ChemicalBook > CAS DataBase List > D609

D609

Product Name
D609
CAS No.
83373-60-8
Chemical Name
D609
Synonyms
D609;D609 ,98%;D609,D-609;D-609 POTASSIUM;D609 POTASSIUM SALT;D609 potassium salt,98%;Tricyclodecan-9-yl xanthate;Tricyclodecan-9-yl xanthogenate;tricyclodecane-9-yl-xanthogenate;TRICYCLODECAN-9-YL XANTHOGENATE K
CBNumber
CB9249743
Molecular Formula
C11H17KOS2
Formula Weight
268.47
MOL File
83373-60-8.mol
More
Less

D609 Property

storage temp. 
0-6°C
solubility 
H2O: 300 mg/mL
form 
solid
color 
off-white
Water Solubility 
Soluble to 100 mM in water
More
Less

Safety

Risk Statements 
22
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T8543
Product name
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
Purity
≥95%, solid
Packaging
5mg
Price
$259
Updated
2024/03/01
Sigma-Aldrich
Product number
251400
Product name
D609, Potassium Salt
Packaging
5mg
Price
$289
Updated
2024/03/01
Cayman Chemical
Product number
13307
Product name
D609 (potassium salt)
Purity
≥90%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
13307
Product name
D609 (potassium salt)
Purity
≥90%
Packaging
5mg
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
T8543
Product name
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
Purity
≥95%, solid
Packaging
25mg
Price
$1040
Updated
2024/03/01
More
Less

D609 Chemical Properties,Usage,Production

Description

D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC; Ki = 6.4 μM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations when used at concentrations of 100 and 200 mg/ml, respectively. Similar to other xanthates, D609 has antioxidant, antiviral, and anti-tumor activities. In addition, it has anti-inflammatory actions, inhibiting LPS-stimulated expression of nitric oxide synthase (NOS) in phagocytes (IC50 = 20 μg/ml) and IL-1β-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in endothelial cells.

Chemical Properties

white to off-white solid

Uses

D609 has been used as a phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor in mouse bone marrow derived monocytes. D609 has also been reported to significantly reduce the elevated levels of phosphatidylethanolamine binding protein 1 (PEBP1) in apolipoprotein E-/- mice.

Biological Activity

Selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (K i = 6.4 μ M); antiviral and antitumor agent. Suppresses LPS- and IFN γ -induced NO production (IC 50 = 20 mg/ml) and blocks oxidative glutamate toxicity in nerve cells. Antioxidant in vivo .

Biochem/physiol Actions

D609 can block the production of diacylglycerol (DAG) in the cell. D609 functions by inhibiting the phospholipase C-mediated hydrolysis of the phosphate bond present in phosphatidylcholine and other glycerophospholipids.

storage

Desiccate at -20°C

References

1. a) e. amtmann, drugs exp clin res 1996, 22, 287-294; b) r. m. adibhatla, j. f. hatcher and a. gusain, neurochem res 2012, 37, 671-679. 2. l. paris, s. cecchetti, f. spadaro, l. abalsamo, l. lugini, m. e. pisanu, e. iorio, p. g. natali, c. ramoni and f. podo, breast cancer res 2010, 12, r27. 3. a) k. tschaikowsky, m. meisner, f. schonhuber and e. rugheimer, br j pharmacol 1994, 113, 664-668; b) r. r. cobb, k. a. felts, g. c. parry and n. mackman, mol pharmacol 1996, 49, 998-1004.

