PLEVITREXED

Product Name: PLEVITREXED
CAS No.: 153538-08-0
Chemical Name: PLEVITREXED
Synonyms: (Rac)-BGC9331;(Rac)-ZD 9331;(Rac)-Plevitrexed;(Rac)Plevitrexed,(Rac) Plevitrexed;2H-Tetrazole-5-butanoic acid, α-[[4-[[(3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-2-fluorobenzoyl]amino]-
CBNumber: CB92451263
Molecular Formula: C26H25FN8O4
Formula Weight: 532.53
MOL File: 153538-08-0.mol

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PLEVITREXED Property

Density: 1.44±0.1 g/cm3(Predicted)
pka: 3.35±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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PLEVITREXED Chemical Properties,Usage,Production

Uses

(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)?is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem.?2013?Jul 11;56(13):5446-55. DOI:10.1021/jm400490e

PLEVITREXED Preparation Products And Raw materials

Raw materials

Preparation Products

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PLEVITREXED Suppliers

China 5 United States 3 Global 8

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
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Guangzhou Baide Biotechnology Co., Ltd.

Tel: 18925065404
Country: CHINA
ProdList: 168
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153538-08-0, PLEVITREXEDRelated Search:

7-METHYLQUINAZOLIN-4(1H)-ONE PROP-2-YNYL-P-TOLYL-AMINE 4-amino-2-fluoro-N-methylbenzamide PLEVITREXED

(Rac)-BGC9331

(Rac)-Plevitrexed

(Rac)-ZD 9331

2H-Tetrazole-5-butanoic acid, α-[[4-[[(3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-2-fluorobenzoyl]amino]-

(Rac)Plevitrexed,(Rac) Plevitrexed

153538-08-0