ChemicalBook > CAS DataBase List > DIISOPROPYLCHLOROSILANE

DIISOPROPYLCHLOROSILANE

Product Name
DIISOPROPYLCHLOROSILANE
CAS No.
2227-29-4
Chemical Name
DIISOPROPYLCHLOROSILANE
Synonyms
CHLORODIISOPROPYLSILANE;Diisopropylsilyl chloride;DK677;DK220;DIISOPROPYLCHLOROSILANE;Chlorodiisopropylsilane >chlorobis(propan-2-yl)silane;chloro-di(propan-2-yl)silicon;Silane, chlorobis(1-methylethyl)-;chloro(2,3-dimethylbutan-2-yl)silicon
CBNumber
CB9249415
Molecular Formula
C6H15ClSi
Formula Weight
150.72
MOL File
2227-29-4.mol
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DIISOPROPYLCHLOROSILANE Property

Boiling point:
58-60 °C50 mm Hg(lit.)
Density 
0.883 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.429(lit.)
Flash point:
72 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
generally sol organic solvents; reacts with alcohols, ammonia,and water.
form 
clear liquid
color 
Colorless to Almost colorless
Specific Gravity
0.883
Hydrolytic Sensitivity
8: reacts rapidly with moisture, water, protic solvents
BRN 
2231355
CAS DataBase Reference
2227-29-4(CAS DataBase Reference)
EPA Substance Registry System
Silane, chlorobis(1-methylethyl)- (2227-29-4)
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Safety

Hazard Codes 
C
Risk Statements 
10-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2986 8/PG 2
WGK Germany 
3
F 
10-21
TSCA 
Yes
HazardClass 
3.1
PackingGroup 
II
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
375896
Product name
Chlorodiisopropylsilane
Purity
99%
Packaging
5g
Price
$107
Updated
2023/06/20
Sigma-Aldrich
Product number
375896
Product name
Chlorodiisopropylsilane
Purity
99%
Packaging
25g
Price
$381
Updated
2023/06/20
TCI Chemical
Product number
C1492
Product name
Chlorodiisopropylsilane
Purity
>95.0%(GC)
Packaging
5mL
Price
$106
Updated
2024/03/01
TCI Chemical
Product number
C1492
Product name
Chlorodiisopropylsilane
Purity
>95.0%(GC)
Packaging
25mL
Price
$514
Updated
2024/03/01
Usbiological
Product number
270580
Product name
Chlorodiisopropylsilane
Packaging
2g
Price
$305
Updated
2021/12/16
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DIISOPROPYLCHLOROSILANE Chemical Properties,Usage,Production

Physical properties

bp 150–153°C,bp 54–55°C/45 mmHg; d 0.872 gmL?1

Uses

Intramolecular hydrosilylation is also possible within β-diisopropylsilyloxy esters (13), constituting an exceptionally mild method for reducing ester groups to the aldehyde oxidation level (eq 4).The derivatives (13) may be synthesized from β-hydroxy esters (12) as described above for the analogous ketones. Treatment with fluoride ions (but not Lewis acids) induces hydride transfer to give alkoxysiladioxanes (14) in excellent yields (≥95%). Although usually performed in dichloromethane, the hydrosilylation may also be accomplished with ethyl acetate as solvent, providing strong evidence for intramolecularity.

Preparation

obtained by reaction of trichlorosilane with isopropylmagnesium chloride;the original yield of 45% may be raised to 70–80% by employing conc hydrochloric acid to quench the reaction.

Application

Used in a silylation-reduction-allylation sequence of β-hydroxy esters to homoallylic-substituted 1,3-diols. Used in the silylation-hydrosilation-oxidation of allyl alcohols to 1,3-diols. Reaction carried out in diastereoselective manner. Reduces β-hydroxy ketones to anti-1,3 diols.

Purification Methods

Impurities can be readily detected by 1H NMR. Purify it by fractional distillation [Gilman & Clark J Am Chem Soc 69 1499 1947, Allen et al. J Chem Soc 3668 1957].

DIISOPROPYLCHLOROSILANE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIISOPROPYLCHLOROSILANE Suppliers

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View Lastest Price from DIISOPROPYLCHLOROSILANE manufacturers

Shanghai Daken Advanced Materials Co.,Ltd
Product
DIISOPROPYLCHLOROSILANE 2227-29-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KG /month
Release date
2021-11-26
Career Henan Chemical Co
Product
DIISOPROPYLCHLOROSILANE 2227-29-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-30

2227-29-4, DIISOPROPYLCHLOROSILANERelated Search:

tert-Butylchlorodiphenylsilane Dichloromethane N-OCTYLDIISOPROPYLCHLOROSILANE DI-TERT-BUTYLDICHLOROSILANE 1,3-DICHLORO-1,1,3,3-TETRAISOPROPYLDISILOXANE DIISOPROPYLCHLOROSILANE Triisopropylsilyl chloride 1,1,3,3-TETRACYCLOPENTYLDICHLORODISILOXANE DI-TERT-BUTYLCHLOROSILANE 3-CYANOPROPYLDIISOPROPYLCHLOROSILANE DI-T-BUTYLMETHYLCHLOROSILANE DIISOPROPYLDICHLOROSILANE BIPHENYLDIISOPROPYLSILYL CHLORIDE PHENETHYLDIISOPROPYLCHLOROSILANE Dicyclopentyldichlorosilane DICYCLOHEXYLDICHLOROSILANE PHENYLETHENYLDIISOPROPYLCHLOROSILANE DICYCLOHEXYLMETHYLCHLOROSILANE

  • chloro(2,3-dimethylbutan-2-yl)silicon
  • Silane, chlorobis(1-methylethyl)-
  • CHLORODIISOPROPYLSILANE
  • DIISOPROPYLCHLOROSILANE
  • Diisopropylsilyl chloride
  • chloro-di(propan-2-yl)silicon
  • Chlorodiisopropylsilane &gt
  • chlorobis(propan-2-yl)silane
  • C6H15ClSi DIISOPROPYLCHLOROSILANE 2227-29-4
  • DK220
  • DK677
  • 2227-29-4
  • CH32CH2SiHCl
  • Silicon-Based
  • Synthetic Reagents
  • Protection and Derivatization
  • Protecting and Derivatizing Reagents
  • Monochlorosilanes
  • Reduction
  • Si-H Compounds
  • Si (Classes of Silicon Compounds)
  • Silicon Compounds (for Synthesis)
  • Si-Cl Compounds
  • Pharmaceutical Intermediates
  • Monochlorosilanes
  • Reduction
  • Si (Classes of Silicon Compounds)
  • Si-Cl Compounds
  • Si-H Compounds
  • Silicon Compounds (for Synthesis)
  • Synthetic Organic Chemistry