D609 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

D609 Suppliers

China 62 Germany 2 India 1 Japan 1 Switzerland 2 United Kingdom 2 United States 20 Global 90
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9635
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9756
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15495
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9635
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19994
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 15093356674;
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30255
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9414
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822 18737195735
Fax
QQ:483339295
Email
483339295@qq.com
Country
China
ProdList
7088
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49391
Advantage
58
Shanghai Binsui Biotechnology Co., Ltd.
Tel
18301908279
Fax
021-54387656
Email
1292752157@qq.com
Country
China
ProdList
10449
Advantage
58
Shanghai Puluokai Medical Technology Co., LTD
Tel
17269768198
Fax
QQ:1213744847
Email
prochemx@163.com
Country
China
ProdList
613
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8141
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
Shanghai guandao biology engineering co., ltd
Tel
18818239863 18818239863
Email
3171921642@qq.com
Country
China
ProdList
8884
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
29778
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
18768175414
Email
gaojun@univ-bio.com
Country
China
ProdList
24998
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18488
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24018
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27996
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7984
Advantage
58
Guangzhou Reullei Pharmaceutical Technology Co., Ltd，
Tel
13660253774
Email
joe@reullei.com
Country
China
ProdList
919
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4164
Advantage
58
Beijing Keyi Tongda Technology Development Co., Ltd
Tel
13681252203
Email
kytd20@sina.com
Country
China
ProdList
1240
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9180
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32686
Advantage
60
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6805
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6164
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6921
Advantage
58
Shanghai Minmin Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1914109725@qq.com
Country
CHINA
ProdList
6530
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6192
Advantage
58
Wuhan Boot Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6829
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6852
Advantage
58
Shanghai Wowu Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shhebio@126.com
Country
CHINA
ProdList
6137
Advantage
58

83373-60-8, D609Related Search:

CYCLOOCTANEMETHANOL ISOPROPYLXANTHIC ACID POTASSIUM SALT N-BUTYLXANTHIC ACID POTASSIUM SALT Potassium Amylxanthate POTASSIUM ISOAMYLXANTHATE Tetrahydrocyclopentadiene D609 potassium O-octyl dithiocarbonate Potassium ethylxanthate TS-609,flocculant TS-609 EINECS 203-609-1 Cyastat 609 caswellno60 Potassium O-Isobutyl Dithiocarbonate 2-CYCLOPENTYL CYCLOPENTANOL Potassium methylxanthate N-PROPYLXANTHIC ACID POTASSIUM SALT BICYCLO[2.2.1]HEPTAN-2-OL

  • TRICYCLODECAN-9-YL XANTHOGENATE K
  • TRICYCLODECAN-9-YL XANTHOGENATE POTASSIUM SALT
  • D609, Potassium Salt - CAS 83373-60-8 - Calbiochem
  • CARBONODITHIOIC ACID, O-(OCTAHYDRO-4,7-METHANO-1H-INDEN-5-YL) ESTER POTASSIUM
  • D609
  • D-609 POTASSIUM
  • D609 POTASSIUM SALT
  • O-TRICYCLO[5.2.1.0(2,6)]DEC-9-YL DITHIOCARBONATE POTASSIUM SALT
  • O-(OCTAHYDRO-4,7-METHANO-1H-INDEN-5-YL) CARBONOPOTASSIUM DITHIOATE
  • potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate
  • O-TRICYCLO(5.2.1.02,6)DEC-9-YL*DITHIOCAR BONATE POTA
  • Dithiocarbonic acid O-[(octahydro-4,7-methano-1H-inden)-5-yl]S-potassium salt
  • Tricyclodecan-9-yl xanthate
  • Tricyclodecan-9-yl xanthate potassium salt
  • Tricyclodecan-9-yl xanthogenate
  • D609 potassium salt,98%
  • Carbonodithioic acid O-(octahydro-4,7-methano-1H-inden-5-yl) ester potassium salt
  • tricyclodecane-9-yl-xanthogenate
  • D609 ,98%
  • CARBONODITHIOIC ACID, O-(OCTAHYDRO-4,7-METH
  • O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate
  • D609,O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonopotassiumdithioate
  • potassium O-(octahydro-1H-4,7-methanoinden-5-yl) carbonodithioate
  • D609,D-609
  • 83373-60-8
  • C11H15KOS2
  • Biochemicals and Reagents
  • BioChemical
  • P to Q
  • Phospholipase C, phosphatidylcholine-specific
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Lipid signaling