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ChemicalBook > CAS DataBase List > HUMAN IL-15

HUMAN IL-15

Description Source Background
Product Name
HUMAN IL-15
Chemical Name
HUMAN IL-15
Synonyms
IL-T;RHIL-15;HUMAN IL-T;HUMAN IL-15;IL-15, HUMAN;INTERLEUKIN 15;IL-15 from rat;IL-15 from mouse;HUMAN INTERLEUKIN-15;INTERLEUKIN-15, HUMAN
CBNumber
CB9188037
Formula Weight
0
MOL File
Mol file
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HUMAN IL-15 Property

storage temp. 
−20°C
form 
lyophilized powder
color 
white to off-white
biological source
mouse
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP3077
Product name
IL-15 human
Purity
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging
10μG
Price
$439
Updated
2025/07/31
Sigma-Aldrich
Product number
I8648
Product name
Interleukin-15 human
Purity
>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging
5μg
Price
$332
Updated
2025/07/31
Sigma-Aldrich
Product number
SRP4172
Product name
IL-15 from rat
Purity
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Packaging
10μg
Price
$339
Updated
2023/01/07
Sigma-Aldrich
Product number
SRP4171
Product name
IL-15 from mouse
Purity
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Packaging
10μG
Price
$316
Updated
2022/05/15
Usbiological
Product number
I8437-02
Product name
Interleukin 15
Packaging
500ug
Price
$340
Updated
2021/12/16
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HUMAN IL-15 Chemical Properties,Usage,Production

Biological Activity

Interleukin-15 (IL-15) stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. It exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. On binding to its receptor, IL-15 is indirectly involved in activating proto-oncogenes. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and diseases affiliated with retroviruses like human immunodeficiency virus (HIV) and human T-lymphotropic virus-1 (HTLV-I).

Description

Interleukin-15 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12.9kDa.

The IL-15 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

HUMAN IL-15 Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMAN IL-15Related Search:


  • RECOMBINANT HUMAN IL-15
  • HUMAN IL-15
  • HUMAN IL-T
  • HUMAN INTERLEUKIN-15
  • IL-15, HUMAN
  • INTERLEUKIN 15
  • INTERLEUKIN-15, HUMAN
  • INTERLEUKIN-15 HUMAN, RECOMBINANT
  • INTERLEUKIN-15, HUMAN, RECOMBINANT, E COLI
  • INTERLEUKIN-15 (IL-15)
  • RHIL-15
  • IL-15 from rat
  • IL-15 from mouse
  • IL-T
  • Mouse Interleukin 15 elisa kit