7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE

Product Name: 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE
CAS No.: 168123-82-8
Chemical Name: 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE
Synonyms: 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE;7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione;7-broMo-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-2,3-dione;7-Bromo-2,3-dioxo-1,4-dihydro-pyrido[2,3-b]pyrazine;Pyrido[2,3-b]pyrazine-2,3-dione, 7-bromo-1,4-dihydro-;7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE ISO 9001：2015 REACH
CBNumber: CB0335319
Molecular Formula: C7H4BrN3O2
Formula Weight: 242.03
MOL File: 168123-82-8.mol

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7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE Property

Density: 1.851±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 7.95±0.20(Predicted)
Appearance: Brown to gray Solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B698903
Product name: 7-Bromopyrido[2,3-b]pyrazine-2,3(1h,4h)-dione
Packaging: 25mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154325
Product name: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione
Packaging: 100mg
Price: $78
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154325
Product name: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione
Packaging: 250mg
Price: $155
Updated: 2021/12/16

AK Scientific

Product number: W3663
Product name: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione
Packaging: 250mg
Price: $163
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154325
Product name: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione
Packaging: 500mg
Price: $270
Updated: 2021/12/16

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7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE Chemical Properties,Usage,Production

Synthesis

38875-53-5

95-92-1

168123-82-8

General procedure for the synthesis of 7-bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione from 2,3-diamino-5-bromopyridine and diethyl oxalate: a mixture of 2,3-diamino-5-bromopyridine (1 mmol) and diethyl oxalate (10 mL) was heated and refluxed for 4 hours. After completion of the reaction, it was cooled to room temperature. The resulting solid was collected by filtration and washed sequentially with ethyl acetate and 95% ethanol. Subsequently, the solid was decolorized using activated charcoal and recrystallized in a solvent mixture of water and DMF or DMSO to afford 7-bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione as a white solid (620 mg, 25.6% yield). The product was characterized by IR (KBr) ν 31199, 3138, 3045, 2751, 1715, 1603, 1446, 1389 cm-1; 1H NMR (400 MHz, DMSO-d6) δ 7.55 (1H, d, J = 1.6 Hz, H-6), 8.15 (1H, d, J = 1.6 Hz, H-8); 13C NMR (100 MHz, DMSO-d6) δ 112.36, 123.20, 123.80, 138.46, 141.83, 154.55, 155.58; HRMS-EI C7H4BrN3O2 calculated value [M + H]+ 241.9565, measured value 241.9567.

References

[1] European Journal of Medicinal Chemistry, 2016, vol. 117, p. 19 - 32
[2] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 308 - 317
[3] Journal of Medicinal Chemistry, 2018, vol. 61, # 7, p. 2949 - 2961

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE Preparation Products And Raw materials

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7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE Suppliers

China 49 Germany 1 India 2 United Kingdom 2 United States 7 Global 61

Pure Chemistry Scientific Inc.

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View Lastest Price from 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE manufacturers

Dideu Industries Group Limited

Product: 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE 168123-82-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-23

Shaanxi Dideu Medichem Co. Ltd

Product: 7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione 168123-82-8
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-12

168123-82-8, 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONERelated Search:

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7-Bromo-2,3-dioxo-1,4-dihydro-pyrido[2,3-b]pyrazine

7-broMo-1H,2H,3H,4H-pyrido[2,3-b]pyrazine-2,3-dione

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE

7-bromo-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione

Pyrido[2,3-b]pyrazine-2,3-dione, 7-bromo-1,4-dihydro-

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE ISO 9001：2015 REACH

168123-82-8