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N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE

Product Name
N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE
CAS No.
56619-93-3
Chemical Name
N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE
Synonyms
SKL910;dimethylpropanamide;N-(3-methoxyphenyl)pivalamide;N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE;N-(3-Methoxy-phenyl)-2,2-dimethyl-propiomide;N-(3-Methoxyphenyl)-2,2-dimethylpropionamide;N1-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE;N-(2,2-Dimethylpropanoyl)-3-(methoxy)aniline;PropanaMide, N-(3-Methoxyphenyl)-2,2-diMethyl-;Propanamide,N-(3-methoxy phenyl)-2,2-dimethyl-(9CI)
CBNumber
CB9228962
Molecular Formula
C12H17NO2
Formula Weight
207.27
MOL File
56619-93-3.mol
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N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE Property

Melting point:
125-126°C
Boiling point:
358.2±25.0 °C(Predicted)
Density 
1.057±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
14.66±0.70(Predicted)
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Safety

HazardClass 
IRRITANT
HS Code 
2922290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B488903
Product name
N-(3-methoxyphenyl)-2,2-dimethylpropanamide
Packaging
100mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
044907
Product name
N-(3-Methoxyphenyl)-2,2-dimethylpropanamide
Purity
>95%
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
044907
Product name
N-(3-Methoxyphenyl)-2,2-dimethylpropanamide
Purity
>95%
Packaging
1g
Price
$100
Updated
2021/12/16
Apolloscientific
Product number
OR22046
Product name
N-(2,2-Dimethylpropanoyl)-3-(methoxy)aniline
Purity
97%
Packaging
5g
Price
$116
Updated
2021/12/16
ChemScene
Product number
CS-0035852
Product name
N-(3-Methoxyphenyl)pivalamide
Packaging
5g
Price
$157
Updated
2021/12/16
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N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE Chemical Properties,Usage,Production

Synthesis

3282-30-2

536-90-3

56619-93-3

Pivaloyl chloride (25.0 mL, 205 mmol) was slowly added dropwise at 0 °C under argon protection to a mixed solution of ethyl acetate (300 mL) and purified water (860 mL) containing m-aminoanisole (21.9 mL, 195 mmol), sodium carbonate monohydrate (62.0 g, 500 mmol). The reaction mixture was stirred at 0 °C for 1 h. The organic layer was separated and the aqueous layer was extracted with ethyl acetate (300 mL). The organic layers were combined, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure and the residue was recrystallized with ethyl acetate to afford N-(3-methoxyphenyl)pivalamide (Compound 1a) (40.2 g, 194 mmol, 99.5% yield) as a colorless solid.TLC showed Rf = 0.50 (hexane/ethyl acetate = 6:1).

References

[1] Journal of the American Chemical Society, 2004, vol. 126, # 4, p. 1150 - 1160
[2] Patent: EP2881397, 2015, A1. Location in patent: Paragraph 0053; 0054; 0055
[3] Patent: US2016/303089, 2016, A1. Location in patent: Paragraph 0161; 0162; 0163; 0164
[4] Patent: WO2004/103996, 2004, A1. Location in patent: Page 51
[5] Synlett, 2011, # 7, p. 1018 - 1022

N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE manufacturers

Career Henan Chemical Co
Product
N-(3-METHOXYPHENYL)-2,2-DIMETHYLPROPANAMIDE 56619-93-3
Price
US $3.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2019-07-10