N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine

Product Name: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine
CAS No.: 199522-66-2
Chemical Name: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine
Synonyms: N1-(5-Bromopyrid-2-yl);N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine;N1-(5-Bromo-2-pyridinyl)-1,2-ethanediamine;1,2-Ethanediamine, N1-(5-bromo-2-pyridinyl)-
CBNumber: CB31501679
Molecular Formula: C7H10BrN3
Formula Weight: 216.08
MOL File: 199522-66-2.mol

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N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine Property

Boiling point:: 327.5±37.0 °C(Predicted)
Density: 1.560±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 9.06±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 150536
Product name: N1-(5-Bromopyridin-2-yl)ethane-1,2-diamine
Purity: 95%
Packaging: 1g
Price: $178
Updated: 2021/12/16

Matrix Scientific

Product number: 150536
Product name: N1-(5-Bromopyridin-2-yl)ethane-1,2-diamine
Purity: 95%
Packaging: 5g
Price: $474
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0028073
Product name: N-(5-BROMOPYRIDIN-2-YL)ETHANE-1,2-DIAMINE
Purity: 95.00%
Packaging: 5MG
Price: $501.5
Updated: 2021/12/16

AK Scientific

Product number: 0255AB
Product name: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine
Packaging: 5g
Price: $658
Updated: 2021/12/16

Chemenu

Product number: CM173451
Product name: N1-(5-Bromopyridin-2-yl)ethane-1,2-diamine
Purity: 95%
Packaging: 10g
Price: $716
Updated: 2021/12/16

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N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine Chemical Properties,Usage,Production

Synthesis

624-28-2

107-15-3

199522-66-2

The general procedure for the synthesis of N1-(5-bromopyridin-2-yl)ethane-1,2-diamine from 2,5-dibromopyridine and ethylenediamine was as follows: 1 g (4.22 mmol) of 2,5-dibromopyridine was dissolved in 10 mL of ethylenediamine, and the resulting solution was stirred and reacted for 15 hours at 100 °C. Upon completion of the reaction, the mixture was cooled to room temperature and the excess ethylenediamine was removed by distillation under reduced pressure. Subsequently, the concentrate was diluted by adding 50 mL of dichloromethane to the concentrate and the diluted solution was washed with 30 mL of distilled water. The aqueous phase was extracted twice with 50 mL of dichloromethane to recover the residual organic product. All organic layers were combined, dried with anhydrous sodium sulfate, and then concentrated under reduced pressure to afford 0.89 g (4.12 mmol) of the target compound N1-(5-bromopyridin-2-yl)ethane-1,2-diamine as a light yellow liquid in 98% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.10 (d, J = 1.6 Hz, 1H), 7.45 (dd, J1 = 8.8 Hz, J2 = 2.4 Hz, 1H), 6.33 (d, J = 8.8 Hz, 1H), 4.95 (brs, 1H), 3.34 (q, J = 6 Hz, 2H), 2.94 (t , J = 6 Hz, 2H).

References

[1] Patent: EP2692727, 2014, A2. Location in patent: Paragraph 0102-0103
[2] Patent: US2014/179691, 2014, A1. Location in patent: Paragraph 0112-0114
[3] Journal of Medicinal Chemistry, 1998, vol. 41, # 24, p. 4693 - 4705
[4] Patent: WO2017/106064, 2017, A1. Location in patent: Page/Page column 60

N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine Suppliers

China 16 India 1 United States 4 Global 21

Shanghai Hanhong Scientific Co.,Ltd.

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199522-66-2, N1-(5-Bromopyrid-2-yl)ethane-1,2-diamineRelated Search:

7-BROMOPYRIDO[2,3-B]PYRAZINE-2,3(1H,4H)-DIONE 5-BROMO-2-(PIPERAZIN-1-YL)PYRIDINE 5-BROMO-2-(4-BOC-PIPERAZIN-1-YL)-3-METHYLPYRIDINE 4-BOC-1-(5-BROMO-2-PYRIDYL)PIPERAZINE 5-Bromo-2-(piperazin-1-yl)-4-methylpyridine 7-BROMO-3,4-DIHYDROPYRIDO[2,3-B]PYRAZIN-2(1H)-ONE 1-(5-Bromo-2-pyridinyl)-1,4-diazepane 5-Bromo-2-(4-Boc-piperazin-1-yl)-4-methylpyridine 2-[4-(5-Bromo-2-pyridinyl)-1-piperazinyl]ethanol 5-BROMO-2-(PIPERAZIN-1-YL)-3-METHYLPYRIDINE 2-N-(2-AMINOETHYL)-AMINO-5-BROMOPYRIDINE DIHYDROCHLORIDE N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine 4-BROMO-1-(PIPERAZIN-1-YL)ISOQUINOLINE 5-Bromo-2-(4-Boc-piperazin-1-yl)pyridine 4-(5-BROMO-2-PYRIDINYL)-1-[(5-(2-PYRIMIDINYL)-2-[(METHYLSULFONYL)METHYL]-PENTYL)SULFONYL]-PIPERAZINE 5-BROMO-4,6-DIMETHYL-2-(4-METHYLPIPERAZINO)NICOTINONITRILE 7-BROMO-8-METHYL-3,4-DIHYDROPYRIDO[2,3-B]PYRAZIN-2(1H)-ONE (5-Bromo-3-nitro-pyridin-2-yl)-[2-(4-methyl-piperazin-1-yl)-ethyl]-amine

N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine

1,2-Ethanediamine, N1-(5-bromo-2-pyridinyl)-

N1-(5-Bromo-2-pyridinyl)-1,2-ethanediamine

N1-(5-Bromopyrid-2-yl)

199522-66-2

amine| alkyl bromide

pharmacetical