ChemicalBook > CAS DataBase List > Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate

Product Name
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
CAS No.
117337-19-6
Chemical Name
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
Synonyms
kih-9201;Hsdb 7270;FLUTHIACET-METHYL;Eluthiacet-methyl;Semaglutide Impurity 9;Fluthiacet-methyl [iso];Fluthiacet-methyl Standard;Fluthiacet-methyl Solution;1000 μg/mL in Acetonitrile;C13862000 Fluthiacet-methyl
CBNumber
CB9232165
Molecular Formula
C15H15ClFN3O3S2
Formula Weight
403.88
MOL File
117337-19-6.mol
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Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Property

Melting point:
104.6°
Boiling point:
503.5±60.0 °C(Predicted)
Density 
1.57±0.1 g/cm3(Predicted)
storage temp. 
0-6°C
pka
-2.86±0.20(Predicted)
BRN 
11510131
EPA Substance Registry System
Fluthiacet-methyl (117337-19-6)
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Safety

Hazard Codes 
Xi,N
Risk Statements 
36-50
Safety Statements 
26-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
HS Code 
29309090
Hazardous Substances Data
117337-19-6(Hazardous Substances Data)
Toxicity
LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Miyazawa)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32464
Product name
Fluthiacet-methyl
Purity
PESTANAL
Packaging
25mg
Price
$80.9
Updated
2022/05/15
TRC
Product number
F599440
Product name
Fluthiacet-​methyl
Packaging
5mg
Price
$330
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AGR0000191
Product name
FLUTHIACET-METHYL
Purity
98.00%
Packaging
0.5G
Price
$1276
Updated
2021/12/16
AHH
Product number
MT-51867
Product name
Fluthiacet-methyl
Purity
98%
Packaging
0.5g
Price
$590
Updated
2021/12/16
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Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Chemical Properties,Usage,Production

Uses

Herbicide.

Definition

ChEBI: Fluthiacet-methyl is a methyl ester resulting from the formal condensation of the carboxy group of fluthiacet with methanol. A proherbicide for fluthiacet, it is used for the control of broad-leaved weeds in crops such as maize and soya. It has a role as an agrochemical, an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor and a proherbicide. It is an organic sulfide, a methyl ester, a member of monochlorobenzenes, a member of monofluorobenzenes and a thiadiazolopyridazine. It is functionally related to a fluthiacet.

Metabolic pathway

Fluthiacet methyl is converted to its isomer, urazole, by glutathione S-transferase (GST) and glutathione (GSH) from some plants and rat liver microsomes. Fluthiacet methyl inhibits Protox (protoporphyrinogen oxidase) activity after conversion to the corresponding urazole by GST and GSH. Fluthiacet methyl is chemically converted to urazole with a thiol anion in media by the nucleophilic reaction. It is also suggested that a free acid of urazole, desulfated urazole, and the oxidative ring-cleaved formyl degradation products result from hydrolysis with esterase from soybean seedlings.
When fluthiacet methyl is administered orally to rats in a single dose, 63-85% of the dose is excreted in the feces and 10-23% in the urine, respectively, after 48 h. The main metabolite is the isomer of fluthiacet methyl (urazole) which is also identified in the soil degradation products. Monohydroxylated products on the pyridazine ring are identified as metabolites by rats only.

Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Suppliers

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117337-19-6, Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetateRelated Search:

Oxalic acid dihydrate IMINOCTADINE TRIS(ALBESILATE) Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate 2-CHLORO-4-FLUOROTHIOPHENOL o-chlorophenylthioacetate (4-FLUOROPHENYLTHIO)ACETIC ACID 2-(2-CHLORO-4-FLUOROPHENYLTHIO)ACETIC ACID

  • FLUTHIACET-METHYL
  • Methyl {2-chloro-4-fluoro-5-[(EZ)-5,6,7,8-tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylideneamino]phenylthio}acetate
  • Fluthiacet-methyl Standard
  • Fluthiacet-methyl Solution, 1000ppm
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-yliden
  • Acetic acid, ((2-chloro-4-fluoro-5-((tetrahydro-3-oxo-1H,3H-(1,3,4)thiadiazolo(3,4-A)pyridazin-1-ylidene)amino)phenyl)thio)-, methyl ester
  • Fluthiacet-methyl [iso]
  • Hsdb 7270
  • fluthiacet-methyl (bsi, pa iso)
  • kih-9201
  • Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
  • Eluthiacet-methyl
  • [[2-Chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo [3,4-a]pyridazin-1-ylidine)amino]phenyl]thioacetic acid methyl ester
  • Acetic acid, 2-[[2-chloro-4-fluoro-5-[(tetrahydro-3-oxo-1H,3H-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]thio]-, methyl ester
  • Fluthiacet-methyl Solution
  • 1000 μg/mL in Acetonitrile
  • Fluthiacet-methyl Solution in Methanol, 100μg/mL
  • C13862000 Fluthiacet-methyl
  • Fluthiacet-methyl in Acetonitrile
  • Semaglutide Impurity 9
  • 117337-19-6
  • C15H15ClFN3O3S2
  • Cl5H15ClFN3O3S2