ChemicalBook > CAS DataBase List > 1-(2-Chloroethyl)pyrrolidine Hydrochloride

1-(2-Chloroethyl)pyrrolidine Hydrochloride

Product Name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
CAS No.
7250-67-1
Chemical Name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
Synonyms
2-Pyrrolidinoethyl;2-chloroethylpyrrolidine;N-Chloroethylpyrprolidine;N-CHLOROETHYL PYRROLIDINE;2-CHLOROETHYLPYRROLIDINE HCL;2-ChloroethylpyrrolidineHcl98%;2-Chloroethylpyrrolidine Hcl 98%;N-(2-Chloroethyl)pyrrolidine HCl;1-(2-CHLOROETHYL)PYRROLIDINE HCL;N-(BETA-CHLOROETHYL)PYRROLIDINE HCL
CBNumber
CB9248483
Molecular Formula
C6H13Cl2N
Formula Weight
170.08
MOL File
7250-67-1.mol
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1-(2-Chloroethyl)pyrrolidine Hydrochloride Property

Melting point:
167-170 °C(lit.)
Boiling point:
237°C(lit.)
Density 
0.4[at 20℃]
vapor pressure 
1.64hPa at 25℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Water (Slightly)
form 
Crystalline Powder or Crystals
color 
White to off-white
Water Solubility 
Soluble
Sensitive 
Hygroscopic
BRN 
3677061
InChI
InChI=1S/C6H12ClN.ClH/c7-3-6-8-4-1-2-5-8;/h1-6H2;1H
InChIKey
FSNGFFWICFYWQC-UHFFFAOYSA-N
SMILES
N1(CCCl)CCCC1.[H]Cl
LogP
0.736 at 25℃
CAS DataBase Reference
7250-67-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
UY0703150
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C42807
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity
98%
Packaging
25g
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
C42807
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity
98%
Packaging
100g
Price
$210.8
Updated
2024/03/01
TCI Chemical
Product number
C1202
Product name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
Purity
>98.0%(T)
Packaging
25g
Price
$30
Updated
2024/03/01
Alfa Aesar
Product number
B22236
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging
25g
Price
$48.65
Updated
2024/03/01
Alfa Aesar
Product number
B22236
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging
100g
Price
$137.65
Updated
2024/03/01
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1-(2-Chloroethyl)pyrrolidine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystals or crystalline powder

Uses

1-(2-Chloroethyl)pyrrolidine Hydrochloride is a haloalkyl-substituted pyrrolidine used in the preparation of various pharmaceutical compounds, such as the estrogen receptor antagonist Nafoxidine (N212800) and its analogs.

Purification Methods

Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.]

1-(2-Chloroethyl)pyrrolidine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-Chloroethyl)pyrrolidine Hydrochloride Suppliers

ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD
Tel
18957127338 18957127338
Email
sales@zetchem.com
Country
China
ProdList
439
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
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55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 1-(2-Chloroethyl)pyrrolidine Hydrochloride manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price
US $40.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
30 tons
Release date
2024-03-11
airuikechemical co., ltd.
Product
1-(2-chloroethyl) pyrrolidine hydrochloride 7250-67-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09
Henan Aochuang Chemical Co.,Ltd.
Product
1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13

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