2-ACETYLAMINO-5-BROMOPYRIDINE

Product Name: 2-ACETYLAMINO-5-BROMOPYRIDINE
CAS No.: 7169-97-3
Chemical Name: 2-ACETYLAMINO-5-BROMOPYRIDINE
Synonyms: SKL873;2-ACETAMIDO-5-BROMOPYRIDINE;N-ACETYLAMINO-5-BROMOPYRIDINE;2-ACETYLAMINO-5-BROMOPYRIDINE;2-Acetamido-5-bromopyridine >2-Acetylamino-5-bromopyridine, 98%;N-(5-BROMO-PYRIDIN-2-YL)-ACETAMIDE;Acetamide, N-(5-bromo-2-pyridinyl)-;2-ACETYLAMINO-5-BROMOPYRIDINE, PURISS, 98%;JR-8242, 2-Acetylamino-5-bromopyridine, 97%
CBNumber: CB7459508
Molecular Formula: C7H7BrN2O
Formula Weight: 215.05
MOL File: 7169-97-3.mol

More

Less

2-ACETYLAMINO-5-BROMOPYRIDINE Property

Melting point:: 175-179 °C (lit.)
Boiling point:: 372.2±27.0 °C(Predicted)
Density: 1.630±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 12.94±0.70(Predicted)
color: White to Light yellow
CAS DataBase Reference: 7169-97-3(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn,T
Risk Statements: 22-36/37/38-43-40
Safety Statements: 26-36/37/39-22
WGK Germany: 3
HS Code: 29339900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 646407
Product name: 2-Acetylamino-5-bromopyridine
Purity: 98%
Packaging: 1g
Price: $30.3
Updated: 2023/01/07

Sigma-Aldrich

Product number: 646407
Product name: 2-Acetylamino-5-bromopyridine
Purity: 98%
Packaging: 10g
Price: $193
Updated: 2023/01/07

TCI Chemical

Product number: A2375
Product name: 2-Acetamido-5-bromopyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: A2375
Product name: 2-Acetamido-5-bromopyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TRC

Product number: A143500
Product name: 2-Acetamido-5-bromopyridine
Packaging: 25g
Price: $120
Updated: 2021/12/16

More

Less

2-ACETYLAMINO-5-BROMOPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

2-Acetamido-5-bromopyridine is a chemical reagent used in the synthesis of novel Bcr-Abl inhibitors with diacylated piperazine felxible linkers. Also used to produce hetero-monocyclic derivatives as even more potent inhibitors of BCR-ABL.

Synthesis

1072-97-5

108-24-7

7169-97-3

2-Amino-5-bromopyridine (86.50 g, 500 mmol), acetic anhydride (153 g, 1500 mmol) and 850 mL of acetic acid were added to a 2000 mL single-necked round-bottomed flask with a magnetic stirrer turned on. The reaction mixture was stirred at 100 °C for 9 hours. After confirming the complete reaction of 2-amino-5-bromopyridine by thin layer chromatography (TLC) and gas chromatography (GC) monitoring, water was added to the reaction solution. Subsequently, the reaction was filtrated and the filter cake was washed with a solvent mixture of ethyl acetate and n-hexane (1:4, v/v) to obtain the pure product 2-acetamido-5-bromopyridine. The filtrate was extracted with ethyl acetate, and the extract was concentrated by rotary evaporation to obtain the crude product, which was recrystallized with a mixed solvent of ethyl acetate and hexane (1:4, v/v) and further purified to obtain 2-acetamido-5-bromopyridine. The product was dried and the calculated yield was 75.40%, and the purity was 99.68% as determined by high performance liquid chromatography (HPLC).

References

[1] Patent: CN103601745, 2017, B. Location in patent: Paragraph 0029; 0030
[2] Tetrahedron Letters, 2002, vol. 43, # 17, p. 3121 - 3123
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 205
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0480; 0481
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0414

2-ACETYLAMINO-5-BROMOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-ACETYLAMINO-5-BROMOPYRIDINE Suppliers

Americas 1 China 115 Europe 1 Germany 3 India 17 Japan 1 Switzerland 1 United Kingdom 7 United States 33 Global 179

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

More

Less

View Lastest Price from 2-ACETYLAMINO-5-BROMOPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 2-ACETYLAMINO-5-BROMOPYRIDINE 7169-97-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-20

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Acetylamino-5-bromopyridine 7169-97-3
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-12

Career Henan Chemical Co

Product: 2-ACETYLAMINO-5-BROMOPYRIDINE 7169-97-3
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-14

7169-97-3, 2-ACETYLAMINO-5-BROMOPYRIDINERelated Search:

6-Acetylamino-3-bromopyridine-2-carboxylic acid 2-ACETYLAMINO-5-BROMOPYRIDINE 7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE 4-(Acetylamino)-3-bromopyridine N-(5-BROMO-2-PYRIDINYL)-4-METHYL-BENZAMIDE N-(5-BROMO-2-PYRIDINYL)-BENZAMIDE N-(5-BROMOPYRIDIN-2-YL)-2-CHLOROACETAMIDE BENZAMIDE, N-(5-BROMO-2-PYRIDINYL)-4-CHLORO N-(5-BROMO-2-PYRIDINYL)-4-IODO-BENZAMIDE Benzenebutanamide, N-(5-bromo-2-pyridinyl)-alpha,gamma-dioxo-4-methyl- 3-(Acetylamino)-5-bromopyridine N-(5-BROMO(2-PYRIDYL))(3-(2-CHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)FORMAMIDE N-(5-BROMO-PYRIDIN-2-YL)-SUCCINAMIC ACID SALOR-INT L140813-1EA N-(5-BROMO-2-PYRIDINYL)-4-ETHYL-BENZAMIDE N-(5-BROMO(2-PYRIDYL))-2-INDOL-3-YL-2-OXOETHANAMIDE AURORA KA-373 (3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL)-N-(5-BROMO(2-PYRIDYL))FORMAMIDE

N-ACETYLAMINO-5-BROMOPYRIDINE

N-(5-BROMO-PYRIDIN-2-YL)-ACETAMIDE

2-ACETYLAMINO-5-BROMOPYRIDINE, PURISS, 98%

2-ACETAMIDO-5-BROMOPYRIDINE

2-ACETYLAMINO-5-BROMOPYRIDINE

Acetamide, N-(5-bromo-2-pyridinyl)-

JR-8242, 2-Acetylamino-5-bromopyridine, 97%

2-Acetamido-5-bromopyridine &gt

2-ACETYLAMINO-5-BROMOPYRIDINE ISO 9001：2015 REACH

SKL873

2-Acetylamino-5-bromopyridine, 98%

7169-97-3

Building Blocks

C8 to C9

Carbonyl Compounds

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Esters

Organic Building Blocks

pharmacetical

Pyridine

C8 to C9

Carbonyl Compounds

Esters

C7 and C8Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines