methyl 3-bromopyrazine-2-carboxylate

Product Name: methyl 3-bromopyrazine-2-carboxylate
CAS No.: 51171-02-9
Chemical Name: methyl 3-bromopyrazine-2-carboxylate
Synonyms: 3-BroMo-pyrazine-2-carboxylic acid Methyl ester;Methyl 3-BroMo-2-pyrazinecarboxylate;Methyl 3-bromopyrazine-2-carbo;Methyl 2-bromopyrazine-3-carboxylate;methyl 3-bromopyrazine-2-carboxylate;Methyl 3-bromopyrazine-2-carboxylate 96%;3-bromo-2-Pyrazinecarboxylic acid methyl ester;2-Bromopyrazine-3-carboxylic acid methyl ester;Pyrazinecarboxylic acid, 3-bromo-, methyl ester;2-Pyrazinecarboxylic acid, 3-bromo-, methyl ester
CBNumber: CB92123933
Molecular Formula: C6H5BrN2O2
Formula Weight: 217.02
MOL File: 51171-02-9.mol

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methyl 3-bromopyrazine-2-carboxylate Property

Melting point:: 44℃
Boiling point:: 264.7±35.0℃ (760 Torr)
Density: 1.669±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:: 113.9±25.9℃
storage temp.: 2-8°C
form: solid
pka: -2.41±0.10(Predicted)
color: Off-white to grey
InChI: InChI=1S/C6H5BrN2O2/c1-11-6(10)4-5(7)9-3-2-8-4/h2-3H,1H3
InChIKey: CMITUAXQMWSHLL-UHFFFAOYSA-N
SMILES: C1(C(OC)=O)=NC=CN=C1Br

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M296045
Product name: Methyl3-bromopyrazine-2-carboxylate
Packaging: 1g
Price: $75
Updated: 2021/12/16

Usbiological

Product number: 283166
Product name: Methyl 3-bromopyrazine-2-carboxylate
Packaging: 100mg
Price: $353
Updated: 2021/12/16

TRC

Product number: M296045
Product name: Methyl3-bromopyrazine-2-carboxylate
Packaging: 250mg
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: J97938
Product name: Methyl3-bromopyrazine-2-carboxylate
Packaging: 1g
Price: $60
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0105849
Product name: METHYL 3-BROMOPYRAZINE-2-CARBOXYLATE
Purity: 95.00%
Packaging: 250MG
Price: $831.6
Updated: 2021/12/16

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methyl 3-bromopyrazine-2-carboxylate Chemical Properties,Usage,Production

Synthesis

16298-03-6

51171-02-9

General procedure for the synthesis of methyl methyl 3-bromopyrazine-2-carboxylate from methyl 3-aminopyrazine-2-carboxylate: bromine (3.91 g, 24.46 mmol) was added slowly and dropwise at 0 °C to a stirred mixture containing methyl 3-aminopyrazine-2-carboxylate (1.27 g, 8.29 mmol) and hydrobromic acid (4.70 mL, 41.5 mmol). . Subsequently, a solution of sodium nitrite (1.44 g, 20.9 mmol) dissolved in water (6 mL) was added dropwise. The reaction mixture was continued to be stirred at 0 °C for 15 min. Upon completion of the reaction, the pH was adjusted to 8 with saturated aqueous sodium bicarbonate solution, followed by extraction with ethyl acetate (80 mL) and chloroform (50 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to afford 1.13 g (63% yield) of an orange oil, which solidified to the target product, methyl methyl-3-bromopyrazine-2-carboxylate, upon standing.

References

[1] Patent: WO2006/91506, 2006, A2. Location in patent: Page/Page column 47
[2] Patent: WO2006/49681, 2006, A2. Location in patent: Page/Page column 45-46
[3] Patent: WO2006/121588, 2006, A2. Location in patent: Page/Page column 51
[4] Patent: WO2006/121860, 2006, A2. Location in patent: Page/Page column 51
[5] Patent: WO2006/121904, 2006, A1. Location in patent: Page/Page column 51

methyl 3-bromopyrazine-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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methyl 3-bromopyrazine-2-carboxylate Suppliers

China 90 India 1 Switzerland 1 United Kingdom 3 United States 10 Global 105

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View Lastest Price from methyl 3-bromopyrazine-2-carboxylate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 3-bromopyrazine-2-carboxylate 51171-02-9
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

Career Henan Chemical Co

Product: methyl 3-bromopyrazine-2-carboxylate 51171-02-9
Price: US $1.00/g
Min. Order: 100g
Purity: 99%
Supply Ability: KG/G
Release date: 2019-12-18

51171-02-9, methyl 3-bromopyrazine-2-carboxylateRelated Search:

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methyl 3-bromopyrazine-2-carboxylate

3-BroMo-pyrazine-2-carboxylic acid Methyl ester

Methyl 2-bromopyrazine-3-carboxylate

Methyl 3-BroMo-2-pyrazinecarboxylate

3-bromo-2-Pyrazinecarboxylic acid methyl ester

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2-Bromopyrazine-3-carboxylic acid methyl ester

2-Pyrazinecarboxylic acid, 3-bromo-, methyl ester

methyl 3-bromopyrazine-2-carboxylate ISO 9001：2015 REACH

51171-02-9

alkyl bromide| carboxylic ester