4-amino-2-fluoro-N-methylbenzamide

Product Name: 4-amino-2-fluoro-N-methylbenzamide
CAS No.: 915087-25-1
Chemical Name: 4-amino-2-fluoro-N-methylbenzamide
Synonyms: N-Methyl-2-fluoro-4-aminobenzamide;N-Methyl-4-amino-2-fluoro-benzamide;Enzalutamide ITS-3;Enzalutamide Impurity 40;Enzalutamide Impurity 20;4-AMINO-2-FLUORO-N-METHYLBENZAMIDE;4-amino-2-fluoro-N-menthylbenzamide;N-Methyl-2-fluoro-4-AminobenzoylAmine;2. 4-aMino-2-fluoro-N-MethylbenzaMide;BenzaMide, 4-aMino-2-fluoro-N-Methyl-
CBNumber: CB02452656
Molecular Formula: C8H9FN2O
Formula Weight: 168.17
MOL File: 915087-25-1.mol

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4-amino-2-fluoro-N-methylbenzamide Property

Melting point:: 160 - 163°C
Boiling point:: 320℃
Density: 1.234
Flash point:: 147℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.12±0.46(Predicted)
color: White to Off-White
Stability:: Moisture Sensitive
InChI: InChI=1S/C8H9FN2O/c1-11-8(12)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3,(H,11,12)
InChIKey: XOKAXPQJUODMSH-UHFFFAOYSA-N
SMILES: C(NC)(=O)C1=CC=C(N)C=C1F

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Safety

HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Signal word: Warning

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N-Bromosuccinimide Price

TRC

Product number: A609743
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 25g
Price: $275
Updated: 2021/12/16

TRC

Product number: A609743
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 50g
Price: $520
Updated: 2021/12/16

AK Scientific

Product number: J95296
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 5g
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: 3273AH
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 25g
Price: $231
Updated: 2021/12/16

Apolloscientific

Product number: PC905580
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Purity: 98%
Packaging: 10g
Price: $235
Updated: 2021/12/16

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4-amino-2-fluoro-N-methylbenzamide Chemical Properties,Usage,Production

Uses

4-amino-2-fluoro-N-methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors.

Description

4-amino-2-fluoro-N-methylbenzamide is a novel antiandrogen drug MDV (Marek's Disease Virus) 3100 key intermediate which is the new generation oral androgen antagonist medicine of united states drug developer Medivation company exploitation, be mainly used in treating advanced prostate cancer (CRPC) patient.

Preparation

2-fluoro-4-nitrotoluene as raw material, through potassium permanganate oxidation, the thionyl chloride chlorination, methylamine amination, and Pd/C hydrogenation reduction prepare 4-amino-2-fluoro-N-methylbenzamide.

4-amino-2-fluoro-N-methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-amino-2-fluoro-N-methylbenzamide Suppliers

Canada 1 China 218 India 15 Ukraine 1 United States 6 Global 241

Haohong (Qihe) Medical Technology Co., LTD

Tel: 18068541569 18660163165
Fax: 0519-85551569
Email: sale@inyelchem.com
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Beijing Sai Siyuan Biomedical Technology Co., Ltd.

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Anhui Dexinjia Biopharm Co., Ltd

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Chemvon Biotechnology Co., Ltd

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ChemFuture PharmaTech (Jiangsu) Ltd

Tel: 5108538618
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Email: suger.wang@chemfuture.com
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Energy Chemical

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Jia Xing Isenchem Co.,Ltd

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Adamas Reagent, Ltd.

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Accela ChemBio Co.,Ltd.

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Shanghai Longsheng chemical Co.,Ltd.

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View Lastest Price from 4-amino-2-fluoro-N-methylbenzamide manufacturers

Anhui Dexinjia Biopharm Co., Ltd

Product: N-Methyl-2-fluoro-4-aminobenzamide 915087-25-1
Price: US $15.00-50.00/kg
Min. Order: 1kg
Purity: NLT98%
Supply Ability: 5 ton per month
Release date: 2023-09-19

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 4-amino-2-fluoro-N-methylbenzamide 915087-25-1
Price: US $990.00-800.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-19

Wuhan Cell Pharmaceutical Co., Ltd

Product: 4-AMINO-2-FLUORO-N-METHYLBENZAMIDE 915087-25-1
Price: US $9.90-454.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2023-03-30

915087-25-1, 4-amino-2-fluoro-N-methylbenzamideRelated Search:

4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE 2-FLUORO-N-METHYL-4-NITROBENZAMIDE Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- [2H6]-Enzalutamide N-desMethyl EnzalutaMide Enzalutamide carboxylic acid Methyl 4-bromo-2-fluorobenzoate Enzalutamide 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-Bromo-2-fluorobenzoic acid methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate EnzalutaMide IMpurity Enzalutamide 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester

4-AMINO-2-FLUORO-N-METHYLBENZAMIDE

N-Methyl-2-fluoro-4-aminobenzamide

BenzaMide, 4-aMino-2-fluoro-N-Methyl-

2. 4-aMino-2-fluoro-N-MethylbenzaMide

N-Methyl-4-amino-2-fluoro-benzamide

4-amino-2-fluoro-N-menthylbenzamide

Enzalutamide Impurity 20

Enzalutamide ITS-3

N-Methyl-2-fluoro-4-AminobenzoylAmine

Enzalutamide Impurity 40

915087-25-1