1-(2-Chloroethyl)pyrrolidine Hydrochloride

Product Name: 1-(2-Chloroethyl)pyrrolidine Hydrochloride
CAS No.: 7250-67-1
Chemical Name: 1-(2-Chloroethyl)pyrrolidine Hydrochloride
Synonyms: 2-Pyrrolidinoethyl;2-chloroethylpyrrolidine;N-Chloroethylpyrprolidine;N-CHLOROETHYL PYRROLIDINE;2-CHLOROETHYLPYRROLIDINE HCL;2-ChloroethylpyrrolidineHcl98%;2-Chloroethylpyrrolidine Hcl 98%;N-(2-Chloroethyl)pyrrolidine HCl;1-(2-CHLOROETHYL)PYRROLIDINE HCL;N-(BETA-CHLOROETHYL)PYRROLIDINE HCL
CBNumber: CB9248483
Molecular Formula: C6H13Cl2N
Formula Weight: 170.08
MOL File: 7250-67-1.mol

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1-(2-Chloroethyl)pyrrolidine Hydrochloride Property

Melting point:: 167-170 °C(lit.)
Boiling point:: 237°C(lit.)
Density: 0.4[at 20℃]
vapor pressure: 1.64hPa at 25℃
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Water (Slightly)
form: Crystalline Powder or Crystals
color: White to off-white
Water Solubility: Soluble
Sensitive: Hygroscopic
BRN: 3677061
InChI: InChI=1S/C6H12ClN.ClH/c7-3-6-8-4-1-2-5-8;/h1-6H2;1H
InChIKey: FSNGFFWICFYWQC-UHFFFAOYSA-N
SMILES: N1(CCCl)CCCC1.[H]Cl
LogP: 0.736 at 25℃
CAS DataBase Reference: 7250-67-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/22
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: UY0703150
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C42807
Product name: 1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity: 98%
Packaging: 25g
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: C42807
Product name: 1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity: 98%
Packaging: 100g
Price: $210.8
Updated: 2024/03/01

TCI Chemical

Product number: C1202
Product name: 1-(2-Chloroethyl)pyrrolidine Hydrochloride
Purity: >98.0%(T)
Packaging: 25g
Price: $30
Updated: 2024/03/01

Alfa Aesar

Product number: B22236
Product name: 1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging: 25g
Price: $48.65
Updated: 2024/03/01

Alfa Aesar

Product number: B22236
Product name: 1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging: 100g
Price: $137.65
Updated: 2024/03/01

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1-(2-Chloroethyl)pyrrolidine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystals or crystalline powder

Uses

1-(2-Chloroethyl)pyrrolidine Hydrochloride is a haloalkyl-substituted pyrrolidine used in the preparation of various pharmaceutical compounds, such as the estrogen receptor antagonist Nafoxidine (N212800) and its analogs.

Purification Methods

Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.]

1-(2-Chloroethyl)pyrrolidine Hydrochloride Preparation Products And Raw materials

Raw materials

Acetonitrile Potassium carbonate Chloroform 2-Chloroethanol Hydrochloric acid Dichloromethane Diisopropyl ether Isopropyl alcohol Thionyl chloride Sulfuric acid Pyrrolidine

Preparation Products

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1-(2-Chloroethyl)pyrrolidine Hydrochloride Suppliers

Americas 1 Belgium 4 Canada 4 China 183 Europe 4 Finland 1 France 2 Germany 4 India 29 Japan 1 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 33 Global 287

ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD

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INTATRADE GmbH

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Energy Chemical

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View Lastest Price from 1-(2-Chloroethyl)pyrrolidine Hydrochloride manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price: US $40.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 30 tons
Release date: 2024-03-11

airuikechemical co., ltd.

Product: 1-(2-chloroethyl) pyrrolidine hydrochloride 7250-67-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-09

Henan Aochuang Chemical Co.,Ltd.

Product: 1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-13

7250-67-1, 1-(2-Chloroethyl)pyrrolidine HydrochlorideRelated Search:

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7250-67-1

Building Blocks

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Halogenated Heterocycles

organic synthesis and intermediates

Pharmaceutical raw materials

Pyrrole&Pyrrolidine&Pyrroline