ChemicalBook > CAS DataBase List > C8-HSL

C8-HSL

Product Name: C8-HSL
CAS No.: 147852-84-4
Chemical Name: C8-HSL
Synonyms: OHL;C8-HSL;Octanoyl-L-hoMoserine lactone;N-OCTANOYL-L-HOMOSERINE LACTONE;(3R)-3-(2-Oxononyl)Oxolan-2-One;N-[(3S)-2-oxooxolan-3-yl]octanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide;C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone;N-Octanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide
CBNumber: CB62456373
Molecular Formula: C12H21NO3
Formula Weight: 227.3
MOL File: 147852-84-4.mol

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C8-HSL Property

Melting point:: 134-135 °C
Boiling point:: 448.1±34.0 °C(Predicted)
Density: 1.04±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 25 mg/ml; DMF:PBS(pH7.2) 1:2: 0.3 mg/ml; DMSO: 20 mg/ml
form: A crystalline solid
pka: 14.83±0.20(Predicted)
color: White to off-white
optical activity: [α]/D -28±3°, c = 0.2 in methanol
BRN: 8148282

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 44558
Product name: N-Octanoyl-L-homoserine lactone
Purity: ≥96% (HPLC)
Packaging: 10mg
Price: $177
Updated: 2025/07/31

Sigma-Aldrich

Product number: 44558
Product name: N-Octanoyl-L-homoserine lactone
Purity: ≥96% (HPLC)
Packaging: 50mg
Price: $558.6
Updated: 2025/07/31

TCI Chemical

Product number: O0687
Product name: N-Octanoyl-L-homoserine Lactone
Packaging: 10MG
Price: $144
Updated: 2025/07/31

TCI Chemical

Product number: O0687
Product name: N-Octanoyl-L-homoserine Lactone
Packaging: 50MG
Price: $432
Updated: 2025/07/31

Cayman Chemical

Product number: 10011199
Product name: N-octanoyl-L-Homoserine lactone
Purity: ≥98%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

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C8-HSL Chemical Properties,Usage,Production

Uses

Octanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Yersinia pseudotuberculosis. Octanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

General Description

N-Octanoyl-L-homoserine lactone (C8-HSL) is a N-acyl homoserine lactone (N-acyl-HSL). It is highly nonpolar.

Biochem/physiol Actions

N-Octanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, colonization, chemical defense and cell to cell communication among bacteria; for reviews see. AHLs are released as oligopeptides in Gram positive bacteria and as quorum signal in Gram negative bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

C8-HSL Preparation Products And Raw materials

Raw materials

Preparation Products

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147852-84-4, C8-HSLRelated Search:

L-Homoserine Ceftezole Dodecyl acrylate L-Tryptophan L-Methionine 2(3H)-Furanone,3-aminodihydro-(8CI,9CI) 3-OXO-DODECANOYL HOMOSERINE LACTONE N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE C10-HOMOSERINE LACTONE C14:1-DELTA9-CIS-(L)-HSL C8-HSL

N-OCTANOYL-L-HOMOSERINE LACTONE

OHL

C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone

Octanoyl-L-hoMoserine lactone

N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide

N-[(3S)-2-oxooxolan-3-yl]octanamide

C8-HSL

Octanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-

N-Octanoyl-L-homoserine lactone >=96% (HPLC)

(3R)-3-(2-Oxononyl)Oxolan-2-One

(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide

C8-HSL|||N-octanoyl-L-Homoserine lactone|||OHL

N-Octanoyl-L-homoserine lactone, involved in quorum sensing

N-octanoyl-L-Homoserine lactone, 10 mM in DMSO

<i>N</i>-Octanoyl-<sc>L</sc>-homoserine lactone

2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline disulfonic acid disodium salt (BCP disodium salt)

147852-84-4