ChemicalBook > CAS DataBase List > Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate

Product Name
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
CAS No.
117337-19-6
Chemical Name
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
Synonyms
kih-9201;Hsdb 7270;FLUTHIACET-METHYL;Eluthiacet-methyl;Semaglutide Impurity 9;Fluthiacet-methyl [iso];Fluthiacet-methyl Standard;Fluthiacet-methyl Solution;1000 μg/mL in Acetonitrile;C13862000 Fluthiacet-methyl
CBNumber
CB9232165
Molecular Formula
C15H15ClFN3O3S2
Formula Weight
403.88
MOL File
117337-19-6.mol
More
Less

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Property

Melting point:
104.6°
Boiling point:
503.5±60.0 °C(Predicted)
Density 
1.57±0.1 g/cm3(Predicted)
storage temp. 
0-6°C
pka
-2.86±0.20(Predicted)
BRN 
11510131
EPA Substance Registry System
Fluthiacet-methyl (117337-19-6)
More
Less

Safety

Hazard Codes 
Xi,N
Risk Statements 
36-50
Safety Statements 
26-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
HS Code 
29309090
Hazardous Substances Data
117337-19-6(Hazardous Substances Data)
Toxicity
LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Miyazawa)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32464
Product name
Fluthiacet-methyl
Purity
PESTANAL
Packaging
25mg
Price
$80.9
Updated
2022/05/15
TRC
Product number
F599440
Product name
Fluthiacet-​methyl
Packaging
5mg
Price
$330
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AGR0000191
Product name
FLUTHIACET-METHYL
Purity
98.00%
Packaging
0.5G
Price
$1276
Updated
2021/12/16
AHH
Product number
MT-51867
Product name
Fluthiacet-methyl
Purity
98%
Packaging
0.5g
Price
$590
Updated
2021/12/16
More
Less

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Chemical Properties,Usage,Production

Uses

Herbicide.

Definition

ChEBI: Fluthiacet-methyl is a methyl ester resulting from the formal condensation of the carboxy group of fluthiacet with methanol. A proherbicide for fluthiacet, it is used for the control of broad-leaved weeds in crops such as maize and soya. It has a role as an agrochemical, an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor and a proherbicide. It is an organic sulfide, a methyl ester, a member of monochlorobenzenes, a member of monofluorobenzenes and a thiadiazolopyridazine. It is functionally related to a fluthiacet.

Metabolic pathway

Fluthiacet methyl is converted to its isomer, urazole, by glutathione S-transferase (GST) and glutathione (GSH) from some plants and rat liver microsomes. Fluthiacet methyl inhibits Protox (protoporphyrinogen oxidase) activity after conversion to the corresponding urazole by GST and GSH. Fluthiacet methyl is chemically converted to urazole with a thiol anion in media by the nucleophilic reaction. It is also suggested that a free acid of urazole, desulfated urazole, and the oxidative ring-cleaved formyl degradation products result from hydrolysis with esterase from soybean seedlings.
When fluthiacet methyl is administered orally to rats in a single dose, 63-85% of the dose is excreted in the feces and 10-23% in the urine, respectively, after 48 h. The main metabolite is the isomer of fluthiacet methyl (urazole) which is also identified in the soil degradation products. Monohydroxylated products on the pyridazine ring are identified as metabolites by rats only.

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Suppliers

China 32 Germany 1 India 1 Japan 2 United Kingdom 3 United States 8 Global 47
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD.
Tel
86-029-85456576
Fax
86-029-85456576-808
Email
daisy_wang@vip.163.com
Country
China
ProdList
292
Advantage
55
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10009
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
ShangHai Anpel Co, Ltd.
Tel
18501792038; 18501792038
Email
shanpel@anpel.com.cn
Country
China
ProdList
9611
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Aobolihui
Tel
0917-18691729 18691729963
Email
2553382659@qq.com
Country
China
ProdList
4747
Advantage
58
Shanghai Bikai Technology Co. , Ltd.
Tel
18516304666
Email
christina.feng@cpachem-sh.com
Country
China
ProdList
3100
Advantage
58
Nantong Zhonghe Chemical New Materials Co., Ltd
Tel
13003551299 13003551299
Email
2369399482@qq.com
Country
China
ProdList
7566
Advantage
58
guoyungurui
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
10335
Advantage
58
CHANG ZHOU A SANG QI TECHNOLOGY CO.,LTD
Tel
18961267976
Email
1184262569@qq.com
Country
China
ProdList
498
Advantage
58
Shaanxi Xihua Chemical Industry Co., Ltd
Tel
17691182729 13992773979
Email
1049@dideu.com
Country
China
ProdList
7875
Advantage
58
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
71677
Advantage
58
Tel
58896805
Email
7993601name@qq.com
Country
CHINA
ProdList
15340
Advantage
58
Hangzhou FandaChem Co.,Ltd.
Tel
+8615858145714
Fax
+86-571-56059825
Email
FandaChem@Gmail.com
Country
China
ProdList
9206
Advantage
55
SUZHOU SENFEIDA CHEMICAL CO.,LTD
Tel
+86-0512-83500002 +8615195660023
Email
sales@senfeida.com
Country
China
ProdList
23046
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49978
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58
Richchem International Trading Co., Ltd
Tel
--
Fax
--
Email
sinochemx@online.ln.cn
Country
China
ProdList
738
Advantage
69
Zhejiang Rayfull Holding Co., Ltd
Tel
--
Fax
--
Email
info@rayfull.com
Country
China
ProdList
245
Advantage
47
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd
Tel
--
Fax
--
Email
sales@yickvic.com
Country
China
ProdList
6206
Advantage
58
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67

117337-19-6, Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetateRelated Search:

Oxalic acid dihydrate IMINOCTADINE TRIS(ALBESILATE) Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate 2-CHLORO-4-FLUOROTHIOPHENOL o-chlorophenylthioacetate (4-FLUOROPHENYLTHIO)ACETIC ACID 2-(2-CHLORO-4-FLUOROPHENYLTHIO)ACETIC ACID

  • FLUTHIACET-METHYL
  • Methyl {2-chloro-4-fluoro-5-[(EZ)-5,6,7,8-tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylideneamino]phenylthio}acetate
  • Fluthiacet-methyl Standard
  • Fluthiacet-methyl Solution, 1000ppm
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-yliden
  • Acetic acid, ((2-chloro-4-fluoro-5-((tetrahydro-3-oxo-1H,3H-(1,3,4)thiadiazolo(3,4-A)pyridazin-1-ylidene)amino)phenyl)thio)-, methyl ester
  • Fluthiacet-methyl [iso]
  • Hsdb 7270
  • fluthiacet-methyl (bsi, pa iso)
  • kih-9201
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
  • Eluthiacet-methyl
  • [[2-Chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo [3,4-a]pyridazin-1-ylidine)amino]phenyl]thioacetic acid methyl ester
  • Acetic acid, 2-[[2-chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]thio]-, methyl ester
  • Fluthiacet-methyl Solution
  • 1000 μg/mL in Acetonitrile
  • Fluthiacet-methyl Solution in Methanol, 100μg/mL
  • C13862000 Fluthiacet-methyl
  • Fluthiacet-methyl in Acetonitrile
  • Semaglutide Impurity 9
  • 117337-19-6
  • C15H15ClFN3O3S2
  • Cl5H15ClFN3O3S2