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α,α-Difluorophenylacetic acid

Product Name
α,α-Difluorophenylacetic acid
CAS No.
360-03-2
Chemical Name
α,α-Difluorophenylacetic acid
Synonyms
Difluorophenylacetic aci;DIFLUORO(PHENYL)ACETIC ACID;2,3-DIFLUUOROPHENYL ACETIC;α,α-Difluorophenylaceticaci;A,A-DIFLUOROPHENYLACETIC ACID;α,α-Difluorophenylacetic acid;α,α-Difluorobenzeneacetic acid;α,α-Difluorobenzeneacetic acid;2,3-DIFLUUOROPHENYL ACETIC ACID;2,2-DIFLUORO-2-PHENYLACETIC ACID
CBNumber
CB9176818
Molecular Formula
C8H6F2O2
Formula Weight
172.13
MOL File
360-03-2.mol
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α,α-Difluorophenylacetic acid Property

Melting point:
65-75 °C
Boiling point:
0°C
Density 
1.338±0.06 g/cm3(Predicted)
Flash point:
0°C
storage temp. 
Refrigerator, Under inert atmosphere
solubility 
Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form 
Solid
pka
1.04±0.10(Predicted)
color 
White to Pale Yellow
CAS DataBase Reference
360-03-2(CAS DataBase Reference)
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Safety

Hazard Codes 
C,Xi,Xn
Risk Statements 
36/37/38
Safety Statements 
26-36-36/37-36/37/39
RIDADR 
UN3261
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
708186
Product name
α,α-Difluorophenylacetic acid
Purity
97%
Packaging
1g
Price
$71.1
Updated
2024/03/01
Alfa Aesar
Product number
H26028
Product name
alpha,alpha-Difluorophenylacetic acid, 99%
Packaging
250mg
Price
$55.65
Updated
2024/03/01
TRC
Product number
D447148
Product name
2,2-Difluoro-2-phenylaceticAcid
Packaging
100mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
018321
Product name
alpha,alpha-Difluorophenylacetic acid
Packaging
1g
Price
$16
Updated
2021/12/16
SynQuest Laboratories
Product number
2721-3-16
Product name
2,2-Difluoro-2-phenylacetic acid
Packaging
1g
Price
$25
Updated
2021/12/16
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α,α-Difluorophenylacetic acid Chemical Properties,Usage,Production

Description

α,α-Difluorophenylacetic acid is a phenylacetic acid with two fluorides on the benzylic carbon. The inductive effect of the difluoromethyl group increases the acidity of α,α-difluorophenylacetic acid. α,α-difluorophenylacetic acid and 2-arylbenzoimidazoles could be used as reaction substrates to synthesise difluoroarymethyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones through radical cascade cyclization[1].

Chemical Properties

white to light yellow crystal powde

References

[1] Kaixia Sui, Yuting Leng* and Yangjie Wu*. “Synthesis of Difluoroarymethyl-Substituted Benzimidazo[2,1-a]isoquinolin-6(5H)-ones under Mild Conditions.” ACS Omega 8 8 (2023): 7517–7528.

α,α-Difluorophenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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α,α-Difluorophenylacetic acid Suppliers

China 125 Europe 3 Germany 2 India 2 Italy 1 Slovakia 1 Ukraine 2 United Kingdom 7 United States 21 Global 164
J & K SCIENTIFIC LTD.
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Syntechem Co.,Ltd
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View Lastest Price from α,α-Difluorophenylacetic acid manufacturers

Hebei Mojin Biotechnology Co.,Ltd
Product
α,α-Difluorophenylacetic acid 360-03-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-23
Career Henan Chemical Co
Product
α,α-Difluorophenylacetic acid 360-03-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

360-03-2, α,α-Difluorophenylacetic acidRelated Search:

3,4-Difluorophenylacetic acid 98%,3,4-DIFLUOROPHENYLACETIC ACID 2,4-Difluorophenylacetic acid 97%,2,4-DIFLUOROPHENYLACETIC ACID à-hydroxy-2,3-difluorophenylacetic acid,alpha-Hydroxy-2,3-difluorophenylacetic acid à-hydroxy-2,6-difluorophenylacetic acid,alpha-Hydroxy-2,6-difluorophenylacetic acid 2,6-Difluorophenylacetic acid 97%,2,6-DIFLUOROPHENYLACETIC ACID 2,3-Difluorophenylacetic acid 3,4-DIFLUOROPHENYLACETIC ACID METHYL ESTER 3,5-DIFLUOROPHENYLACETIC ACID,3,5-Difluorophenylacetic acid 99% A,A-DIFLUOROPHENYLACETIC ACID ETHYL ESTER,DIFLUOROPHENYLACETIC ACID ETHYL ESTER 2,5-DIFLUOROPHENYLACETIC ACID,2,5-Difluorophenylacetic acid 97% 3-CHLORO-2,4-DIFLUOROPHENYLACETIC ACID 3-CHLORO-2,6-DIFLUOROPHENYLACETIC ACID alpha-Hydroxy-2,4-difluorophenylacetic acid,à-hydroxy-2,4-difluorophenylacetic acid alpha-Hydroxy-3,4-difluorophenylacetic acid,à-hydroxy-3,4-difluorophenylacetic acid à-hydroxy-2,5-difluorophenylacetic acid 4-CHLORO-2,6-DIFLUOROPHENYLACETIC ACID à-hydroxy-3,5-difluorophenylacetic acid,alpha-Hydroxy-3,5-difluorophenylacetic acid Phenylacetic acid

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