4-amino-2-fluoro-N-methylbenzamide

ChemicalBook > CAS DataBase List > 4-amino-2-fluoro-N-methylbenzamide

4-amino-2-fluoro-N-methylbenzamide

Product Name: 4-amino-2-fluoro-N-methylbenzamide
CAS No.: 915087-25-1
Chemical Name: 4-amino-2-fluoro-N-methylbenzamide
Synonyms: N-Methyl-2-fluoro-4-aminobenzamide;N-Methyl-4-amino-2-fluoro-benzamide;Enzalutamide ITS-3;Enzalutamide Impurity 40;Enzalutamide Impurity 20;4-AMINO-2-FLUORO-N-METHYLBENZAMIDE;4-amino-2-fluoro-N-menthylbenzamide;N-Methyl-2-fluoro-4-AminobenzoylAmine;2. 4-aMino-2-fluoro-N-MethylbenzaMide;BenzaMide, 4-aMino-2-fluoro-N-Methyl-
CBNumber: CB02452656
Molecular Formula: C8H9FN2O
Formula Weight: 168.17
MOL File: 915087-25-1.mol

Less

4-amino-2-fluoro-N-methylbenzamide Property

Melting point:: 160 - 163°C
Boiling point:: 320℃
Density: 1.234
Flash point:: 147℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.12±0.46(Predicted)
color: White to Off-White
Stability:: Moisture Sensitive
InChI: InChI=1S/C8H9FN2O/c1-11-8(12)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3,(H,11,12)
InChIKey: XOKAXPQJUODMSH-UHFFFAOYSA-N
SMILES: C(NC)(=O)C1=CC=C(N)C=C1F

Less

Safety

HS Code: 2924297099

Less

Hazard and Precautionary Statements (GHS)

Signal word: Warning

Less

N-Bromosuccinimide Price

TRC

Product number: A609743
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 25g
Price: $275
Updated: 2021/12/16

TRC

Product number: A609743
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 50g
Price: $520
Updated: 2021/12/16

AK Scientific

Product number: J95296
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Packaging: 100g
Price: $520
Updated: 2021/12/16

Matrix Scientific

Product number: 143913
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Purity: 95%
Packaging: 25g
Price: $1110
Updated: 2021/12/16

Matrix Scientific

Product number: 143913
Product name: 4-Amino-2-fluoro-N-methylbenzamide
Purity: 95%
Packaging: 5g
Price: $370
Updated: 2021/12/16

Less

4-amino-2-fluoro-N-methylbenzamide Chemical Properties,Usage,Production

Uses

4-amino-2-fluoro-N-methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors.

Description

4-amino-2-fluoro-N-methylbenzamide is a novel antiandrogen drug MDV (Marek's Disease Virus) 3100 key intermediate which is the new generation oral androgen antagonist medicine of united states drug developer Medivation company exploitation, be mainly used in treating advanced prostate cancer (CRPC) patient.

Preparation

2-fluoro-4-nitrotoluene as raw material, through potassium permanganate oxidation, the thionyl chloride chlorination, methylamine amination, and Pd/C hydrogenation reduction prepare 4-amino-2-fluoro-N-methylbenzamide.

4-amino-2-fluoro-N-methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-amino-2-fluoro-N-methylbenzamide Suppliers

Canada 1 China 204 India 15 Ukraine 1 United States 6 Global 227

Haohong (Qihe) Medical Technology Co., LTD

Tel: 18068541569 18660163165
Fax: 0519-85551569
Email: sale@inyelchem.com
Country: China
ProdList: 194
Advantage: 58

Beijing Sai Siyuan Biomedical Technology Co., Ltd.

Tel: 010-87925700 13522399152
Email: 1664478984@qq.com
Country: China
ProdList: 10
Advantage: 58

Anhui Dexinjia Biopharm Co., Ltd

Tel: 0531-82375887 13596650888
Email: 3385307203@qq.com
Country: China
ProdList: 296
Advantage: 58

Chemvon Biotechnology Co., Ltd

Tel: 021-50790412
Fax: +86-21-50790419
Email: info@chemvon.com
Country: China
ProdList: 371
Advantage: 57

ChemFuture PharmaTech (Jiangsu) Ltd

Tel: 5108538618
Fax: 86 510 85386988-8017
Email: suger.wang@chemfuture.com
Country: China
ProdList: 822
Advantage: 65

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel
Country: China
ProdList: 42982
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5700
Advantage: 66

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9900
Advantage: 58

China Shenyang Tyschem CO. ,LTD

Tel: 13889821340
Fax: 024-83607930
Email: tongyuansu@126.com
Country: China
ProdList: 126
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
Advantage: 50

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 15523000485
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1686
Advantage: 58

Hangzhou Dechem Tech Co.，Ltd

Tel: 86-0571-87649320
Fax: 86-0571-87649320
Email: dechem@aliyun.com
Country: China
ProdList: 163
Advantage: 58

Jiaxing Novartis Chemical Co., Ltd.

