N-desMethyl EnzalutaMide

Product Name: N-desMethyl EnzalutaMide
CAS No.: 1242137-16-1
Chemical Name: N-desMethyl EnzalutaMide
Synonyms: CS-1325;D3-EZ-TJXA;D3-EZLA-IM2;N-desmethyl MDV3100;N-desmethyl MDV-3100;N-desmethyl MDV 3100;Enzalutamide impurity O;Enzalutamide Impurity 2;Enzalutamide impurity B;Enzalutamide Impurity R
CBNumber: CB42667014
Molecular Formula: C20H14F4N4O2S
Formula Weight: 450.41
MOL File: 1242137-16-1.mol

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N-desMethyl EnzalutaMide Property

Melting point:: >230oC (dec.)
Boiling point:: 572.4±60.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Amber Vial, Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
pka: 14.86±0.50(Predicted)
form: Solid
color: White to Off-White
Stability:: Light Sensitive
InChI: InChI=1S/C20H14F4N4O2S/c1-19(2)17(30)27(11-4-3-10(9-25)14(7-11)20(22,23)24)18(31)28(19)12-5-6-13(16(26)29)15(21)8-12/h3-8H,1-2H3,(H2,26,29)
InChIKey: JSFOGZGIBIQRPU-UHFFFAOYSA-N
SMILES: C(N)(=O)C1=CC=C(N2C(=S)N(C3=CC=C(C#N)C(C(F)(F)F)=C3)C(=O)C2(C)C)C=C1F

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C987645
Product name: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide
Packaging: 10mg
Price: $185
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 68924
Product name: 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide
Packaging: 10mg
Price: $650
Updated: 2021/12/16

Chemenu

Product number: CM187544
Product name: 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide
Purity: 98%
Packaging: 100mg
Price: $694
Updated: 2021/12/16

Crysdot

Product number: CD31004126
Product name: N-desmethylEnzalutamide
Purity: 98+%
Packaging: 100mg
Price: $735
Updated: 2021/12/16

Crysdot

Product number: CD31004126
Product name: N-desmethylEnzalutamide
Purity: 98+%
Packaging: 50mg
Price: $432
Updated: 2021/12/16

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N-desMethyl EnzalutaMide Chemical Properties,Usage,Production

Uses

4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.

Uses

N-desMethyl EnzalutaMide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.

Definition

ChEBI: N-desmethylenzalutamide is a benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia. It has a role as an antineoplastic agent and an androgen antagonist. It is a member of benzamides, an imidazolidinone, a nitrile, a thiocarbonyl compound, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.

in vivo

N-desmethyl Enzalutamide is an active metabolite that is thought to contribute to the clinical effects of Enzalutamide because it demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as Enzalutamide. The carboxylic acid metabolite is pharmacologically inactive and circulates at approximately 25 % lower plasma concentrations than Enzalutamide^[1].

N-desMethyl EnzalutaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-desMethyl EnzalutaMide Suppliers

China 116 France 1 India 6 United States 10 Global 133

Arizest(Shanghai)Pharmatech Co.,Ltd

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J & K SCIENTIFIC LTD.

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Daicel Chiral Technologies (China)CO.,LTD

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Artis Chemistry (Shanghai) Co. Ltd.

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S.Z. PhyStandard Bio-Tech. Co., Ltd.

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Shanghai Famo Bio-chemical Technology Company Ltd.

Tel: 021-02136680027 15800370750
Email: 1706640024@qq.com
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View Lastest Price from N-desMethyl EnzalutaMide manufacturers

Hebei Xinsheng New Material Technology Co., LTD.

Product: N-desMethyl EnzalutaMide 1242137-16-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-09-06

Anhui Ruihan Technology Co., Ltd

Product: N-desMethyl EnzalutaMide 1242137-16-1
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000t/year
Release date: 2023-09-11

Career Henan Chemical Co

Product: N-desMethyl EnzalutaMide 1242137-16-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-12-18

1242137-16-1, N-desMethyl EnzalutaMideRelated Search:

Enzalutamide Enzalutamide Enzalutamide carboxylic acid Oxathiolan 5fu-.B. 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester EnzalutaMide IMpurity methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate 4-Bromo-2-fluorobenzoic acid 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Methyl 4-bromo-2-fluorobenzoate 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE [2H6]-Enzalutamide Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- 4-amino-2-fluoro-N-methylbenzamide

N-desMethyl EnzalutaMide

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluorobenzaMide

Enzalutamide impurity B

Enzalutamide Impurity 2

N-desmethyl MDV 3100

N-desmethyl MDV3100

N-desmethyl MDV-3100

N-DESMETHYL MDV3100;N-DESMETHYL MDV 3100;N-DESMETHYL MDV-3100

CS-1325

N-desmethyl MDV3100, N-desmethyl-Enzalutamide

Enzalutamide impurity O

Enzaluramide Impurities 2?

Enzalutamide N-Desmethyl Impurity

Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-

Enzalutamide Impurity R

N-desmethyl Enzalutamide (N-desmethyl MDV 3100)

N-Desmethyl Enzalutamide-d6Q: What is N-Desmethyl Enzalutamide-d6 Q: What is the CAS Number of N-Desmethyl Enzalutamide-d6 Q: What is the storage condition of N-Desmethyl Enzalutamide-d6 Q: What are the applications of N-Desmethyl Enzalutamide-d6

high quality N-desMethyl EnzalutaMide

4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2- thioxoimidazolidin-1-yl)-2-fluorobenzamide

D3-EZ-TJXA

D3-EZLA-IM2

N-desmethyl Enzalutamide, 10 mM in DMSO

Enzalutamidedemethylationimpurity

4- [3- [4-cyano-3- (trifluoromethyl) phenyl] -5,5-dimethyl-4-oxo-2-thio-1-imidazolyl] -2-fluorobenzamide

Enzalutamide Impurities 10269-1213

1242137-16-1

C20H14F4N4O2S

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