ChemicalBook > CAS DataBase List > 3,6,9-TRIOXAUNDECANEDIOIC ACID

3,6,9-TRIOXAUNDECANEDIOIC ACID

Product Name
3,6,9-TRIOXAUNDECANEDIOIC ACID
CAS No.
13887-98-4
Chemical Name
3,6,9-TRIOXAUNDECANEDIOIC ACID
Synonyms
2,2'-((oxybis(ethane-2,1-diyl))bis(oxy))diacetic acid;TRIOXAUNDECANEDIOIC ACID;TUDS;TUDA;SKL081;CAS_13887-98-4;Einecs 237-655-9;Tetraglycolic acid;CH2COOH-PEG3-CH2COOH;CH2COOH-PEG2-CH2COOH
CBNumber
CB9181629
Molecular Formula
C8H14O7
Formula Weight
222.19
MOL File
13887-98-4.mol
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3,6,9-TRIOXAUNDECANEDIOIC ACID Property

Boiling point:
443.7±30.0 °C(Predicted)
Density 
1.3 g/mL at 20 °C(lit.)
vapor pressure 
0Pa at 20℃
refractive index 
n20/D 1.470(lit.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Solid-Liquid Mixture
pka
3.09±0.10(Predicted)
color 
Off-white to yellow
PH
1.8 (100g/l, H2O)
BRN 
1962084
InChI
InChI=1S/C8H14O7/c9-7(10)5-14-3-1-13-2-4-15-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)
InChIKey
HJZZQNLKBWJYPD-UHFFFAOYSA-N
SMILES
O(CCOCC(O)=O)CCOCC(O)=O
LogP
-2.56 at 25℃
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26-39
RIDADR 
1760
WGK Germany 
1
HazardClass 
8
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
92893
Product name
3,6,9-Trioxaundecanedioic acid
Purity
technical, ≥70% (T)
Packaging
50ml
Price
$232
Updated
2025/07/31
Sigma-Aldrich
Product number
92893
Product name
3,6,9-Trioxaundecanedioic acid
Purity
technical, ≥70% (T)
Packaging
250ml
Price
$388.5
Updated
2025/07/31
Activate Scientific
Product number
AS103919
Product name
HOOCCH2O-PEG2-CH2COOH
Purity
95+%
Packaging
25g
Price
$198
Updated
2021/12/16
AK Scientific
Product number
2158AQ
Product name
2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diaceticacid
Packaging
5g
Price
$347.6
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG2030
Product name
TUDA
Packaging
100g
Price
$391.5
Updated
2021/12/16
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3,6,9-TRIOXAUNDECANEDIOIC ACID Chemical Properties,Usage,Production

Description

PEG3-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Flammability and Explosibility

Not classified

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

3,6,9-TRIOXAUNDECANEDIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,6,9-TRIOXAUNDECANEDIOIC ACID Suppliers

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View Lastest Price from 3,6,9-TRIOXAUNDECANEDIOIC ACID manufacturers

Shanghai Rlavie Technology Co ltd
Product
3,6,9-Trioxaundecanedioic acid 13887-98-4
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-17
Career Henan Chemical Co
Product
3,6,9-TRIOXAUNDECANEDIOIC ACID 13887-98-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-05

13887-98-4, 3,6,9-TRIOXAUNDECANEDIOIC ACIDRelated Search:


  • O,O'-OXYDIETHYLENE-DIGLYCOLIC ACID
  • 3,6,9-TRIOXAUNDECANEDIOIC ACID
  • CH2COOH-PEG3-CH2COOH
  • HOOCCH2O-PEG2-CH2COOH
  • 3,6,9-Trioxaundecanedioic acid technical
  • TUDS
  • trioxaundecanedoicacid
  • 2,2'-[oxybis(2,1-ethanediyloxy)]bisacetic acid
  • TRIOXAUNDECANEDIOIC ACID
  • 3,6,9-Trioxaundecanedioic acid (TUDS)
  • Acetic acid, 2,2-oxybis(2,1-ethanediyloxy)bis-
  • 2,2′-(Oxybis(2,1-ethandiyloxy))bisessigsure
  • 3,6,9-Trioxa-1,11-undecanedioic acid
  • 3,6,9-Trioxaundecandioic acid
  • TUDA
  • [Oxybis(ethyleneoxy)]bis(acetic acid)
  • [Oxybis(ethyleneoxy)]diacetic acid
  • 2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid
  • 3,6,9-Trioxaundecadioic acid
  • Diethylenetrioxydiacetic acid
  • Acetic acid, (oxybis(2,1-ethanediyloxy))bis-
  • Einecs 237-655-9
  • 2,2'-((oxybis(ethane-2,1-diyl))bis(oxy))diacetic acid
  • [2-{2-(Carboxymethoxy)ethoxy}ethoxy]acetic acid
  • 2-(2-(Carboxymethoxy)ethoxy)ethoxyacetic acid
  • Diethylene glycol bis(carboxymethyl ether)
  • Tetraglycolic acid
  • 3,6,9-Trioxaundecanedioic acid technical, >=70% (T)
  • CH2COOH-PEG2-CH2COOH
  • 2,2'-[Oxybis(2,1-ethanediyloxy)] bisacetic acid for synthesis
  • CAS_13887-98-4
  • Bis-PEG3-acetic acid
  • COOH-CH2-PEG2-CH2-COOH
  • SKL081
  • 2-[2-[2-(Carboxymethoxy)ethoxy]ethoxy]acetic acid
  • HOOCCH2O-PEG2-CH2COOH/3,6,9-Trioxa-undecanedioic acid
  • 3,6,9 trioxundecanedioic acid
  • 3,6,9-Trioxaundecanedioic Acid(containing Salt)
  • Acetic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
  • tetraglycolic acid, 3,6,9-Trioxaundecanedioic acid
  • 3,6,9-Trioxaundecanedioic Acid - [X62144]
  • 13887-98-4
  • C8H14O7
  • Functionalized Oligoethylene Glycol
  • Peptide PEGylation
  • Peptide Synthesis
  • Specialty Synthesis
  • Heterocyclic Compounds
  • peg