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2-Adamantanamine hydrochloride

Product Name
2-Adamantanamine hydrochloride
CAS No.
10523-68-9
Chemical Name
2-Adamantanamine hydrochloride
Synonyms
2-AdamantylamineHCl;IFLAB-BB F1928-0024;2-AMINOADAMANTANEHCL;2-ADAMANTANAMINE HCL;2-admantylamine hydrochloride;2-Adamantanamin hydrochloride;2-ADAMANTANAMINE HYDROCHLORIDE;2-ADAMANTYLAMINE HYDROCHLORIDE;adamantan-2-amine hydrochloride;2-AMINOADAMANTANE HYDROCHLORIDE
CBNumber
CB9179738
Molecular Formula
C10H18ClN
Formula Weight
187.71
MOL File
10523-68-9.mol
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2-Adamantanamine hydrochloride Property

Melting point:
>300 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Crystalline Powder
color 
White
Water Solubility 
soluble
BRN 
4297901
InChI
InChI=1/C10H17N.ClH/c11-10-8-2-6-1-7(4-8)5-9(10)3-6;/h6-10H,1-5,11H2;1H/t6-,7+,8-,9+,10?;
InChIKey
WLDWDRZITJEWRJ-ZDAMNCSYNA-N
SMILES
C1(N)[C@@]2([H])C[C@]3([H])C[C@]([H])(C2)C[C@@]1([H])C3.Cl |&1:2,5,8,12,r|
CAS DataBase Reference
10523-68-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-36/37/39-22
WGK Germany 
3
RTECS 
AU4375100
10
HazardClass 
IRRITANT
HS Code 
29213000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
153818
Product name
2-Adamantylamine hydrochloride
Purity
99%
Packaging
5g
Price
$117
Updated
2024/03/01
Sigma-Aldrich
Product number
153818
Product name
2-Adamantylamine hydrochloride
Purity
99%
Packaging
25g
Price
$136.8
Updated
2024/03/01
TCI Chemical
Product number
A0718
Product name
2-Adamantanamine Hydrochloride
Purity
>99.0%(T)
Packaging
5g
Price
$94
Updated
2024/03/01
TCI Chemical
Product number
A0718
Product name
2-Adamantanamine Hydrochloride
Purity
>99.0%(T)
Packaging
25g
Price
$324
Updated
2024/03/01
Alfa Aesar
Product number
A17140
Product name
2-Adamantanamine hydrochloride, 98+%
Packaging
1g
Price
$26.65
Updated
2024/03/01
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2-Adamantanamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2?-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Uses

2-Adamantanamine Hydrochloride can be used to prepare CD73 inhibitors to treat CD73-associated diseases, including cancer and immune-related disorders.

General Description

The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied.

Purification Methods

The free amine in Et2O, liberated by the action of alkali in H2O, is dried over KOH, filtered, evaporated and sublimed at 110o/12torr, m 230-236o. The base is dissolved in EtOH, sufficient ethanolic HCl is added dropwise and crystallised by the addition of Et2O. Dry it in vacuo. [Stetter et al. Justus Liebigs Ann Chem 658 151 1962].

2-Adamantanamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Adamantanamine hydrochloride Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 2-Adamantanamine hydrochloride manufacturers

Longyan Tianhua Biological Technology Co., Ltd
Product
2-Adamantanamine hydrochloride 10523-68-9
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2020-11-16
Career Henan Chemical Co
Product
2-Adamantanamine hydrochloride 10523-68-9
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10TON
Release date
2018-12-18

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