ChemicalBook > CAS DataBase List > 2,4-DICHLORO-6-METHYLQUINAZOLINE

2,4-DICHLORO-6-METHYLQUINAZOLINE

Product Name
2,4-DICHLORO-6-METHYLQUINAZOLINE
CAS No.
39576-82-4
Chemical Name
2,4-DICHLORO-6-METHYLQUINAZOLINE
Synonyms
EOS-60385;6-Methyl-2,4-dichloroquinazoline;2,4-DICHLORO-6-METHYLQUINAZOLINE;Quinazoline, 2,4-dichloro-6-methyl-;2,4-Dichloro-6-methylquinazoline,97%;2,4-Dichloro-6-methylquinazoline 97%
CBNumber
CB92454633
Molecular Formula
C9H6Cl2N2
Formula Weight
213.06
MOL File
39576-82-4.mol
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2,4-DICHLORO-6-METHYLQUINAZOLINE Property

Boiling point:
292.4±33.0 °C(Predicted)
Density 
1.418±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-0.30±0.30(Predicted)
form 
Solid
Appearance
White to off-white Solid
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Safety

HS Code 
2933992000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
D482990
Product name
2,4-dichloro-6-methylquinazoline
Packaging
50mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
089534
Product name
2,4-Dichloro-6-methylquinazoline
Packaging
1g
Price
$174
Updated
2021/12/16
Apolloscientific
Product number
OR302328
Product name
2,4-Dichloro-6-methylquinazoline
Purity
97%
Packaging
250mg
Price
$95
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-AN
Product name
2,4-Dichloro-6-methyl-quinazoline
Packaging
250mg
Price
$104
Updated
2021/12/16
Apolloscientific
Product number
OR302328
Product name
2,4-Dichloro-6-methylquinazoline
Purity
97%
Packaging
1g
Price
$234
Updated
2021/12/16
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2,4-DICHLORO-6-METHYLQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

62484-16-6

39576-82-4

6-Methylquinazoline-2,4(1H,3H)-dione (550 mg, 3.12 mmol) was used as a starting material, which was dissolved in POCl3 (4.0 mL), followed by the addition of N,N'-diethylaniline (0.5 mL). The reaction mixture was heated to 135 °C and the reaction was stirred at this temperature for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and carefully poured into ice water. The precipitated solid was collected by filtration and dried to afford 2,4-dichloro-6-methylquinazoline (590 mg, 89% yield), which could be used in subsequent steps without further purification.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 1, p. 461 - 467
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 119 - 132
[3] Patent: WO2004/87680, 2004, A1. Location in patent: Page 162
[4] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 308 - 312
[5] Patent: WO2008/16666, 2008, A2. Location in patent: Page/Page column 49

2,4-DICHLORO-6-METHYLQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLORO-6-METHYLQUINAZOLINE Suppliers

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View Lastest Price from 2,4-DICHLORO-6-METHYLQUINAZOLINE manufacturers

Career Henan Chemical Co
Product
2,4-DICHLORO-6-METHYLQUINAZOLINE 39576-82-4
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

39576-82-4, 2,4-DICHLORO-6-METHYLQUINAZOLINERelated Search:

CHLOROETHANE 4-CHLORO-6-METHYLQUINAZOLINE 2,4-DICHLORO-6-(TRIFLUOROMETHYL)-QUINAZOLINE 2,4-DICHLORO-6-METHYLQUINAZOLINE

  • 2,4-DICHLORO-6-METHYLQUINAZOLINE
  • 6-Methyl-2,4-dichloroquinazoline
  • EOS-60385
  • 2,4-Dichloro-6-methylquinazoline 97%
  • Quinazoline, 2,4-dichloro-6-methyl-
  • 2,4-Dichloro-6-methylquinazoline,97%
  • 39576-82-4