ChemicalBook > CAS DataBase List > 2-(4-BROMO-PHENYL)-THIAZOLE

2-(4-BROMO-PHENYL)-THIAZOLE

Product Name
2-(4-BROMO-PHENYL)-THIAZOLE
CAS No.
27149-27-5
Chemical Name
2-(4-BROMO-PHENYL)-THIAZOLE
Synonyms
2-(4-BROMO-PHENYL)-THIAZOLE;Thiazole, 2-(4-bromophenyl)-;2-(4-bromophenyl)-1,3-thiazole
CBNumber
CB92453515
Molecular Formula
C9H6BrNS
Formula Weight
240.12
MOL File
27149-27-5.mol
More
Less

2-(4-BROMO-PHENYL)-THIAZOLE Property

Melting point:
52-53 °C
Boiling point:
324.3±44.0 °C(Predicted)
Density 
1.563±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
1.92±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
1142AJ
Product name
2-(4-Bromophenyl)-1,3-thiazole
Packaging
100mg
Price
$95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0069450
Product name
2-(4-BROMO-PHENYL)-THIAZOLE
Purity
97.00%
Packaging
1G
Price
$632.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0069450
Product name
2-(4-BROMO-PHENYL)-THIAZOLE
Purity
97.00%
Packaging
2.5G
Price
$1473.14
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0069450
Product name
2-(4-BROMO-PHENYL)-THIAZOLE
Purity
97.00%
Packaging
5G
Price
$1928.08
Updated
2021/12/16
Ambeed
Product number
A155832
Product name
2-(4-Bromophenyl)thiazole
Purity
98%
Packaging
100mg
Price
$69
Updated
2021/12/16
More
Less

2-(4-BROMO-PHENYL)-THIAZOLE Chemical Properties,Usage,Production

Synthesis

3034-53-5

589-87-7

27149-27-5

GENERAL STEPS: 2-Bromothiazole (16.4 g) was dissolved in 50 ml of THF under nitrogen protection and cooled in an ice bath. 55 ml of 2M isopropylmagnesium chloride solution in THF was slowly added dropwise while stirring. After the dropwise addition was completed, stirring of the reaction mixture was continued for 1 hour. Subsequently, zinc chloride-tetramethylethylenediamine complex (30.3 g) was added and stirred at room temperature for 1 hour. Next, 1-bromo-4-iodobenzene (28.3 g) and Pd(PPh3)4 (3.5 g) were added, heated to reflux temperature and stirred for 1.5 hours. After completion of the reaction, it was cooled to room temperature. To remove metal ions from the catalyst, about 2 times the molar amount of ethylenediaminetetraacetic acid disodium salt (EDTA-4Na) aqueous solution was added. Subsequently, the organic phase was separated by extraction with toluene and the solvent was removed by distillation under reduced pressure. Finally, the target product 2-(4-bromophenyl)thiazole (18.3 g) was purified by silica gel column chromatography (eluent: toluene/ethyl acetate = 50/1, v/v).

References

[1] Patent: KR2015/138163, 2015, A. Location in patent: Paragraph 0333; 0334

2-(4-BROMO-PHENYL)-THIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-(4-BROMO-PHENYL)-THIAZOLE Suppliers

China 29 India 1 United States 2 Global 32
Suzhou Laing Biological Technology Co., LTD
Tel
0512-62968256 18550502935
Fax
0512-62968256
Email
export@laingbiotec.com
Country
China
ProdList
981
Advantage
58
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Yancheng Schiemann Biological Technology Co.,Ltd
Tel
515-88280676 18921872653
Email
sales@ximanbio.com
Country
China
ProdList
1524
Advantage
56
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
BePharm Ltd
Tel
400-685-9117
Fax
021-51816740
Email
market@bepharm.com
Country
China
ProdList
15081
Advantage
60
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12475
Advantage
58
Shanghai Huaxing Biological Technology Co., Ltd.
Tel
18621295758
Fax
-QQ:1449085402
Email
1449085402@qq.com
Country
China
ProdList
1817
Advantage
55
Shanghai Anmike Chemical Co. Ltd.
Tel
微信 17321281695 18019252918
Fax
021-31261685
Email
sale@amkchem.com
Country
China
ProdList
9405
Advantage
55
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60

27149-27-5, 2-(4-BROMO-PHENYL)-THIAZOLERelated Search:

2-(4-BROMOPHENYL)THIAZOLE-5-CARBALDEHYDE 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-THIAZOLO[4,5-C]PYRIDINE 2-(4-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 1-(2-BENZOTHIAZOLYL)-4-BROMOBENZENE 2-(4-BROMO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID 2-(4-BROMO-PHENYL)-THIAZOLE-4-CARBALDEHYDE C-[2-(4-BROMO-PHENYL)-THIAZOL-4-YL]-METHYLAMINE 2-(4-BROMO-PHENYL)-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDINE [2-(4-BROMO-PHENYL)-THIAZOL-4-YL]-METHANOL 2-(4-BROMO-2-METHYL-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 2-(4-BROMO-PHENYL)-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 3-(1,3-BENZOTHIAZOL-2-YL)-2,6-DIBROMO-4-CHLOROANILINE 2-(4-BROMO-2-METHYL-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID 2-(4-BROMO-3-METHOXY-PHENYL)-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 2-(4-BROMO-3-METHOXY-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID 2-(4-BROMO-PHENYL)-THIAZOLE-5-CARBOXYLIC ACID 2-(4-BROMO-2-METHYL-PHENYL)-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 4-BROMOMETHYL-2-(4-BROMO-PHENYL)-THIAZOLE

  • 2-(4-BROMO-PHENYL)-THIAZOLE
  • Thiazole, 2-(4-bromophenyl)-
  • 2-(4-bromophenyl)-1,3-thiazole
  • 27149-27-5