NF 023
- Product Name
- NF 023
- CAS No.
- 104869-31-0
- Chemical Name
- NF 023
- Synonyms
- NF 023;NF023 hexasodium;NF 023 hydrate;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT;8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate;8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
- CBNumber
- CB9220784
- Molecular Formula
- C33H20N4Na6O19S6
- Formula Weight
- 1106.86
- MOL File
- 104869-31-0.mol
NF 023 Property
- storage temp.
- Desiccate at RT
- solubility
- H2O: >20 mg/mL
- form
- crystalline
- color
- white
- Water Solubility
- Soluble to 100 mM in water
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N8652
- Product name
- NF 023 hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 10mg
- Price
- $112.2
- Updated
- 2024/03/01
- Product number
- N8652
- Product name
- NF 023 hydrate
- Purity
- ≥98% (HPLC), solid
- Packaging
- 50mg
- Price
- $602
- Updated
- 2024/03/01
- Product number
- 480415
- Product name
- NF023
- Purity
- A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go/Gi group (EC?? ~ 300 nM).
- Packaging
- 10MG
- Price
- $332
- Updated
- 2024/03/01
- Product number
- 1240
- Product name
- NF023
- Packaging
- 10
- Price
- $182
- Updated
- 2021/12/16
- Product number
- 1240
- Product name
- NF023
- Packaging
- 50
- Price
- $767
- Updated
- 2021/12/16
NF 023 Chemical Properties,Usage,Production
Uses
NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist.
Biological Activity
A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~? 300 nM).
Biochem/physiol Actions
NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.
storage
Desiccate at RT
NF 023 Preparation Products And Raw materials
Raw materials
Preparation Products
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