,9A-diyl ester, (1ar-(1aalpha,1bbeta,4aalpha,7aalpha,7balpha,8alpha,9beta,9aalpha))-

4-alpha-Phorbol 12,13-Didecanoate >99%

4α-Phorbol 12,13-Didecanoate, >99%

4a-PDD

4α-Phorbol-12,13-didecanoate - CAS 27536-56-7 - Calbiochem

Decanoic acid, 1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl] ester

4α-Phorbol 12,13-didecanoate

-Phorbol12,13-didecanoate

13-didecanoate

4α-Phorbol 12

4alphaPDD,4alpha PDD

4alpha-Phorbol 12,13-didecanoate solid

27536-56-7

C40H64O8

Kinase/Phosphatase Biology

Serine/Threonine Kinase Activators

Protein Kinase C (PKC)

Cell Signaling and Neuroscience

Cell Biology

BioChemical

metabolite