ChemicalBook > CAS DataBase List > 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE

2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE

Product Name
2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
CAS No.
70298-88-3
Chemical Name
2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
Synonyms
Zinc04352664;N-(3-Pyridyl)pivalaMide;3-(Pivaloylamino)pyridine;N-(Pyridin-3-yl)pivalamide;N-(3-Pyridyl)pivalamide>N-(3-Pyridyl)pivalamide, 95%;2,2-diMethyl-N-pyridin-3-ylpropanaMide;2,2-Dimethyl-N-3-pyridinyl-propanamide;2,2-Dimethyl-N-(3-pyridyl)propionamide;Propanamide, 2,2-dimethyl-N-3-pyridinyl-
CBNumber
CB9233076
Molecular Formula
C10H14N2O
Formula Weight
178.23
MOL File
70298-88-3.mol
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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Property

Melting point:
129-131℃
Boiling point:
337.5±15.0 °C(Predicted)
Density 
1.078±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
14.19±0.70(Predicted)
color 
White to Light yellow to Light orange
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE001300
Product name
2,2-Dimethyl-N-pyridin-3-yl-propionamide
Purity
Aldrich
Packaging
1g
Price
$167
Updated
2023/01/07
TCI Chemical
Product number
P2109
Product name
N-(3-Pyridyl)pivalamide
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$51
Updated
2025/07/31
TCI Chemical
Product number
P2109
Product name
N-(3-Pyridyl)pivalamide
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$150
Updated
2025/07/31
Apolloscientific
Product number
OR909970
Product name
N-(Pyridin-3-yl)pivalamide
Purity
98%
Packaging
100g
Price
$425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019237
Product name
2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
Purity
95.00%
Packaging
1G
Price
$652.58
Updated
2021/12/16
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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Chemical Properties,Usage,Production

Synthesis

462-08-8

3282-30-2

70298-88-3

In a dry three-necked flask, 3-aminopyridine (20.0 g, 212.5 mmol), 4-dimethylaminopyridine (DMAP) (0.3 g, 2.1 mmol) and pyridine (33.6 g, 425.0 mmol) were dissolved in anhydrous dichloromethane (200 mL). Valeroyl chloride (28.2 g, 233.7 mmol) was added slowly and dropwise under cooling in an ice bath. The reaction mixture was kept stirred at 0 °C for 2 hours. After completion of the reaction, the reaction solution was slowly poured into ice water and the reaction was quenched with 1N hydrochloric acid solution. Subsequently, the mixture was extracted with dichloromethane (250 mL × 3), the organic phases were combined and washed with saturated saline (200 mL × 1). Finally, the solvent was removed by distillation under reduced pressure to afford 3-pivalamido pyridine (36.2 g) as a white solid in 95.5% yield.

References

[1] Synthesis, 1982, # 6, p. 499 - 500
[2] Tetrahedron, 2009, vol. 65, # 18, p. 3668 - 3672
[3] Patent: CN107382839, 2017, A. Location in patent: Paragraph 0005; 0012-0013; 0020-0021; 0028-0029; 0036-0037
[4] Patent: WO2014/198844, 2014, A1. Location in patent: Page/Page column 15; 16
[5] Patent: WO2014/198848, 2014, A2. Location in patent: Page/Page column 14; 15

2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE Suppliers

China 86 Germany 2 India 9 Japan 1 The Netherlands 1 United Kingdom 3 United States 22 Global 124
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE manufacturers

Career Henan Chemical Co
Product
2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE 70298-88-3
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-20

70298-88-3, 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDERelated Search:

N-(4-FORMYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 1-(2-CHLOROPYRIDIN-3-YL)-3,3-DIMETHYLAZETIDIN-2-ONE N-(4-IODO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-2-YL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE N-(4-[1,3]DIOXOLAN-2-YL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 3-CHLORO-N-(2-CHLORO-3-PYRIDINYL)-2,2-DIMETHYLPROPANAMIDE N-(4-HYDROXYMETHYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(5-BROMO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(4-HYDROXY-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(4-TERT-BUTYLSULFANYL-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE 3-(2,2-DIMETHYL-PROPIONYLAMINO)-ISONICOTINIC ACID 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE N1-[6-(2,4-DIFLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE N1-[6-(2-FLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE 2-CYANO-3-N-PIVALOYL-AMINOPYRIDINE N1-[6-(4-FLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE N1-[2-(2,4-DIFLUOROPHENOXY)-3-PYRIDYL]-3-CHLORO-2,2-DIMETHYLPROPANAMIDE

  • 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE
  • N-(Pyridin-3-yl)pivalamide
  • 2,2-Dimethyl-N-pyridine-3yl-propionamide
  • 3-(Pivaloylamino)pyridine
  • 2,2-Dimehtyl-N-pyridin-3-yl-propionamide
  • Zinc04352664
  • 2,2-DiMethyl-N-(3-pyridyl)propionaMide, 98%
  • N-(3-Pyridyl)pivalaMide
  • 2,2-diMethyl-N-pyridin-3-ylpropanaMide
  • N-(3-Pyridyl)pivalamide&gt
  • Propanamide, 2,2-dimethyl-N-3-pyridinyl-
  • 2,2-Dimethyl-N-3-pyridinyl-propanamide
  • N-(3-Pyridyl)pivalamide, 95%
  • 2,2-dimethyl-N-(pyridin-3-yl)propanamide - [D87280]
  • 2,2-Dimethyl-N-(3-pyridyl)propionamide
  • 70298-88-3
  • Amines
  • blocks
  • Pyridines