(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione

Product Name: (3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione
CAS No.: 34532-68-8
Chemical Name: (3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione
Synonyms: Arnicolide D;Plenolin methacrylate;(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl methacrylate;2-Methylpropenoic acid [(3S)-2,3,3aα,4,4a,5,7aα,8,9,9aα-decahydro-3β,4aβ,8α-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4α-yl] ester;Mammalian target of Rapamycin,Phosphoinositide 3-kinase,inhibit,Inhibitor,Caspase,mTOR,Arnicolide D,PKB,Akt,PI3K,STAT,Protein kinase B;2-Propenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester
CBNumber: CB92382093
Molecular Formula: C19H24O5
Formula Weight: 332.39
MOL File: 34532-68-8.mol

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(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione Property

storage temp.: 4°C, protect from light
solubility: Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0100262
Product name: ArnicolideD
Purity: 99.20%
Packaging: 1mg
Price: $190
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594580
Product name: Arnicolide D
Packaging: 5mg
Price: $513.4
Updated: 2021/12/16

ChemScene

Product number: CS-0100262
Product name: ArnicolideD
Purity: 99.20%
Packaging: 5mg
Price: $571
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594580
Product name: Arnicolide D
Packaging: 10mg
Price: $715.7
Updated: 2021/12/16

Arctom

Product number: SY232726
Product name: ArnicolideD;Plenolinmethacrylate
Packaging: 5mg
Price: $1030.91
Updated: 2021/12/16

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(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione Chemical Properties,Usage,Production

Uses

food and beverages
pharmaceutical

Definition

ChEBI: Arnicolide D is a sesquiterpene lactone.

in vivo

Arnicolide D (4-8 mg/kg; intraperitoneal injection; 15 days) has anti-melanoma effects in the B16F10 allograft mouse model^[3].

Animal Model:	Male 6-week old C57/BL6 mice treated B16F10^[3]
Dosage:	4 and 8 mg/kg
Administration:	Intraperitoneal injection (i.p.); 15 days
Result:	Reduced the average tumor weight by 53.7% compared with the vehicle-treated group at a dose of 4 mg/kg. Did not cause death, toxic symptoms in mice, and no abnormalities were found during autopsy. Was more effective at 4 mg/kg than at 8 mg/kg in suppressing tumor growth.

(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione Suppliers

China 71 United States 6 Global 77

Nanjing Chemlin Chemical Co., Ltd

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BOC Sciences

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Yihe Biological Technology Co., Ltd.

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34532-68-8, (3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dioneRelated Search:

8,9-epoxyl-3-isobutyryloxy-10-(2-methylbutanoyl)thymol 1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester medicagenic acid Brassinolide Acitretin (2alpha,3beta,19alpha)-2,3,19-Trihydroxyolean-12-en-28-oic acid beta-D-glucopyranosyl ester Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside 8-epidiosbulbin E acetate TRIBULOSIDE 10-isobutyryloxy-8,9-epoxythymol isobutyrate

(3aR)-4,4a,7aα,8,9,9aα-Hexahydro-4α-(methacryloyloxy)-3β,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5(3H,3aαH)-dione

2-Methylpropenoic acid [(3S)-2,3,3aα,4,4a,5,7aα,8,9,9aα-decahydro-3β,4aβ,8α-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4α-yl] ester

Plenolin methacrylate

Arnicolide D

2-Propenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester

Mammalian target of Rapamycin,Phosphoinositide 3-kinase,inhibit,Inhibitor,Caspase,mTOR,Arnicolide D,PKB,Akt,PI3K,STAT,Protein kinase B

(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl methacrylate

34532-68-8

plant extracts

standard material,plant extracts