2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 142896-15-9
- Chemical Name
- 2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- 6-diMethylpyridine-4-carboxylate;Methyl 2,6-diMethylisonicotinate;2,6- DI METHYL PYRIDINE -4-CARBOXYLATE;Methyl 2,6-diMethylpyridine-4-carboxylate;Methyl 2,6-dimethyl-4-pyridinecarboxylate;2,6-Dimethyl-isonicotinic acid methyl ester;2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER;4-Pyridinecarboxylic acid, 2,6-diMethyl-, Methyl ester;Methyl 2,6-dimethylpyridine-4-carboxylate, 2,6-Dimethyl-4-(methoxycarbonyl)pyridine
- CBNumber
- CB92464803
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 142896-15-9.mol
2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER Property
- Melting point:
- 45 °C
- Boiling point:
- 238.1±35.0 °C(Predicted)
- Density
- 1.078±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 4.55±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M221938
- Product name
- Methyl2,6-Dimethylisonicotinate
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M221938
- Product name
- Methyl2,6-Dimethylisonicotinate
- Packaging
- 50mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 4H23-1-Y2
- Product name
- Methyl 2,6-dimethylisonicotinate
- Packaging
- 250mg
- Price
- $248
- Updated
- 2021/12/16
- Product number
- CHM0398447
- Product name
- 2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.8
- Updated
- 2021/12/16
- Product number
- 189072
- Product name
- Methyl 2,6-dimethylpyridine-4-carboxylate
- Packaging
- 1g
- Price
- $743
- Updated
- 2021/12/16
2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
42521-09-5
544-97-8
142896-15-9
A mixture of methyl 2,6-dichloropyridine-4-carboxylate (2.00 g), dimethylzinc (2N toluene solution, 14.6 mL, 3.0 eq.), and PdCl2(dppf)2 (400 mg, 0.05 eq.) in dioxane (50 mL) was heated for 4 hr. at 80 °C under inert atmosphere. Upon completion of the reaction, the reaction mixture was cooled through an ice bath, quenched with water (100 mL) and filtered through a diatomaceous earth pad. The diatomaceous earth pad was rinsed with water and ethyl acetate (EtOAc). The filtrate was extracted with ethyl acetate (250 mL) and the organic layer was washed with brine (100 mL), dried over anhydrous magnesium sulfate (MgSO4) and concentrated. Purification by fast chromatography (methanol gradient in dichloromethane, 0 to 2%) afforded compound 99 (methyl 2,6-dimethylisonicotinate) as an orange oil in 96% yield.1H-NMR (400 MHz, DMSO): δ 2.51 (s, 6H, 2×CH3), 3.88 (s, 3H, O-CH3), 7.51 (s, 2H, Ar). Mass spectrum (M+H)+ m/z = 166.1.
References
[1] Patent: EP2666775, 2013, A1. Location in patent: Paragraph 0390
[2] Patent: WO2013/174822, 2013, A1. Location in patent: Page/Page column 137
2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER Suppliers
- Tel
- +49 5662 408730
- Fax
- +49 5662 4087320
- info@synchem.de
- Country
- Germany
- ProdList
- 4705
- Advantage
- 70
View Lastest Price from 2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 2,6-DIMETHYLPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER 142896-15-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 100kg
- Release date
- 2020-02-01