1-(2-Chloroethyl)pyrrolidine Hydrochloride
- Product Name
- 1-(2-Chloroethyl)pyrrolidine Hydrochloride
- CAS No.
- 7250-67-1
- Chemical Name
- 1-(2-Chloroethyl)pyrrolidine Hydrochloride
- Synonyms
- 2-Pyrrolidinoethyl;2-chloroethylpyrrolidine;N-Chloroethylpyrprolidine;N-CHLOROETHYL PYRROLIDINE;2-CHLOROETHYLPYRROLIDINE HCL;2-ChloroethylpyrrolidineHcl98%;2-Chloroethylpyrrolidine Hcl 98%;N-(2-Chloroethyl)pyrrolidine HCl;1-(2-CHLOROETHYL)PYRROLIDINE HCL;N-(BETA-CHLOROETHYL)PYRROLIDINE HCL
- CBNumber
- CB9248483
- Molecular Formula
- C6H13Cl2N
- Formula Weight
- 170.08
- MOL File
- 7250-67-1.mol
1-(2-Chloroethyl)pyrrolidine Hydrochloride Property
- Melting point:
- 167-170 °C(lit.)
- Boiling point:
- 237°C(lit.)
- Density
- 0.4[at 20℃]
- vapor pressure
- 1.64hPa at 25℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Water (Slightly)
- form
- Crystalline Powder or Crystals
- color
- White to off-white
- Water Solubility
- Soluble
- Sensitive
- Hygroscopic
- BRN
- 3677061
- InChI
- InChI=1S/C6H12ClN.ClH/c7-3-6-8-4-1-2-5-8;/h1-6H2;1H
- InChIKey
- FSNGFFWICFYWQC-UHFFFAOYSA-N
- SMILES
- N1(CCCl)CCCC1.[H]Cl
- LogP
- 0.736 at 25℃
- CAS DataBase Reference
- 7250-67-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- UY0703150
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C42807
- Product name
- 1-(2-Chloroethyl)pyrrolidine hydrochloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $144
- Updated
- 2024/03/01
- Product number
- C42807
- Product name
- 1-(2-Chloroethyl)pyrrolidine hydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $210.8
- Updated
- 2024/03/01
- Product number
- C1202
- Product name
- 1-(2-Chloroethyl)pyrrolidine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $30
- Updated
- 2024/03/01
- Product number
- B22236
- Product name
- 1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
- Packaging
- 25g
- Price
- $48.65
- Updated
- 2024/03/01
- Product number
- B22236
- Product name
- 1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
- Packaging
- 100g
- Price
- $137.65
- Updated
- 2024/03/01
1-(2-Chloroethyl)pyrrolidine Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystals or crystalline powder
Uses
1-(2-Chloroethyl)pyrrolidine Hydrochloride is a haloalkyl-substituted pyrrolidine used in the preparation of various pharmaceutical compounds, such as the estrogen receptor antagonist Nafoxidine (N212800) and its analogs.
Purification Methods
Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.]
1-(2-Chloroethyl)pyrrolidine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(2-Chloroethyl)pyrrolidine Hydrochloride manufacturers
- Product
- 1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 30 tons
- Release date
- 2024-03-11
- Product
- 1-(2-chloroethyl) pyrrolidine hydrochloride 7250-67-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-09
- Product
- 1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-13