ChemicalBook > CAS DataBase List > NF 023

NF 023

Product Name
NF 023
CAS No.
104869-31-0
Chemical Name
NF 023
Synonyms
NF 023;NF023 hexasodium;NF 023 hydrate;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT;8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate;8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
CBNumber
CB9220784
Molecular Formula
C33H20N4Na6O19S6
Formula Weight
1106.86
MOL File
104869-31-0.mol
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NF 023 Property

storage temp. 
Desiccate at RT
solubility 
H2O: >20 mg/mL
form 
crystalline
color 
white
Water Solubility 
Soluble to 100 mM in water
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N8652
Product name
NF 023 hydrate
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$112.2
Updated
2024/03/01
Sigma-Aldrich
Product number
N8652
Product name
NF 023 hydrate
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$602
Updated
2024/03/01
Sigma-Aldrich
Product number
480415
Product name
NF023
Purity
A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go/Gi group (EC?? ~ 300 nM).
Packaging
10MG
Price
$332
Updated
2024/03/01
Tocris
Product number
1240
Product name
NF023
Packaging
10
Price
$182
Updated
2021/12/16
Tocris
Product number
1240
Product name
NF023
Packaging
50
Price
$767
Updated
2021/12/16
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NF 023 Chemical Properties,Usage,Production

Uses

NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist.

Biological Activity

A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~? 300 nM).

Biochem/physiol Actions

NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.

storage

Desiccate at RT

NF 023 Preparation Products And Raw materials

Raw materials

Preparation Products

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NF 023 Suppliers

China 34 Germany 2 Switzerland 1 United Kingdom 3 United States 8 Global 48
3B Pharmachem (Wuhan) International Co.,Ltd.
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104869-31-0, NF 023Related Search:

1,5-NAPHTHALENEDISULFONIC ACID DISODIUM SALT, DIHYDRATE, 98 1-Naphthylamine-4,6,8-trisulfonic acid Disodium 1,5-naphthalenedisulfonate 8-AMINO-1,5-NAPHTHALENEDISULFONIC ACID MONOSODIUM SALT NF 023 sodium N-benzylsulphanilate Naphthalene-1,3,5-trisulphonic acid

  • NF 023
  • 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA
  • 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT
  • 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT
  • 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
  • 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt
  • 8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
  • NF 023 hydrate
  • 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt
  • NF023 hexasodium
  • 104869-31-0
  • C35H20N4Na6O21S6
  • C35H20N4O21S66Na
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Ion Channels
  • Ligand-Gated Ion Channels
  • P2X Receptor Modulators
  • Purinergics P2 receptor