5-BROMO-N-METHYLPYRIDIN-2-AMINE

Product Name: 5-BROMO-N-METHYLPYRIDIN-2-AMINE
CAS No.: 84539-30-0
Chemical Name: 5-BROMO-N-METHYLPYRIDIN-2-AMINE
Synonyms: 2-(Methylamino)-5-bromopyridine;5-BROMO-N-METHYLPYRIDIN-2-AMINE;N-Methyl-5-bromopyridine-2-amine;5-Bromo-N-methylpyridin-2-ylamine;2-PyridinaMine, 5-broMo-N-Methyl-;5-Bromo-2-(N-methylamino)pyridine;5-bromo-N-methyl-2-pyridinamine(SALTDATA: FREE)
CBNumber: CB3783791
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 84539-30-0.mol

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5-BROMO-N-METHYLPYRIDIN-2-AMINE Property

Melting point:: 70-71 °C
Boiling point:: 245℃
Density: 1.581
Flash point:: 102℃
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 5.00±0.10(Predicted)
color: White to Off-White

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Safety

RIDADR: UN2811
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: B685643
Product name: 5-Bromo-2-(N-methylamino)pyridine
Packaging: 1g
Price: $85
Updated: 2021/12/16

Matrix Scientific

Product number: 052704
Product name: 5-Bromo-N-methyl-2-pyridinamine
Packaging: 2.500g
Price: $104
Updated: 2021/12/16

AK Scientific

Product number: W8725
Product name: 5-Bromo-N-methylpyridin-2-amine
Packaging: 1g
Price: $116
Updated: 2021/12/16

Matrix Scientific

Product number: 052704
Product name: 5-Bromo-N-methyl-2-pyridinamine
Packaging: 500mg
Price: $33
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140719
Product name: 5-Bromo-N-methylpyridin-2-amine
Packaging: 1g
Price: $83
Updated: 2021/12/16

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5-BROMO-N-METHYLPYRIDIN-2-AMINE Chemical Properties,Usage,Production

Uses

5-Bromo-2-(N-methylamino)pyridine is useful for the synthetic preparation of halo aminopyridines.

Synthesis

1072-97-5

74-88-4

84539-30-0

26163-07-5

a) Synthesis of 5-bromo-2-(methylamino)pyridine and 5-bromo-2-(dimethylamino)pyridine To an anhydrous DMF (40 mL) suspension of NaH (60% dispersed in mineral oil, 0.44 g, 11 mmol), solid 2-amino-5-bromopyridine (1.73 g, 10 mmol) was added in batches, with the addition process being controlled to be completed within 5-10 min. After the gas release slowed down, the resulting amber colored mixture was stirred for 15 minutes. Subsequently, iodomethane (0.61 mL, 10 mmol) was added all at once. The reaction mixture was stirred overnight at room temperature, after which it was concentrated under vacuum. The residue was diluted with 5% aqueous NH4Cl (30 mL) and extracted with CH2Cl2. The organic phases were combined, washed with brine, dried (MgSO4) and concentrated. The product was separated by rapid chromatography on silica gel (3% MeOH/CH2Cl2). 5-Bromo-2-(methylamino)pyridine (0.60 g, 32%) was obtained as a semi-solid: TLC (3% MeOH/CH2Cl2) Rf 0.35; MS (ES) m/e 187 (M + H)+. Also obtained was 5-bromo-2-(dimethylamino)pyridine (0.70 g, 34%) as a semi-solid: TLC (3% MeOH/CH2Cl2) Rf 0.77; MS (ES) m/e 201 (M + H)+.

References

[1] Patent: EP1226138, 2004, B1

5-BROMO-N-METHYLPYRIDIN-2-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-N-METHYLPYRIDIN-2-AMINE Suppliers

China 66 India 1 Russia 1 Switzerland 1 Ukraine 1 United Kingdom 1 United States 7 Global 78

Tetranov Biopharm

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Shanghai Hong-chuang Pharma Tech Co., Ltd.

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View Lastest Price from 5-BROMO-N-METHYLPYRIDIN-2-AMINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-N-METHYLPYRIDIN-2-AMINE 84539-30-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-N-METHYLPYRIDIN-2-AMINE 84539-30-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

84539-30-0, 5-BROMO-N-METHYLPYRIDIN-2-AMINERelated Search:

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE 5-Bromo-2-(dimethylamino)pyridine 2-ACETYLAMINO-5-BROMOPYRIDINE N-(5-BROMOPYRIDIN-2-YL)-2-CHLOROACETAMIDE Benzenebutanamide, N-(5-bromo-2-pyridinyl)-alpha,gamma-dioxo-4-methyl- N-(5-BROMO-2-PYRIDINYL)-4-IODO-BENZAMIDE 5-Bromo-2-(piperidin-1-yl)pyridine 2-(((5-BROMO-3-METHYL-2-PYRIDYL)AMINO)METHYL)PHENOL 2-(((5-BROMO(2-PYRIDYL))AMINO)METHYLENE)-5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE N-(5-BROMO-PYRIDIN-2-YL)-SUCCINAMIC ACID N-(5-BROMO(2-PYRIDYL))(3-(2-CHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)FORMAMIDE N-(5-BROMO-3-METHYL-2-PYRIDINYL)-N'-(2,4-DIFLUOROPHENYL)THIOUREA 5-bromo-N-[(2-chlorophenyl)methyl]pyridin-2-amine 2-([(5-BROMO-3-METHYL-2-PYRIDINYL)AMINO]METHYL)-6-METHOXYBENZENOL AURORA KA-375 (((5-BROMO-2-PYRIDYL)AMINO)METHYLENE)METHANE-1,1-DICARBONITRILE 2-(((5-BROMO-2-PYRIDYL)AMINO)METHYLENE)INDANE-1,3-DIONE N-(5-BROMO(2-PYRIDYL))-2-INDOL-3-YL-2-OXOETHANAMIDE

5-BROMO-N-METHYLPYRIDIN-2-AMINE

5-Bromo-2-(N-methylamino)pyridine

5-bromo-N-methyl-2-pyridinamine(SALTDATA: FREE)

2-(Methylamino)-5-bromopyridine

N-Methyl-5-bromopyridine-2-amine

2-PyridinaMine, 5-broMo-N-Methyl-

5-Bromo-N-methylpyridin-2-ylamine

84539-30-0