ChemicalBook > CAS DataBase List > 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE

2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE

Product Name: 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
CAS No.: 70298-88-3
Chemical Name: 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
Synonyms: Zinc04352664;N-(3-Pyridyl)pivalaMide;3-(Pivaloylamino)pyridine;N-(Pyridin-3-yl)pivalamide;N-(3-Pyridyl)pivalamide>N-(3-Pyridyl)pivalamide, 95%;2,2-diMethyl-N-pyridin-3-ylpropanaMide;2,2-Dimethyl-N-3-pyridinyl-propanamide;2,2-Dimethyl-N-(3-pyridyl)propionamide;Propanamide, 2,2-dimethyl-N-3-pyridinyl-
CBNumber: CB9233076
Molecular Formula: C10H14N2O
Formula Weight: 178.23
MOL File: 70298-88-3.mol

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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Property

Melting point:: 129-131℃
Boiling point:: 337.5±15.0 °C(Predicted)
Density: 1.078±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 14.19±0.70(Predicted)
color: White to Light yellow to Light orange

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE001300
Product name: 2,2-Dimethyl-N-pyridin-3-yl-propionamide
Purity: Aldrich
Packaging: 1g
Price: $167
Updated: 2023/01/07

TCI Chemical

Product number: P2109
Product name: N-(3-Pyridyl)pivalamide
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $51
Updated: 2025/07/31

TCI Chemical

Product number: P2109
Product name: N-(3-Pyridyl)pivalamide
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $150
Updated: 2025/07/31

Apolloscientific

Product number: OR909970
Product name: N-(Pyridin-3-yl)pivalamide
Purity: 98%
Packaging: 100g
Price: $425
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0019237
Product name: 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
Purity: 95.00%
Packaging: 1G
Price: $652.58
Updated: 2021/12/16

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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Chemical Properties,Usage,Production

Synthesis

462-08-8

3282-30-2

70298-88-3

In a dry three-necked flask, 3-aminopyridine (20.0 g, 212.5 mmol), 4-dimethylaminopyridine (DMAP) (0.3 g, 2.1 mmol) and pyridine (33.6 g, 425.0 mmol) were dissolved in anhydrous dichloromethane (200 mL). Valeroyl chloride (28.2 g, 233.7 mmol) was added slowly and dropwise under cooling in an ice bath. The reaction mixture was kept stirred at 0 °C for 2 hours. After completion of the reaction, the reaction solution was slowly poured into ice water and the reaction was quenched with 1N hydrochloric acid solution. Subsequently, the mixture was extracted with dichloromethane (250 mL × 3), the organic phases were combined and washed with saturated saline (200 mL × 1). Finally, the solvent was removed by distillation under reduced pressure to afford 3-pivalamido pyridine (36.2 g) as a white solid in 95.5% yield.

References

[1] Synthesis, 1982, # 6, p. 499 - 500
[2] Tetrahedron, 2009, vol. 65, # 18, p. 3668 - 3672
[3] Patent: CN107382839, 2017, A. Location in patent: Paragraph 0005; 0012-0013; 0020-0021; 0028-0029; 0036-0037
[4] Patent: WO2014/198844, 2014, A1. Location in patent: Page/Page column 15; 16
[5] Patent: WO2014/198848, 2014, A2. Location in patent: Page/Page column 14; 15

2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Suppliers

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View Lastest Price from 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE manufacturers

Career Henan Chemical Co

Product: 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE 70298-88-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-20

70298-88-3, 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDERelated Search:

N-(4-FORMYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 1-(2-CHLOROPYRIDIN-3-YL)-3,3-DIMETHYLAZETIDIN-2-ONE N-(4-IODO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-2-YL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE N-(4-[1,3]DIOXOLAN-2-YL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 3-CHLORO-N-(2-CHLORO-3-PYRIDINYL)-2,2-DIMETHYLPROPANAMIDE N-(4-HYDROXYMETHYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(5-BROMO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(4-HYDROXY-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(4-TERT-BUTYLSULFANYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 3-(2,2-DIMETHYL-PROPIONYLAMINO)-ISONICOTINIC ACID 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE N1-[6-(2,4-DIFLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE N1-[6-(2-FLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE 2-CYANO-3-N-PIVALOYL-AMINOPYRIDINE N1-[6-(4-FLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE N1-[2-(2,4-DIFLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE

2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE

N-(Pyridin-3-yl)pivalamide

2,2-Dimethyl-N-pyridine-3yl-propionamide

3-(Pivaloylamino)pyridine

2,2-Dimehtyl-N-pyridin-3-yl-propionamide

Zinc04352664

2,2-DiMethyl-N-(3-pyridyl)propionaMide, 98%

N-(3-Pyridyl)pivalaMide

2,2-diMethyl-N-pyridin-3-ylpropanaMide

N-(3-Pyridyl)pivalamide&gt

Propanamide, 2,2-dimethyl-N-3-pyridinyl-

2,2-Dimethyl-N-3-pyridinyl-propanamide

N-(3-Pyridyl)pivalamide, 95%

2,2-dimethyl-N-(pyridin-3-yl)propanamide - [D87280]

2,2-Dimethyl-N-(3-pyridyl)propionamide

70298-88-3

Amines

blocks

Pyridines