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C10-HOMOSERINE LACTONE

Product Name
C10-HOMOSERINE LACTONE
CAS No.
177315-87-6
Chemical Name
C10-HOMOSERINE LACTONE
Synonyms
C10-HSL;C10-HOMOSERINE LACTONE;Decanoyl-L-hoMoserine lactone;N-DECANOYL-L-HOMOSERINE LACTONE;N-[(3S)-2-oxooxolan-3-yl]decanamide;C10-HSL, N-Decanoyl-L-hoMoserine lactone;(S)-N-(2-oxotetrahydrofuran-3-yl)decanamide;N-Decanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide;Decanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
CBNumber
CB92456374
Molecular Formula
C14H25NO3
Formula Weight
255.35
MOL File
177315-87-6.mol
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C10-HOMOSERINE LACTONE Property

Melting point:
127-130 °C
Boiling point:
466.1±34.0 °C(Predicted)
Density 
1.02±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml
form 
A crystalline solid
pka
14.72±0.20(Predicted)
color 
White to off-white
optical activity
[α]/D -24±3°, c = 0.2 in methanol
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
07028
Product name
N-Decanoyl-L-homoserine lactone
Purity
≥96% (HPLC)
Packaging
10mg
Price
$227
Updated
2024/03/01
Sigma-Aldrich
Product number
07028
Product name
N-Decanoyl-L-homoserine lactone
Purity
≥96% (HPLC)
Packaging
50mg
Price
$798
Updated
2023/06/20
Cayman Chemical
Product number
10011201
Product name
N-decanoyl-L-Homoserine lactone
Purity
≥96%
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
10011201
Product name
N-decanoyl-L-Homoserine lactone
Purity
≥96%
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
10011201
Product name
N-decanoyl-L-Homoserine lactone
Purity
≥96%
Packaging
25mg
Price
$193
Updated
2024/03/01
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C10-HOMOSERINE LACTONE Chemical Properties,Usage,Production

Uses

Decanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Burkholderia pseudomallei. Decanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

Definition

ChEBI: N-decanoyl-L-Homoserine lactone is a N-acyl-amino acid.

Biochem/physiol Actions

N-Decanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

C10-HOMOSERINE LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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177315-87-6, C10-HOMOSERINE LACTONERelated Search:

N-OCTANOYL-DL-HOMOSERINE LACTONE N-BUTYRYL-DL-HOMOSERINE LACTONE 3-OXO-DODECANOYL HOMOSERINE LACTONE C7-HSL N-CAPROYL-L-HOMOSERINE LACTONE N-HEPTANOYL-DL-HOMOSERINE LACTONE C8-HSL C10-HOMOSERINE LACTONE

  • N-DECANOYL-L-HOMOSERINE LACTONE
  • C10-HSL, N-Decanoyl-L-hoMoserine lactone
  • Decanoyl-L-hoMoserine lactone
  • C10-HOMOSERINE LACTONE
  • C10-HSL
  • N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide
  • N-[(3S)-2-oxooxolan-3-yl]decanamide
  • Decanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
  • N-Decanoyl-L-homoserine lactone >=96% (HPLC)
  • (S)-N-(2-oxotetrahydrofuran-3-yl)decanamide
  • 177315-87-6