METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE
- Product Name
- METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE
- CAS No.
- 39503-57-6
- Chemical Name
- METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE
- Synonyms
- methyl 5-bromo-4-methylsalicylate;METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE;5-Bromo-2-hydroxy-4-methylbenzoic acid methyl ester;Benzoic acid, 5-bromo-2-hydroxy-4-methyl-, methyl ester
- CBNumber
- CB92455625
- Molecular Formula
- C9H9BrO3
- Formula Weight
- 245.07
- MOL File
- 39503-57-6.mol
METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE Property
- Melting point:
- 48℃
- Density
- 1.548
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M296560
- Product name
- Methyl5-Bromo-2-hydroxy-4-methylbenzoate
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- HCH0037019
- Product name
- METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
- Product number
- 5168AB
- Product name
- Methyl5-bromo-2-hydroxy-4-methylbenzoate
- Packaging
- 5g
- Price
- $293
- Updated
- 2021/12/16
- Product number
- CC00-5414
- Product name
- 5-Bromo-2-hydroxy-4-methyl-benzoicacidmethylester
- Purity
- 97%
- Packaging
- 10g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- CM160194
- Product name
- methyl5-bromo-2-hydroxy-4-methylbenzoate
- Purity
- 95%
- Packaging
- 25g
- Price
- $524
- Updated
- 2021/12/16
METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE Chemical Properties,Usage,Production
Synthesis
67-56-1
6623-35-4
39503-57-6
B) General procedure for synthesizing methyl 5-bromo-2-hydroxy-4-methylbenzoate: sulfuric acid (6.77 mL) was added slowly and dropwise to a solution of methanol (200 mL) containing 5-bromo-2-hydroxy-4-methylbenzoic acid (6.78 g). The reaction mixture was stirred continuously at 70 °C overnight. Upon completion of the reaction, the reaction mixture was concentrated by distillation under reduced pressure. Subsequently, the residue was neutralized with saturated aqueous sodium bicarbonate solution and extracted with ethyl acetate under ice bath cooling conditions. The organic layers were combined, washed sequentially with water and saturated brine, and then dried over anhydrous sodium sulfate. After drying, the solvent was removed by evaporation under reduced pressure. Finally, the residue was purified using silica gel column chromatography (eluent: ethyl acetate/hexane) to afford the target product methyl 5-bromo-2-hydroxy-4-methylbenzoate (6.56 g). The result of mass spectrometry analysis: [M-H]+ 243.0.
References
[1] Patent: WO2018/24224, 2018, A1. Location in patent: Page/Page column 80; 81; 82
[2] Patent: WO2015/163485, 2015, A1. Location in patent: Paragraph 0350
[3] Patent: WO2016/208775, 2016, A1. Location in patent: Paragraph 0394
METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE manufacturers
- Product
- METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE 39503-57-6
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10