C8-HSL

Product Name: C8-HSL
CAS No.: 147852-84-4
Chemical Name: C8-HSL
Synonyms: OHL;C8-HSL;Octanoyl-L-hoMoserine lactone;N-OCTANOYL-L-HOMOSERINE LACTONE;(3R)-3-(2-Oxononyl)Oxolan-2-One;N-[(3S)-2-oxooxolan-3-yl]octanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide;C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone;N-Octanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide
CBNumber: CB62456373
Molecular Formula: C12H21NO3
Formula Weight: 227.3
MOL File: 147852-84-4.mol

More

Less

C8-HSL Property

Melting point:: 134-135 °C
Boiling point:: 448.1±34.0 °C(Predicted)
Density: 1.04±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 25 mg/ml; DMF:PBS(pH7.2) 1:2: 0.3 mg/ml; DMSO: 20 mg/ml
form: A crystalline solid
pka: 14.83±0.20(Predicted)
color: White to off-white
optical activity: [α]/D -28±3°, c = 0.2 in methanol
BRN: 8148282

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 44558
Product name: N-Octanoyl-L-homoserine lactone
Purity: ≥96% (HPLC)
Packaging: 10mg
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: 44558
Product name: N-Octanoyl-L-homoserine lactone
Purity: ≥96% (HPLC)
Packaging: 50mg
Price: $776
Updated: 2024/03/01

Cayman Chemical

Product number: 10011199
Product name: N-octanoyl-L-Homoserine lactone
Purity: ≥98%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 10011199
Product name: N-octanoyl-L-Homoserine lactone
Purity: ≥98%
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 10011199
Product name: N-octanoyl-L-Homoserine lactone
Purity: ≥98%
Packaging: 25mg
Price: $193
Updated: 2024/03/01

More

Less

C8-HSL Chemical Properties,Usage,Production

Uses

Octanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Yersinia pseudotuberculosis. Octanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

General Description

N-Octanoyl-L-homoserine lactone (C8-HSL) is a N-acyl homoserine lactone (N-acyl-HSL). It is highly nonpolar.

Biochem/physiol Actions

N-Octanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, colonization, chemical defense and cell to cell communication among bacteria; for reviews see. AHLs are released as oligopeptides in Gram positive bacteria and as quorum signal in Gram negative bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

C8-HSL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

C8-HSL Suppliers

Canada 1 China 47 United Kingdom 1 United States 7 Global 56

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Shanghai Leto Pharmatech Co.,Ltd.

Tel: 18016401466
Fax: QQ: 1375988926
Email: sales@letopharm.com
Country: China
ProdList: 213
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9952
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15084
Advantage: 58

147852-84-4, C8-HSLRelated Search:

L-Homoserine Ceftezole Dodecyl acrylate L-Tryptophan L-Methionine 2(3H)-Furanone,3-aminodihydro-(8CI,9CI) 3-OXO-DODECANOYL HOMOSERINE LACTONE N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE C10-HOMOSERINE LACTONE C14:1-DELTA9-CIS-(L)-HSL C8-HSL

N-OCTANOYL-L-HOMOSERINE LACTONE

OHL

C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone

Octanoyl-L-hoMoserine lactone

N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide

N-[(3S)-2-oxooxolan-3-yl]octanamide

C8-HSL

Octanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-

N-Octanoyl-L-homoserine lactone >=96% (HPLC)

(3R)-3-(2-Oxononyl)Oxolan-2-One

(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide

C8-HSL|||N-octanoyl-L-Homoserine lactone|||OHL

147852-84-4