Tel: 18957373295
Fax: -
Country: China
ProdList: 1580
Advantage: 58

Shanghai SE Pharm Co., Ltd

Tel: 18112588827
Email: sales4@sepharm.com.cn
Country: China
ProdList: 307
Advantage: 60

Shanghai AQBioPharma Co., Ltd.

Tel: 13764862135
Fax: 51370935-8011
Email: yaoliang.ni@aqbiopharma.com.cn
Country: China
ProdList: 2715
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Hangzhou J&H Chemical Co., Ltd.

Tel: +86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 10015
Advantage: 53

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5943
Advantage: 50

AN PharmaTech Co Ltd

Tel: 86(21)68097365
Fax: 86(21)33321566
Email: sales@anpharma.net
Country: China
ProdList: 4901
Advantage: 55

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Shanghai eliv pharmaceutical Co.,Ltd.

Tel: 021-50158063
Fax: 021-6153 1846
Email: sales@elivpharma.com
Country: China
ProdList: 632
Advantage: 58

Shanghai Rochi Pharmaceutical Co., Ltd.

Tel: 021-38751876 15000076078
Fax: 021-50275764
Email: Info@rochipharma.com
Country: China
ProdList: 561
Advantage: 55

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1745
Advantage: 55

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: sales@chemwill.com
Country: China
ProdList: 1975
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3496
Advantage: 58

AgileBioChem Co., Ltd.

Tel: 18055517827
Email: sales@agilebiochem.com
Country: China
ProdList: 1000
Advantage: 50

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9934
Advantage: 55

Changzhou Zhichao Chemical Co., Ltd.

Tel: 0519-85556809
Fax: 0519-85556810
Email: info@wisdomdrugs.com
Country: China
ProdList: 216
Advantage: 55

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 9859
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Jiangsu C-jun Biotechnology Co., Ltd.

Tel: +86 (519) 8969-7536
Fax: +86 (519) 8988-9226
Email: sales3@cjxrpharm.com
Country: China
ProdList: 218
Advantage: 58

Shanghai Qiandu Biological Technology Co., Ltd.

Tel: 021-61535850
Email: 2911799694@qq.com
Country: China
ProdList: 208
Advantage: 58

Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

Tel: 027-65526929 15102793023
Fax: 027-65526669
Email: hbhxry@163.com
Country: China
ProdList: 2060
Advantage: 55

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9190
Advantage: 65

Sichuan jiayinglai technology CO.,LTD

Tel: 028-028-64159575 13096309087
Fax: QQ3213375147
Email: 1678230860@qq.com
Country: China
ProdList: 2348
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28821
Advantage: 58

LinkChem Co.,Ltd.

Tel: 021-021-58950110 13124863828
Fax: 021-20922272
Email: sales@linkchem.cn
Country: China
ProdList: 3000
Advantage: 58

Cymtek Laboratories, Limited.

Tel: +86 (519) 8109-0216
Fax: +86 (519) 8188-9216
Country: China
ProdList: 907
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: 571-85586718 +8613336195806
Fax: +86-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 29797
Advantage: 60

Aikon International Limited

Tel: 025-66028182 18112977050
Fax: (3)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 15820
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 18521078705
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 19944
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17997
Advantage: 58

Less

View Lastest Price from 4-amino-2-fluoro-N-methylbenzamide manufacturers

Wuhan Cell Pharmaceutical Co., Ltd

Product: 4-AMINO-2-FLUORO-N-METHYLBENZAMIDE 915087-25-1
Price: US $9.90-454.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2023-03-30

Anhui Dexinjia Biopharm Co., Ltd

Product: N-Methyl-2-fluoro-4-aminobenzamide 915087-25-1
Price: US $15.00-50.00/kg
Min. Order: 1kg
Purity: NLT98%
Supply Ability: 5 ton per month
Release date: 2023-09-19

Shanghai Joiny Pharmaceutical Co.,LTD

Product: N-Methyl-2-fluoro-4-aminobenzamide 915087-25-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 5500kg
Release date: 2023-09-12

915087-25-1, 4-amino-2-fluoro-N-methylbenzamideRelated Search:

4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE 2-FLUORO-N-METHYL-4-NITROBENZAMIDE Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- [2H6]-Enzalutamide N-desMethyl EnzalutaMide Enzalutamide carboxylic acid Methyl 4-bromo-2-fluorobenzoate Enzalutamide 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-Bromo-2-fluorobenzoic acid methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate EnzalutaMide IMpurity Enzalutamide 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester

4-AMINO-2-FLUORO-N-METHYLBENZAMIDE

N-Methyl-2-fluoro-4-aminobenzamide

BenzaMide, 4-aMino-2-fluoro-N-Methyl-

2. 4-aMino-2-fluoro-N-MethylbenzaMide

N-Methyl-4-amino-2-fluoro-benzamide

4-amino-2-fluoro-N-menthylbenzamide

Enzalutamide Impurity 20

Enzalutamide ITS-3

N-Methyl-2-fluoro-4-AminobenzoylAmine

Enzalutamide Impurity 40

915087-25-1