7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
- Product Name
- 7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
- CAS No.
- 93587-23-6
- Chemical Name
- 7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
- Synonyms
- 7-Bromo-1H-pyrrolo[3,2-d]pyrimidin-4(5H);7-broMo-1H-pyrrolo[3,2-d]pyriMidin-4(5H)-one;7-bromo-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one;7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE;4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-bromo-3,5-dihydro-
- CBNumber
- CB92453757
- Molecular Formula
- C6H4BrN3O
- Formula Weight
- 214.02
- MOL File
- 93587-23-6.mol
7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Property
- storage temp.
- 2-8°C
- Appearance
- White to off-white Solid
N-Bromosuccinimide Price
- Product number
- B691408
- Product name
- 7-Bromo-1,5-dihydro-4h-pyrrolo[3,2-d]pyrimidin-4-one
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB142179
- Product name
- 7-Bromo-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB142179
- Product name
- 7-Bromo-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
- Packaging
- 250mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- W9624
- Product name
- 7-Bromo-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
- Packaging
- 250mg
- Price
- $201
- Updated
- 2021/12/16
- Product number
- FB142179
- Product name
- 7-Bromo-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
- Packaging
- 500mg
- Price
- $275
- Updated
- 2021/12/16
7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Chemical Properties,Usage,Production
Synthesis
5655-01-6
93587-23-6
The general procedure for the synthesis of 7-bromo-1,5-dihydro-4H-pyrrolo[3,2-D]pyrimidin-4-one using pyrrolo[3,2-D]pyrimidin-4-one as starting material was as follows: pyrrolo[3,2-D]pyrimidin-4-one (1.70 g, 12.6 mmol) and N-bromosuccinimide (NBS, 2.69 g, 15.1 mmol) were dissolved in N ,N-dimethylformamide (DMF, 100 mL) and the reaction was stirred at room temperature for 18 hours. Upon completion of the reaction, the reaction mixture was diluted with deionized water (50 mL) and the precipitated solid product was collected by filtration. The resulting solid was dried, suspended in methanol (MeOH) and filtered again for purification. Finally, the filtrate was concentrated under reduced pressure to afford the target compound 7-bromo-1,5-dihydro-4H-pyrrolo[3,2-D]pyrimidin-4-one as a beige solid (2.60 g, 97% yield). The product was analyzed by liquid chromatography-mass spectrometry (LCMS) and the molecular weights of the products were confirmed (ES+): 213.9, 215.9 ([M+H]+).
References
[1] Patent: US2013/102587, 2013, A1. Location in patent: Paragraph 0271; 0272
7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE Preparation Products And Raw materials
Raw materials
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View Lastest Price from 7-BROMO-1,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE manufacturers
- Product
- 7-Bromo-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one 93587-23-6
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-26